Comparing WP_086511126.1 NCBI__GCF_002151265.1:WP_086511126.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
7rk5B Mannitol-2-dehydrogenase bound to nadh from aspergillus fumigatus
49% identity, 97% coverage: 16:490/491 of query aligns to 21:499/501 of 7rk5B
1m2wA Pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with NAD and d-mannitol (see paper)
47% identity, 99% coverage: 4:489/491 of query aligns to 3:489/492 of 1m2wA
1lj8A Crystal structure of mannitol dehydrogenase in complex with NAD (see paper)
47% identity, 99% coverage: 4:489/491 of query aligns to 3:489/492 of 1lj8A
4im7A Crystal structure of fructuronate reductase (ydfi) from e. Coli cft073 (efi target efi-506389) complexed with nadh and d-mannonate
41% identity, 97% coverage: 12:485/491 of query aligns to 3:477/483 of 4im7A
P09424 Mannitol-1-phosphate 5-dehydrogenase; EC 1.1.1.17 from Escherichia coli (strain K12) (see paper)
24% identity, 42% coverage: 170:375/491 of query aligns to 99:293/382 of P09424
>WP_086511126.1 NCBI__GCF_002151265.1:WP_086511126.1
MPALSNATLSHLDSRVAVPRYDRREVTPGIVHIGVGGFHRAHQAMYLDALMNRGEALDWG
IVGVGVMPGDRRMQEVLAAQDHLYTLVVKHPNGEREPRVIGAMLDYLYAPDDPEAVVERM
ADPAIRIVSLTVTEGGYNFHPVTGEFDLANPDVRHDLDSPAAPRTTFGLVVEALARRRAR
GLAPFTLMSCDNIQGNGEVARRMFVAFARARDPALAEWIEAEVPFPNAMVDRITPVTQAV
DIEELAGEFGVEDAWPVVCEPFTQWVLEDHFICGRPAFERVGVQVVEDVEPYELMKLRLL
NASHQALCYFGTLAGYRYAHEVCRDPLFVDFLLGYMRHEGSPTLAPVPGVDLEQYRLTLI
ERFANPEIKDTLARLCAESSDRIPKWLVPVIREQLAKGGEIHRSAAVVASWARYAEGLDE
QGEPITVVDRLKHELAALAAENRTRPGAFIENRELFGDLAEHERFRQAYLMALTSLHERG
ARATLETLVGE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory