Comparing WP_086509351.1 NCBI__GCF_002151265.1:WP_086509351.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7lgpB Dape enzyme from shigella flexneri
62% identity, 96% coverage: 10:382/390 of query aligns to 5:375/377 of 7lgpB
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
64% identity, 93% coverage: 23:383/390 of query aligns to 16:375/377 of 7t1qA
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
59% identity, 95% coverage: 12:383/390 of query aligns to 5:375/376 of 4o23A
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
59% identity, 95% coverage: 12:383/390 of query aligns to 5:375/375 of 4pqaA
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
57% identity, 95% coverage: 13:383/390 of query aligns to 10:379/380 of 5vo3A
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
57% identity, 95% coverage: 13:383/390 of query aligns to 6:375/377 of P44514
4op4B Crystal structure of the catalytic domain of dape protein from v.Cholerea in the zn bound form (see paper)
64% identity, 48% coverage: 10:198/390 of query aligns to 3:188/265 of 4op4B
Sites not aligning to the query:
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
62% identity, 47% coverage: 13:194/390 of query aligns to 8:186/258 of 4h2kA
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
26% identity, 82% coverage: 65:384/390 of query aligns to 95:417/426 of 3pfoA
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
24% identity, 98% coverage: 1:382/390 of query aligns to 1:397/407 of P37111
7uoiA Crystallographic structure of dape from enterococcus faecium
24% identity, 94% coverage: 13:379/390 of query aligns to 11:378/383 of 7uoiA
Q03154 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Homo sapiens (Human) (see 6 papers)
24% identity, 98% coverage: 1:382/390 of query aligns to 1:398/408 of Q03154
7rsfA Acetylornithine deacetylase from escherichia coli
26% identity, 66% coverage: 9:266/390 of query aligns to 2:261/380 of 7rsfA
3rzaA Crystal structure of a tripeptidase (sav1512) from staphylococcus aureus subsp. Aureus mu50 at 2.10 a resolution
26% identity, 94% coverage: 13:378/390 of query aligns to 9:367/373 of 3rzaA
2pokA Crystal structure of a m20 family metallo peptidase from streptococcus pneumoniae
26% identity, 35% coverage: 19:156/390 of query aligns to 30:172/458 of 2pokA
Sites not aligning to the query:
Q96KN2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; EC 3.4.13.20 from Homo sapiens (Human) (see 4 papers)
30% identity, 33% coverage: 69:197/390 of query aligns to 127:254/507 of Q96KN2
Sites not aligning to the query:
3ki9A Crystal structure of staphylococcus aureus metallopeptidase (sapep/dape) in the mn2+ bound form (see paper)
36% identity, 21% coverage: 63:143/390 of query aligns to 74:151/467 of 3ki9A
Sites not aligning to the query:
3dljA Crystal structure of human carnosine dipeptidase 1
30% identity, 33% coverage: 69:197/390 of query aligns to 96:221/471 of 3dljA
Sites not aligning to the query:
Q8C165 N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Peptidase M20 domain-containing protein 1; PM20D1; EC 3.5.1.114; EC 3.5.1.14 from Mus musculus (Mouse) (see paper)
26% identity, 34% coverage: 73:206/390 of query aligns to 124:262/503 of Q8C165
Sites not aligning to the query:
P45494 Beta-Ala-Xaa dipeptidase; Beta-Ala-His dipeptidase; Peptidase V; EC 3.4.13.- from Lactobacillus delbrueckii subsp. lactis (see paper)
34% identity, 23% coverage: 54:143/390 of query aligns to 62:154/470 of P45494
Sites not aligning to the query:
>WP_086509351.1 NCBI__GCF_002151265.1:WP_086509351.1
MPTTEPQGLSPTLQLAMELIRRPSVTPDDLGCQALMIERLERLGFHIERLPFGDVENFWA
THGHHGPVLAFAGHTDVVPSGPHTYWEYPPFEPCIDDDGMLRGRGSADMKGSLAAMITAV
ERFVTAHPDHHGRIAFLITSDEEGPAVDGTRAVVEHLRERHERLDYCIVGEPSSTDVLGD
VIKNGRRGSLGGVLHIKGIQGHVAYPHLARNPIHQAMPALDALVREHWDSGNAFFPATSF
QISNIRAGTGATNVIPGDVEVVFNFRFSTEVTHEQLRERTQAILDAHGLEYQLDWTLNGE
PFLTAEGELVDAALHGVEAVLGRRPKLSTSGGTSDGRFIATLGSQVVELGPRNATIHQTN
ERVRAADLDDLSRIYEAILGKLFVNGSAQP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory