SitesBLAST
Comparing WP_085772004.1 NCBI__GCF_002117405.1:WP_085772004.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8oqrA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-80 (see paper)
41% identity, 98% coverage: 1:714/728 of query aligns to 10:727/728 of 8oqrA
- binding 4-cyanobenzenesulfonic acid: G76 (= G66), G77 (≠ A67), T81 (≠ M71), M82 (≠ L72), M82 (≠ L72), A85 (≠ S75), D89 (≠ E90), T96 (≠ S98), L123 (= L125), G124 (= G126), P149 (= P151), E150 (= E152), S366 (≠ D359), L367 (≠ Q360), E368 (= E361), A420 (= A413), V421 (= V414), F422 (= F415)
8pf8A Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-72 (see paper)
41% identity, 98% coverage: 1:714/728 of query aligns to 10:727/729 of 8pf8A
- binding [2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boronic acid: G76 (= G66), F169 (≠ M171), N173 (≠ D175), S177 (≠ Q178), I193 (≠ A194), F313 (= F306)
- binding bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]-bis(oxidanyl)boranuide: M39 (≠ I30), N40 (≠ T31), E41 (= E32), T81 (≠ M71), D92 (≠ R93), V93 (≠ L94)
- binding [(2~{R})-2,3-bis(oxidanyl)propoxy]-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]borinic acid: M39 (≠ I30), G77 (≠ A67), D78 (= D68), M82 (≠ L72), V93 (≠ L94)
- binding (2~{R})-3-bis[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]boranyloxypropane-1,2-diol: T152 (≠ K154), R184 (≠ Q185), A311 (≠ S304), F312 (≠ L305), I673 (≠ V666)
Sites not aligning to the query:
8oquA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-92 (see paper)
41% identity, 98% coverage: 1:714/728 of query aligns to 11:728/730 of 8oquA
- binding 4-chloranylbenzenesulfonic acid: M40 (≠ I30), N41 (≠ T31), E42 (= E32), G77 (= G66), G78 (≠ A67), D79 (= D68), V80 (≠ L69), D90 (≠ E90), V94 (≠ L94), L124 (= L125), G125 (= G126), P150 (= P151), E151 (= E152)
8oqtA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-91 (see paper)
41% identity, 98% coverage: 1:714/728 of query aligns to 10:727/729 of 8oqtA
- binding 4-bromanylbenzenesulfonic acid: E41 (= E32), G76 (= G66), G77 (≠ A67), D78 (= D68), V79 (≠ L69), M82 (≠ L72), D89 (≠ E90), V93 (≠ L94), T96 (≠ S98), T96 (≠ S98), P149 (= P151), E150 (= E152)
Sites not aligning to the query:
8oqnA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-53 (see paper)
41% identity, 98% coverage: 1:714/728 of query aligns to 10:727/729 of 8oqnA
- binding 1-benzyl-1H-pyrazole-4-carboxylic acid: M39 (≠ I30), M82 (≠ L72), E150 (= E152), Q172 (≠ G174), F175 (vs. gap), V176 (≠ L177), Q181 (≠ K182), T241 (≠ R235), F254 (≠ M246), N257 (= N249), Q261 (≠ R254), L262 (≠ E255), P266 (≠ N259), P268 (= P261), Q282 (= Q275), V283 (≠ L276), G302 (≠ S295), Q303 (≠ K296), V304 (≠ E297), S521 (≠ N514), G525 (≠ L518)
8opvA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with resveratrol (fragment-b-h11) (see paper)
41% identity, 98% coverage: 1:714/728 of query aligns to 10:727/729 of 8opvA
- binding resveratrol: M39 (≠ I30), A75 (≠ G65), G76 (= G66), M82 (≠ L72), E128 (= E130), P149 (= P151), E150 (= E152), T152 (≠ K154), L153 (≠ V155), R184 (≠ Q185), F296 (= F289)
8opuA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with sulfamethoxazole (fragment-b-e1) (see paper)
41% identity, 98% coverage: 1:714/728 of query aligns to 10:727/729 of 8opuA