SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_085772643.1 NCBI__GCF_002117405.1:WP_085772643.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 3 hits to proteins with known functional sites (download)

P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168) (see paper)
31% identity, 26% coverage: 9:82/286 of query aligns to 6:78/358 of P39912

query
sites
P39912
L
 
L
S
 
E
E
 
L
L
 
L
R
 
R
Q
 
Q
E
 
K
I
 
A
D
 
D
R
 
E
I
 
L
D
 
N
L
 
L
S
 
Q
M
 
I
H
 
L
R
 
K
L
 
L
L
 
I
M
 
N
E
 
E
R
 
R
G
 
G
E
 
N
I
 
V
I
 
V
H
 
K
R
 
E
L
 
I
I
 
G
E
 
K
V
 
A
K
 
K
R
 
E
A
 
A
Q
 
Q
G
 
G
A
 
V
G
 
N
C
 
-
A
 
R
F
 
F
R
 
D
P
 
P
D
 
V
R
 
R
E
 
E
A
 
R
Q
 
T
M
 
M
M
 
L
R
 
N
A
 
N
L
 
I
V
 
I
E
 
E
R
 
N
H
 
N
Q
 
D
G
 
G
L
 
P
L
 
F
P
 
E
L
 
N
D
 
S
A
 
T
V
 
I
E
 
Q
G
 
H
I
 
I
W
 
F
R
 
K
V
 
E
I
 
I

Sites not aligning to the query:

5gmuB Crystal structure of chorismate mutase like domain of bifunctional dahp synthase of bacillus subtilis in complex with chlorogenic acid (see paper)
31% identity, 26% coverage: 9:82/286 of query aligns to 5:77/87 of 5gmuB

query
sites
5gmuB
L
 
L
S
 
E
E
 
L
L
 
L
R
 
R
Q
 
Q
E
 
K
I
 
A
D
 
D
R
 
E
I
 
L
D
 
N
L
 
L
S
 
Q
M
 
I
H
 
L
R
 
K
L
 
L
L
 
I
M
 
N
E
 
E
R
|
R
G
 
G
E
 
N
I
 
V
I
 
V
H
 
K
R
 
E
L
 
I
I
 
G
E
 
K
V
 
A
K
 
K
R
 
E
A
 
A
Q
 
Q
G
 
G
A
 
V
G
 
N
C
 
-
A
x
R
F
|
F
R
x
D
P
 
P
D
 
V
R
 
R
E
|
E
A
 
R
Q
 
T
M
 
M
M
 
L
R
 
N
A
 
N
L
 
I
V
 
I
E
 
E
R
 
N
H
 
N
Q
 
D
G
 
G
L
 
P
L
 
F
P
 
E
L
 
N
D
 
S
A
 
T
V
 
I
E
 
Q
G
 
H
I
 
I
W
 
F
R
 
K
V
 
E
I
 
I

Sites not aligning to the query:

5j6fA Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
30% identity, 27% coverage: 7:82/286 of query aligns to 2:76/352 of 5j6fA

query
sites
5j6fA
D
 
E
A
 
R
L
 
L
S
 
D
E
 
E
L
 
L
R
 
R
Q
 
A
E
 
R
I
 
V
D
 
D
R
 
E
I
 
I
D
 
N
L
 
L
S
 
Q
M
 
L
H
 
L
R
 
K
L
 
L
L
 
I
M
 
N
E
 
E
R
|
R
G
 
G
E
 
R
I
 
L
I
 
V
H
 
Q
R
 
E
L
x
I
I
 
G
E
 
K
V
 
I
K
|
K
R
 
E
A
 
A
Q
 
Q
G
 
G
A
 
T
G
 
H
C
 
-
A
 
R
F
x
Y
R
x
D
P
 
P
D
 
V
R
|
R
E
 
E
A
 
R
Q
 
K
M
|
M
M
 
L
R
 
D
A
 
L
L
 
I
V
 
S
E
 
E
R
 
H
H
 
N
Q
 
D
G
 
G
L
 
P
L
 
F
P
 
E
L
 
T
D
 
S
A
 
T
V
 
L
E
 
Q
G
 
H
I
 
I
W
 
F
R
 
K
V
 
E
I
 
I

Sites not aligning to the query:

Query Sequence

>WP_085772643.1 NCBI__GCF_002117405.1:WP_085772643.1
MPPSPADALSELRQEIDRIDLSMHRLLMERGEIIHRLIEVKRAQGAGCAFRPDREAQMMR
ALVERHQGLLPLDAVEGIWRVIVSTFTYVQAPYTVHADDSGGDAQMRDSARFHFGFTVPY
APHHGALAVISAVAASGGDLGVLRASGGSGDGAWWLRLIGDAGPKIIARLPFVERPDHPA
GLPVFVIAKPGAEAASQDIALFSISLPRWTHDAPAAVAAAEGEILAAAPVPGGHSILVAL
PAAQATRLPAALGDANLGAAQIDPVGGHSARFEMDEARAGVFAPEP

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory