SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_090448709.1 NCBI__GCF_900100495.1:WP_090448709.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
30% identity, 94% coverage: 5:219/229 of query aligns to 11:213/215 of 4ymtC

query
sites
4ymtC
Y
 
Y
G
 
T
S
 
P
T
 
L
I
 
F
L
 
I
E
 
S
G
 
G
A
 
L
W
 
I
L
 
M
T
 
T
L
 
L
M
 
K
L
 
L
A
 
T
L
 
F
S
 
L
S
 
A
V
 
V
A
 
T
V
 
I
A
 
G
I
 
V
L
 
L
L
 
M
G
 
G
L
 
L
L
 
F
G
 
I
A
 
A
A
 
L
F
 
M
R
 
K
L
 
M
S
 
S
P
 
S
V
 
I
K
 
K
W
 
P
L
 
I
A
 
K
A
 
L
L
 
V
G
 
A
E
 
S
T
 
S
Y
 
Y
A
 
I
T
 
E
V
 
V
I
 
I
R
 
R
G
 
G
I
 
T
P
|
P
D
x
L
L
 
L
V
 
V
L
 
Q
I
 
L
L
 
L
L
 
L
I
 
I
F
 
Y
Y
 
N
G
 
G
G
 
-
Q
 
-
D
 
-
M
 
-
V
 
-
N
 
-
R
 
-
V
 
-
A
 
-
P
 
-
M
 
L
L
 
M
G
 
Q
Y
 
F
D
 
G
E
 
-
Y
 
-
I
 
M
D
 
N
I
 
I
N
 
P
P
 
A
F
 
F
I
 
T
A
 
A
G
 
G
V
 
V
F
 
S
T
 
A
M
 
L
G
 
A
F
 
I
I
x
N
F
 
S
G
 
S
A
 
A
Y
|
Y
L
 
V
S
 
A
E
 
E
T
 
I
F
 
I
R
 
R
G
 
A
A
 
G
F
 
I
M
 
Q
A
 
A
I
 
V
P
 
D
K
 
P
G
 
G
Q
 
Q
A
 
N
E
 
E
A
 
A
G
 
A
L
 
R
A
 
S
Y
 
L
G
 
G
M
 
M
S
 
T
G
 
H
A
 
A
K
 
M
V
 
A
F
 
M
F
 
R
R
 
Y
I
 
V
L
 
I
V
 
I
P
 
P
Q
 
Q
M
 
A
I
 
I
R
 
K
F
 
N
A
 
I
I
 
L
P
 
P
G
 
A
F
 
L
T
 
G
N
 
N
N
x
E
W
 
F
L
 
I
V
 
V
L
x
M
T
 
L
K
|
K
A
x
E
T
 
S
A
 
A
L
 
I
I
 
V
S
 
S
V
 
V
V
 
I
G
 
G
L
 
F
Q
 
A
D
 
D
M
 
L
M
 
T
F
 
R
K
 
Q
A
 
A
K
 
D
S
 
I
A
 
I
A
 
Q
D
 
S
A
 
V
T
 
T
R
 
Y
E
 
R
P
 
Y
F
 
F
T
 
E
F
 
P
Y
 
Y
L
 
I
A
 
I
V
 
I
A
 
A
A
 
A
L
 
I
Y
 
Y
L
 
F
V
 
V
L
 
M
T
 
T
S
 
L
V
 
T
S
 
F
L
 
S
L
 
K
A
 
L
L
 
L
R
 
S
F
 
L
L
 
F
D
 
E
K
 
R
R
 
R

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
30% identity, 94% coverage: 5:219/229 of query aligns to 11:213/214 of 4ymwC

query
sites
4ymwC
Y
 
Y
G
 
T
S
 
P
T
 
L
I
 
F
L
 
I
E
 
S
G
 
G
A
 
L
W
 
I
L
 
M
T
 
T
L
 
L
M
 
K
L
 
L
A
 
T
L
 
F
S
 
L
S
 
A
V
 
V
A
 
T
V
 
I
A
 
G
I
 
V
L
 
L
L
 
M
G
 
G
L
 
L
L
 
F
G
 
I
A
 
A
A
 
L
F
 
M
R
 
K
L
 
M
S
 
S
P
 
S
V
 
I
K
 
K
W
 
P
L
 
I
A
 
K
A
 
L
L
 
V
G
 
A
E
 
S
T
 
S
Y
 
Y
A
 
I
T
 
E
V
 
V
I
 
I
R
 
R
G
 
G
I
 
T
P
 
P
D
 
L
L
 
L
V
 
V
L
 
Q
I
 
L
L
 
L
L
 
L
I
 
I
F
 
Y
Y
 
N
G
 
G
G
 
-
Q
 
-
D
 
-
M
 
-
V
 
-
N
 
-
R
 
-
V
 
-
A
 
-
P
 
-
M
 
L
L
 
M
G
 
Q
Y
 
F
D
 
G
E
 
-
Y
 
-
I
 
M
D
 
N
I
 
I
N
 
P
P
 
A
F
 
F
I
 
T
A
 
A
G
 
G
V
 
V
F
 
S
T
 
A
M
 
L
G
 
A
F
 
I
I
x
N
F
 
S
G
 
S
A
 
A
Y
|
Y
L
 
V
S
 
A
E
 
E
T
 
I
F
 
I
R
 
R
G
 
A
A
 
G
F
 
I
M
 
Q
A
 
A
I
 
V
P
 
D
K
 
P
G
 
G
Q
 
Q
A
 
N
E
 
E
A
 
A
G
 
A
L
 
R
A
 
S
Y
 
L
G
 
G
M
 
M
S
 
T
G
 
H
A
 
A
K
 
M
V
 
A
F
 
M
F
 
R
R
 
Y
I
 
V
L
 
I
V
 
I
P
 
P
Q
 
Q
M
 
A
I
 
I
R
 
K
F
 
N
A
 
I
I
 
L
P
 
P
G
 
A
F
 
L
T
 
G
N
 
N
N
x
E
W
 
F
L
 
I
V
 
V
L
 
M
T
 
L
K
 
K
A
x
E
T
 
S
A
 
A
L
 
I
I
 
V
S
 
S
V
 
V
V
 
I
G
 
G
L
 
F
Q
 
A
D
 
D
M
 
L
M
 
T
F
 
R
K
 
Q
A
 
A
K
 
D
S
 
I
A
 
I
A
 
Q
D
 
S
A
 
V
T
 
T
R
 
Y
E
 
R
P
 
Y
F
 
F
T
 
E
F
 
P
Y
 
Y
L
 
I
A
 
I
V
 
I
A
 
A
A
 
A
L
 
I
Y
 
Y
L
 
F
V
 
V
L
 
M
T
 
T
S
 
L
V
 
T
S
 
F
L
 
S
L
 
K
A
 
L
L
 
L
R
 
S
F
 
L
L
 
F
D
 
E
K
 
R
R
 
R

Query Sequence

>WP_090448709.1 NCBI__GCF_900100495.1:WP_090448709.1
MLNGYGSTILEGAWLTLMLALSSVAVAILLGLLGAAFRLSPVKWLAALGETYATVIRGIP
DLVLILLIFYGGQDMVNRVAPMLGYDEYIDINPFIAGVFTMGFIFGAYLSETFRGAFMAI
PKGQAEAGLAYGMSGAKVFFRILVPQMIRFAIPGFTNNWLVLTKATALISVVGLQDMMFK
AKSAADATREPFTFYLAVAALYLVLTSVSLLALRFLDKRYSVGTKAADL

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory