SitesBLAST
Comparing WP_094578795.1 NCBI__GCF_002252475.1:WP_094578795.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3meqA Crystal structure of alcohol dehydrogenase from brucella melitensis
92% identity, 99% coverage: 3:343/344 of query aligns to 1:341/341 of 3meqA
- active site: C40 (= C42), H41 (= H43), T42 (= T44), H45 (= H47), H63 (= H65), E64 (= E66), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), L112 (= L114), C150 (= C152), T154 (= T156), R335 (= R337)
- binding 1,4-dihydronicotinamide adenine dinucleotide: C40 (= C42), H41 (= H43), T42 (= T44), H45 (= H47), C150 (= C152), T154 (= T156), G176 (= G178), G177 (= G179), L178 (= L180), D197 (= D199), I198 (= I200), K202 (= K204), T241 (= T243), A242 (= A244), V243 (= V245), S244 (= S246), A247 (= A249), N264 (= N266), G265 (= G267), L266 (= L268), I289 (= I291), V290 (= V292)
- binding zinc ion: C40 (= C42), H63 (= H65), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), C150 (= C152)
3s2fE Crystal structure of furx nadh:furfural
75% identity, 99% coverage: 5:344/344 of query aligns to 3:340/340 of 3s2fE
- active site: C40 (= C42), H41 (= H43), T42 (= T44), H45 (= H47), H63 (= H65), E64 (= E66), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), Q112 (≠ L114), C150 (= C152), T154 (= T156), R333 (= R337)
- binding furfural: T42 (= T44), W51 (= W53), H63 (= H65), W89 (= W91), C150 (= C152), I287 (= I291)
- binding nicotinamide-adenine-dinucleotide: C40 (= C42), H41 (= H43), T42 (= T44), C150 (= C152), T154 (= T156), G174 (= G176), G176 (= G178), G177 (= G179), L178 (= L180), D197 (= D199), I198 (= I200), K202 (= K204), T239 (= T243), A240 (= A244), V241 (= V245), N262 (= N266), G263 (= G267), L264 (= L268), I287 (= I291), V288 (= V292), R333 (= R337)
- binding zinc ion: C40 (= C42), H63 (= H65), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), C150 (= C152)
3s2fA Crystal structure of furx nadh:furfural
75% identity, 99% coverage: 5:344/344 of query aligns to 3:340/340 of 3s2fA
- active site: C40 (= C42), H41 (= H43), T42 (= T44), H45 (= H47), H63 (= H65), E64 (= E66), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), Q112 (≠ L114), C150 (= C152), T154 (= T156), R333 (= R337)
- binding phosphorylisopropane: T42 (= T44), H63 (= H65), W89 (= W91), I287 (= I291)
- binding zinc ion: C40 (= C42), H63 (= H65), E64 (= E66), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), C150 (= C152)
3s2eE Crystal structure of furx nadh complex 1
75% identity, 99% coverage: 5:344/344 of query aligns to 3:340/340 of 3s2eE
- active site: C40 (= C42), H41 (= H43), T42 (= T44), H45 (= H47), H63 (= H65), E64 (= E66), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), Q112 (≠ L114), C150 (= C152), T154 (= T156), R333 (= R337)
- binding nicotinamide-adenine-dinucleotide: C40 (= C42), H41 (= H43), T42 (= T44), C150 (= C152), T154 (= T156), G176 (= G178), G177 (= G179), L178 (= L180), D197 (= D199), I198 (= I200), K202 (= K204), T239 (= T243), A240 (= A244), V241 (= V245), S242 (= S246), A245 (= A249), N262 (= N266), G263 (= G267), L264 (= L268), I287 (= I291), V288 (= V292)
- binding zinc ion: C40 (= C42), H63 (= H65), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), C150 (= C152)
3s2eA Crystal structure of furx nadh complex 1
75% identity, 99% coverage: 5:344/344 of query aligns to 3:340/340 of 3s2eA
- active site: C40 (= C42), H41 (= H43), T42 (= T44), H45 (= H47), H63 (= H65), E64 (= E66), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), Q112 (≠ L114), C150 (= C152), T154 (= T156), R333 (= R337)
- binding zinc ion: C40 (= C42), H63 (= H65), E64 (= E66), C94 (= C96), C97 (= C99), C100 (= C102), C108 (= C110), C150 (= C152)
6z42A The low resolution structure of a zinc-dependent alcohol dehydrogenase from halomonas elongata.
74% identity, 99% coverage: 3:342/344 of query aligns to 2:335/336 of 6z42A
- active site: C41 (= C42), T43 (= T44), H46 (= H47), H64 (= H65), C148 (= C152)
- binding zinc ion: C41 (= C42), H64 (= H65), E65 (= E66), C95 (= C96), C98 (= C99), C101 (= C102), C109 (= C110), C148 (= C152)
Q8GIX7 Alcohol dehydrogenase; ADH; EC 1.1.1.1 from Moraxella sp. (strain TAE123) (see paper)
73% identity, 99% coverage: 5:343/344 of query aligns to 1:337/338 of Q8GIX7
- C38 (= C42) binding Zn(2+)
- H61 (= H65) binding Zn(2+)
- E62 (= E66) binding Zn(2+)
- C92 (= C96) binding Zn(2+)
- C95 (= C99) binding Zn(2+)
- C98 (= C102) binding Zn(2+)
- C106 (= C110) binding Zn(2+)
- C148 (= C152) binding Zn(2+)
4z6kA Alcohol dehydrogenase from the antarctic psychrophile moraxella sp. Tae 123
73% identity, 99% coverage: 5:343/344 of query aligns to 1:337/345 of 4z6kA
- active site: C38 (= C42), H39 (= H43), T40 (= T44), H43 (= H47), H61 (= H65), E62 (= E66), C92 (= C96), C95 (= C99), C98 (= C102), C106 (= C110), Q110 (≠ L114), C148 (= C152), T152 (= T156), R331 (= R337)
- binding zinc ion: C38 (= C42), H61 (= H65), C92 (= C96), C95 (= C99), C98 (= C102), C106 (= C110), C148 (= C152)
1lluA The ternary complex of pseudomonas aeruginosa alcohol dehydrogenase with its coenzyme and weak substrate (see paper)
72% identity, 99% coverage: 1:342/344 of query aligns to 2:341/341 of 1lluA
- active site: C43 (= C42), H44 (= H43), T45 (= T44), H48 (= H47), H66 (= H65), E67 (= E66), C97 (= C96), C100 (= C99), C103 (= C102), C111 (= C110), Q115 (≠ L114), C153 (= C152), T157 (= T156), R336 (= R337)
- binding 1,2-ethanediol: H44 (= H43), T45 (= T44), L47 (= L46), D53 (= D52), W92 (= W91), C153 (= C152)
- binding nicotinamide-adenine-dinucleotide: C43 (= C42), H44 (= H43), T45 (= T44), H48 (= H47), C153 (= C152), T157 (= T156), G179 (= G178), G180 (= G179), L181 (= L180), D200 (= D199), I201 (= I200), K205 (= K204), A243 (= A244), V244 (= V245), S245 (= S246), A248 (= A249), V265 (≠ N266), L267 (= L268), I290 (= I291), V291 (= V292), R336 (= R337)
- binding zinc ion: C43 (= C42), H66 (= H65), C100 (= C99), C103 (= C102), C111 (= C110), C153 (= C152)
6n7lC Crystal structure of an alcohol dehydrogenase from elizabethkingia anophelis nuhp1
64% identity, 99% coverage: 3:342/344 of query aligns to 6:342/344 of 6n7lC
- active site: C45 (= C42), T47 (= T44), H50 (= H47), H68 (= H65), C154 (= C152)
- binding nicotinamide-adenine-dinucleotide: C45 (= C42), H46 (= H43), T47 (= T44), H50 (= H47), C154 (= C152), T158 (= T156), G178 (= G176), G180 (= G178), G181 (= G179), L182 (= L180), D201 (= D199), V202 (≠ I200), K206 (= K204), T243 (= T243), A244 (= A244), V245 (= V245), S246 (= S246), A249 (= A249), N266 (= N266), G267 (= G267), L268 (= L268), I291 (= I291), V292 (= V292)
- binding zinc ion: C45 (= C42), H68 (= H65), C98 (= C96), C101 (= C99), C104 (= C102), C112 (= C110), C154 (= C152)
P12311 Alcohol dehydrogenase; ADH-T; EC 1.1.1.1 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see paper)
60% identity, 98% coverage: 5:342/344 of query aligns to 1:336/337 of P12311
- C38 (= C42) mutation to S: No activity.
- T40 (= T44) mutation to A: No activity.; mutation to S: Little decrease in activity.
- H43 (= H47) mutation to A: No activity.; mutation to R: Higher level of activity at pH 9.
1rjwA Crystal structure of NAD(+)-dependent alcohol dehydrogenase from bacillus stearothermophilus strain lld-r (see paper)
60% identity, 98% coverage: 5:342/344 of query aligns to 1:336/339 of 1rjwA
- active site: C38 (= C42), H39 (= H43), T40 (= T44), H43 (= H47), H61 (= H65), E62 (= E66), C92 (= C96), C95 (= C99), C98 (= C102), C106 (= C110), K110 (≠ L114), C148 (= C152), T152 (= T156), R331 (= R337)
- binding trifluoroethanol: T40 (= T44), C148 (= C152), I285 (= I291)
- binding zinc ion: C38 (= C42), H61 (= H65), C92 (= C96), C95 (= C99), C98 (= C102), C106 (= C110)
3piiA Crystal structure of mutant of ht- alcohol dehydrogenase with substrate analogue butyramide
59% identity, 98% coverage: 5:342/344 of query aligns to 1:336/337 of 3piiA