Comparing WP_085769774.1 NCBI__GCF_002117405.1:WP_085769774.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 7 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
55% identity, 99% coverage: 1:464/471 of query aligns to 2:464/464 of 4f4fA
1kl7A Crystal structure of threonine synthase from yeast (see paper)
44% identity, 90% coverage: 3:425/471 of query aligns to 7:461/509 of 1kl7A
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
43% identity, 90% coverage: 1:425/471 of query aligns to 5:464/514 of Q42598
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
38% identity, 88% coverage: 3:417/471 of query aligns to 7:433/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
34% identity, 92% coverage: 1:435/471 of query aligns to 1:401/428 of 1vb3A
6nmxA Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
28% identity, 37% coverage: 92:263/471 of query aligns to 41:195/350 of 6nmxA
Sites not aligning to the query:
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
28% identity, 37% coverage: 92:263/471 of query aligns to 39:193/345 of 6cgqB
Sites not aligning to the query:
>WP_085769774.1 NCBI__GCF_002117405.1:WP_085769774.1
MDYISTRGRAPELPFDEVVLTGLAADGGLYVPRRYPTVDHKEIAAFAGRPYAETAETLIA
PFTEGLPRDLLHQAARGAYATFSHAAVAPLTQIGDNLFVLELFHGPTLAFKDLAMQLLGR
LMDALLETRGLRATIVGATSGDTGAAAIEAFRGRANVDVFILYPDGRVSDVQRRQMTTVA
DANVHAIALDGSFDDAQTLLKGLFRDESFRRGVGLAGVNSINWARVVAQMVYYFTSAVTL
GSPHRKISFAVPTGNFGDVLAGYVAKRMGLPVERLIVATNENDILARALATGRYEPRGVT
PTQSPSMDIQLSSNFERLLFDAIGRDSGSVVQAFEALDRDGAFEIPPGALRAVREDFDAL
AVNEAETQAEIARTYRDSGYVIDPHTATGVRAARAQLEKSPGTPVVALSTAHPAKFPDAI
ERAIGLRIEPPPRLAPVLEGKERIARMKRDSETVKRFILEHARAARVGAGA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory