Comparing WP_086510254.1 NCBI__GCF_002151265.1:WP_086510254.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6agmA Molecular basis for feedback inhibition of tyrosine-regulated 3-deoxy- d-arabino-heptulosonate-7-phosphate synthase from escherichia coli (see paper)
58% identity, 98% coverage: 6:355/358 of query aligns to 3:333/334 of 6agmA
1of8A Double complex of the tyrosine sensitive dahp synthase from s. Cerevisiae with co2+, pep and the e4p analogoue g3p (see paper)
52% identity, 95% coverage: 9:348/358 of query aligns to 1:332/339 of 1of8A
1ofoA Crystal structure of the tyrosine regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae in complex with 2-phosphoglycolate (see paper)
52% identity, 95% coverage: 8:348/358 of query aligns to 1:336/344 of 1ofoA
1hfbA Crystal structure of the tyrosine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with phosphoenolpyruvate (see paper)
52% identity, 95% coverage: 9:348/358 of query aligns to 1:331/339 of 1hfbA
1of6A Crystal structure of the tyrosine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with tyrosine and manganese
51% identity, 95% coverage: 8:348/358 of query aligns to 5:343/350 of 1of6A
Sites not aligning to the query:
1ofrC Crystal structure of the tyrosine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with phenylalanine and manganese (see paper)
51% identity, 95% coverage: 8:348/358 of query aligns to 3:340/348 of 1ofrC
Sites not aligning to the query:
4hsoA Crystal structure of s213g variant dah7ps from neisseria meningitidis (see paper)
53% identity, 92% coverage: 17:345/358 of query aligns to 13:335/345 of 4hsoA
5cksB Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase in complex with dahp oxime. (see paper)
53% identity, 93% coverage: 17:348/358 of query aligns to 11:340/345 of 5cksB
8e0sD Dahp (3-deoxy-d-arabinoheptulosonate-7-phosphate) synthase complexed with dahp oxime in unbound:(bound)2:unbound conformations (see paper)
53% identity, 93% coverage: 17:348/358 of query aligns to 10:339/343 of 8e0sD
7rudB Dahp synthase complex with trifluoropyruvate oxime (see paper)
53% identity, 93% coverage: 17:348/358 of query aligns to 10:339/343 of 7rudB
1kflA Crystal structure of phenylalanine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase (dahp synthase) from e.Coli complexed with mn2+, pep, and phe (see paper)
52% identity, 97% coverage: 3:348/358 of query aligns to 2:345/350 of 1kflA
P0AB91 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase; EC 2.5.1.54 from Escherichia coli (strain K12) (see paper)
52% identity, 97% coverage: 3:348/358 of query aligns to 2:345/350 of P0AB91
7reuB Crystal structure of aro4p, 3-deoxy-d-arabino-heptulosonate-7- phosphate (dahp) synthase from candida auris, l-tyr complex
48% identity, 99% coverage: 4:357/358 of query aligns to 1:355/358 of 7reuB
1qr7A Crystal structure of phenylalanine-regulated 3-deoxy-d-arabino- heptulosonate-7-phosphate synthase from escherichia coli complexed with pb2+ and pep (see paper)
54% identity, 92% coverage: 17:346/358 of query aligns to 9:331/338 of 1qr7A
4umcA Structural analysis of substrate-mimicking inhibitors in complex with neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water (see paper)
53% identity, 92% coverage: 17:345/358 of query aligns to 3:325/334 of 4umcA
5dceA Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase regulated (tryptophan) (see paper)
53% identity, 92% coverage: 17:345/358 of query aligns to 13:335/344 of 5dceA
5dcbC Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase regulated and complexed with pep
53% identity, 92% coverage: 17:345/358 of query aligns to 17:339/348 of 5dcbC
4umbA Structural analysis of substrate-mimicking inhibitors in complex with neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water (see paper)
53% identity, 92% coverage: 17:345/358 of query aligns to 3:325/335 of 4umbA
5dcdA Neisseria meningitidis 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase regulated (tyrosine)
53% identity, 92% coverage: 17:345/358 of query aligns to 15:337/346 of 5dcdA
1gg1A Crystal structure analysis of dahp synthase in complex with mn2+ and 2-phosphoglycolate (see paper)
53% identity, 92% coverage: 17:346/358 of query aligns to 10:333/339 of 1gg1A
>WP_086510254.1 NCBI__GCF_002151265.1:WP_086510254.1
MSDQQVSNLNVLSQDVLITPEALKNEIPLGDVAERTVIEGRRTIQNILDGSDPRLLVVVG
PCSIHDVDAALDYARRLRRLADEVKDSLFIVMRVYFEKPRTTVGWKGLINDPHLNGSFEI
EEGLHIARKLLVELSELGLPLATEALDPISPQYLQDCISWSAIGARTTESQTHREMSSGL
SSPVGFKNGTDGSLDVAINALQSVSHPHNFLGINQSGQVAIIRTRGNAYAHVVLRGGNGK
PNYDSVSVALAEQELKKAGIKPNIMIDCSHANSNKDPALQPLVLDNVTNQILEGNRSIMG
LMVESNIGWGSQKILDDHSQMQYGVSVTDACIDWATTEETMTRMASKLSPVLTERRQG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory