SitesBLAST
Comparing WP_090216616.1 NCBI__GCF_002796795.1:WP_090216616.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
6x9aA Structure of proline utilization a with trans-4-hydroxy-d-proline bound in the l-glutamate-gamma-semialdehyde dehydrogenase active site (see paper)
48% identity, 97% coverage: 26:1131/1135 of query aligns to 37:1211/1214 of 6x9aA
- active site: N688 (= N659), K711 (= K682), E791 (= E760), C825 (= C794), E921 (= E887), A1003 (= A969)
- binding flavin-adenine dinucleotide: D287 (= D280), A288 (= A281), V319 (= V312), R348 (= R341), V350 (= V343), K351 (= K344), G352 (= G345), A353 (= A346), Y354 (= Y347), W355 (= W348), F373 (≠ Y366), T374 (= T367), R375 (≠ N368), K376 (= K369), T379 (= T372), A402 (= A395), T403 (= T396), H404 (= H397), N405 (= N398), C429 (≠ R419), E473 (= E461), S479 (= S467), F480 (= F468)
- binding (4S)-4-hydroxy-D-proline: W555 (= W537), T556 (≠ V538), E655 (= E631), F689 (= F660), R725 (≠ Q696), S826 (= S795), G983 (= G949), A984 (= A950), F991 (= F957)
6x9dA Structure of proline utilization a with trans-4-hydroxy-l-proline bound in the l-glutamate-gamma-semialdehyde dehydrogenase active site (see paper)
49% identity, 97% coverage: 26:1131/1135 of query aligns to 37:1215/1218 of 6x9dA
- active site: N692 (= N659), K715 (= K682), E795 (= E760), C829 (= C794), E925 (= E887), A1007 (= A969)
- binding flavin-adenine dinucleotide: D291 (= D280), A292 (= A281), V323 (= V312), Q325 (= Q314), R352 (= R341), V354 (= V343), K355 (= K344), G356 (= G345), A357 (= A346), Y358 (= Y347), W359 (= W348), F377 (≠ Y366), T378 (= T367), R379 (≠ N368), K380 (= K369), T383 (= T372), A406 (= A395), T407 (= T396), H408 (= H397), N409 (= N398), Q432 (= Q418), C433 (≠ R419), E477 (= E461), S483 (= S467), F484 (= F468)
- binding 4-hydroxyproline: E659 (= E631), F693 (= F660), I697 (= I664), R828 (= R793), S830 (= S795), G987 (= G949), A988 (= A950), F995 (= F957)
- binding nicotinamide-adenine-dinucleotide: I688 (= I655), S689 (= S656), P690 (= P657), W691 (= W658), N692 (= N659), I697 (= I664), K715 (= K682), A717 (= A684), E718 (= E685), G748 (= G715), G751 (= G719), A752 (≠ P720), T766 (= T734), G767 (= G735), S768 (= S736), V771 (≠ T739), E795 (= E760), T796 (= T761), C829 (= C794), E925 (= E887), F927 (= F889), F995 (= F957)
7mybA Structure of proline utilization a with tetrahydrothiophene-2- carboxylate bound in the proline dehydrogenase active site (see paper)
48% identity, 97% coverage: 26:1131/1135 of query aligns to 37:1214/1217 of 7mybA
- binding flavin-adenine dinucleotide: D290 (= D280), A291 (= A281), V322 (= V312), Q324 (= Q314), R351 (= R341), V353 (= V343), K354 (= K344), G355 (= G345), A356 (= A346), Y357 (= Y347), W358 (= W348), F376 (≠ Y366), T377 (= T367), R378 (≠ N368), K379 (= K369), T382 (= T372), A405 (= A395), T406 (= T396), H407 (= H397), N408 (= N398), C432 (≠ R419), L433 (= L420), E476 (= E461), S482 (= S467), F483 (= F468)
- binding nicotinamide-adenine-dinucleotide: I687 (= I655), S688 (= S656), P689 (= P657), W690 (= W658), N691 (= N659), I696 (= I664), K714 (= K682), E717 (= E685), G747 (= G715), G750 (= G719), T765 (= T734), G766 (= G735), S767 (= S736), V770 (≠ T739), I774 (= I743), E794 (= E760), T795 (= T761), C828 (= C794), E924 (= E887), F926 (= F889), F994 (= F957)
- binding (2S)-thiolane-2-carboxylic acid: K249 (= K239), Y457 (= Y442), Y469 (= Y454), R472 (= R457), R473 (= R458)
- binding (2R)-thiolane-2-carboxylic acid: K249 (= K239), D290 (= D280), Y457 (= Y442), Y469 (= Y454), R472 (= R457), R473 (= R458)
7myaA Structure of proline utilization a with the fad covalently-modified by 1,3-dithiolane (see paper)
48% identity, 97% coverage: 26:1131/1135 of query aligns to 37:1214/1217 of 7myaA