SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_089219592.1 NCBI__GCF_900188165.1:WP_089219592.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

1qwrA Crystal structure analysis of the mannose 6-phosphate isomerase from bacillus subtilis
39% identity, 51% coverage: 49:189/277 of query aligns to 81:226/315 of 1qwrA

query
sites
1qwrA
L
 
L
L
 
L
V
 
T
K
 
K
Y
 
L
L
 
L
F
 
D
T
 
V
S
 
K
E
 
E
K
 
D
L
 
T
S
 
S
I
 
I
Q
 
K
V
 
V
H
|
H
P
 
P
D
 
D
D
 
D
K
 
Y
-
 
Y
A
 
A
A
 
G
Q
 
E
A
 
N
R
 
E
G
 
E
L
 
G
P
 
E
R
 
L
G
 
G
K
 
K
D
 
T
E
|
E
A
 
C
W
 
W
V
 
Y
V
 
I
L
 
I
A
 
D
A
 
C
D
 
K
Q
 
E
R
 
N
A
 
A
S
 
E
I
 
I
G
 
I
V
 
Y
G
 
G
M
 
-
R
 
H
H
 
T
V
 
A
M
 
R
T
 
S
Q
 
K
D
 
T
E
 
E
L
 
L
R
 
V
A
 
T
A
 
M
A
 
I
I
 
N
D
 
S
G
 
G
S
 
D
I
 
W
E
 
E
D
 
G
K
 
L
L
 
L
F
 
R
W
 
R
K
 
I
P
 
K
V
 
I
K
 
K
S
 
P
G
 
G
D
 
D
V
 
F
F
 
Y
Y
 
Y
S
 
V
P
 
P
A
 
S
G
 
G
T
 
T
V
 
L
H
|
H
A
 
A
I
 
L
G
 
C
A
 
K
G
 
G
L
 
A
T
 
L
L
 
V
V
 
L
E
 
E
V
 
T
Q
 
Q
Q
 
Q
N
 
N
V
 
S
D
 
D
C
 
A
T
 
T
Y
 
Y
R
 
R
L
 
V
Y
 
Y
D
 
D
Y
 
Y
-
 
D
-
 
R
-
 
L
-
 
D
-
 
S
-
 
N
G
 
G
R
 
S
P
 
P
R
 
R
E
 
E
L
 
L
H
 
H
L
 
F
D
 
A
D
 
K
G
 
A
V
 
V
A
 
N
A
 
A
S
 
A
R
 
-
P
 
T
V
 
V
P
 
P
Y
 
H
V
 
V
T
 
D
P
 
G
H
 
Y
V
 
I

P39841 Putative mannose-6-phosphate isomerase YvyI; Phosphohexomutase; Phosphomannose isomerase; PMI; EC 5.3.1.8 from Bacillus subtilis (strain 168)
39% identity, 51% coverage: 49:189/277 of query aligns to 82:227/316 of P39841

query
sites
P39841
L
 
L
L
 
L
V
 
T
K
 
K
Y
 
L
L
 
L
F
 
D
T
 
V
S
 
K
E
 
E
K
 
D
L
 
T
S
 
S
I
 
I
Q
 
K
V
 
V
H
|
H
P
 
P
D
 
D
D
 
D
K
 
Y
-
 
Y
A
 
A
A
 
G
Q
 
E
A
 
N
R
 
E
G
 
E
L
 
G
P
 
E
R
 
L
G
 
G
K
 
K
D
 
T
E
|
E
A
 
C
W
 
W
V
 
Y
V
 
I
L
 
I
A
 
D
A
 
C
D
 
K
Q
 
E
R
 
N
A
 
A
S
 
E
I
 
I
G
 
I
V
 
Y
G
 
G
M
 
-
R
 
H
H
 
T
V
 
A
M
 
R
T
 
S
Q
 
K
D
 
T
E
 
E
L
 
L
R
 
V
A
 
T
A
 
M
A
 
I
I
 
N
D
 
S
G
 
G
S
 
D
I
 
W
E
 
E
D
 
G
K
 
L
L
 
L
F
 
R
W
 
R
K
 
I
P
 
K
V
 
I
K
 
K
S
 
P
G
 
G
D
 
D
V
 
F
F
 
Y
Y
 
Y
S
 
V
P
 
P
A
 
S
G
 
G
T
 
T
V
 
L
H
|
H
A
 
A
I
 
L
G
 
C
A
 
K
G
 
G
L
 
A
T
 
L
L
 
V
V
 
L
E
 
E
V
 
T
Q
 
Q
Q
 
Q
N
 
N
V
 
S
D
 
D
C
 
A
T
 
T
Y
 
Y
R
 
R
L
 
V
Y
 
Y
D
 
D
Y
 
Y
-
 
D
-
 
R
-
 
L
-
 
D
-
 
S
-
 
N
G
 
G
R
 
S
P
 
P
R
 
R
E
 
E
L
 
L
H
 
H
L
 
F
D
 
A
D
 
K
G
 
A
V
 
V
A
 
N
A
 
A
S
 
A
R
 
-
P
 
T
V
 
V
P
 
P
Y
 
H
V
 
V
T
 
D
P
 
G
H
 
Y
V
 
I

Query Sequence

>WP_089219592.1 NCBI__GCF_900188165.1:WP_089219592.1
MPAIRLTTKRVEKPWGRRQLGAGFDDVAAGGAPVGEIWFELPGGGDPELLVKYLFTSEKL
SIQVHPDDKAAQARGLPRGKDEAWVVLAADQRASIGVGMRHVMTQDELRAAAIDGSIEDK
LFWKPVKSGDVFYSPAGTVHAIGAGLTLVEVQQNVDCTYRLYDYGRPRELHLDDGVAASR
PVPYVTPHVPRELGGGRTALAYGPALVLERWAGARRTAVKAGEGRPIWLIPIGGNGTIDG
EPFAPGGVWLVEDDATIDVNEQSFILVAYPGADIIGG

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory