Comparing WP_086509359.1 NCBI__GCF_002151265.1:WP_086509359.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3undB Substrate-bound crystal structure of 2-dehydro-3-deoxyphosphooctonate aldolase from burkholderia pseudomallei (see paper)
69% identity, 95% coverage: 14:285/285 of query aligns to 11:284/284 of 3undB
1g7uA Crystal structures of kdo8p synthase in its binary complex with substrate phosphoenol pyruvate (see paper)
66% identity, 97% coverage: 7:282/285 of query aligns to 3:280/284 of 1g7uA
1g7vA Crystal structures of kdo8p synthase in its binary complexes with the mechanism-based inhibitor (see paper)
66% identity, 97% coverage: 7:282/285 of query aligns to 3:280/284 of 1g7vA
1gg0A Crystal structure analysis of kdop synthase at 3.0 a (see paper)
65% identity, 97% coverage: 7:282/285 of query aligns to 3:271/275 of 1gg0A
1x6uA Kdo8p synthase in it's binary complex with the product kdo8p (see paper)
65% identity, 97% coverage: 7:282/285 of query aligns to 3:268/272 of 1x6uA
1phwA Crystal structure of kdo8p synthase in its binary complex with substrate analog 1-deoxy-a5p (see paper)
65% identity, 97% coverage: 7:282/285 of query aligns to 3:268/272 of 1phwA
1phqA Crystal structure of kdo8p synthase in its binary complex with substrate analog e-fpep
65% identity, 97% coverage: 7:282/285 of query aligns to 3:268/272 of 1phqA
3fyoD Crystal structure of the triple mutant (n23c/d247e/p249a) of 3-deoxy- d-manno-octulosonate 8-phosphate synthase (kdo8ps) from neisseria meningitidis (see paper)
62% identity, 96% coverage: 10:282/285 of query aligns to 3:261/261 of 3fyoD
2nx3D Structural and mechanistic changes along an engineered path from metallo to non-metallo kdo8p synthase (see paper)
53% identity, 85% coverage: 23:263/285 of query aligns to 2:242/262 of 2nx3D
2nx1A Structural and mechanistic changes along an engineered path from metallo to non-metallo kdo8p synthase (see paper)
52% identity, 85% coverage: 23:263/285 of query aligns to 3:243/263 of 2nx1A
3e0iA Cu2+ substituted aquifex aeolicus kdo8ps in complex with pep (see paper)
52% identity, 85% coverage: 23:263/285 of query aligns to 3:243/263 of 3e0iA
2a21A Aquifex aeolicus kdo8ps in complex with pep, po4, and zn2+ (see paper)
52% identity, 85% coverage: 23:263/285 of query aligns to 3:243/263 of 2a21A
1jcyA Aquifex aeolicus kdo8p synthase in complex with r5p, pep and cadmium (see paper)
52% identity, 85% coverage: 23:263/285 of query aligns to 3:243/263 of 1jcyA
1fwwA Aquifex aeolicus kdo8p synthase in complex with pep, a5p and cadmium (see paper)
52% identity, 85% coverage: 23:263/285 of query aligns to 3:243/263 of 1fwwA
1fwtA Aquifex aeolicus kdo8p synthase in complex with pep, e4p and cadmium (see paper)
52% identity, 85% coverage: 23:263/285 of query aligns to 3:243/263 of 1fwtA
3e12A Cu2+ substituted aquifex aeolicus kdo8ps in complex with kdo8p (see paper)
51% identity, 85% coverage: 23:263/285 of query aligns to 3:238/258 of 3e12A
1pe1A Aquifex aeolicus kdo8ps in complex with cadmium and 2-pga (see paper)
51% identity, 85% coverage: 23:263/285 of query aligns to 4:238/258 of 1pe1A
1pcwA Aquifex aeolicus kdo8ps in complex with cadmium and app, a bisubstrate inhibitor (see paper)
51% identity, 85% coverage: 23:263/285 of query aligns to 3:237/257 of 1pcwA
1pckA Aquifex aeolicus kdo8ps in complex with z-methyl-pep (see paper)
51% identity, 85% coverage: 23:263/285 of query aligns to 3:238/258 of 1pckA
1jcxA Aquifex aeolicus kdo8p synthase in complex with api and cadmium (see paper)
50% identity, 85% coverage: 23:263/285 of query aligns to 3:235/255 of 1jcxA
>WP_086509359.1 NCBI__GCF_002151265.1:WP_086509359.1
MTPSTPERHISFAGLTAGNSLPLMLLGGMNVLESRELALEVAETYVEVTGRLGMPYVFKA
SFDKANRSSIHSFRGPGLEKGLEILAEIKQRFGVPVITDVHEPWQAEPVAEVADIIQLPA
FLARQTDLVVAMAKTGAVINIKKPQFLAPHEMRHIIRKCEEAGNDRVLLCERGSSFGYNN
LIVDMLGFGDMKQTGCPVFFDVTHSLQRPGGRADSAGGRRQQVAELARAGIAVGLAGLFL
EAHPDPDSALCDGPCALPLDQLEPFLTQAKALDDLVKGFPALKIE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory