SitesBLAST
Comparing WP_097030192.1 NCBI__GCF_900207575.1:WP_097030192.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1c7gA Tyrosine phenol-lyase from erwinia herbicola
38% identity, 93% coverage: 12:459/481 of query aligns to 4:453/456 of 1c7gA
- active site: Y71 (= Y79), F123 (= F131), T124 (= T132), D214 (= D222), T216 (≠ S224), K257 (= K265), R381 (= R388), F448 (= F454)
- binding pyridoxal-5'-phosphate: Q98 (= Q106), G99 (= G107), R100 (= R108), F123 (= F131), D214 (= D222), T216 (≠ S224), R217 (≠ L225), S254 (= S262), K257 (= K265)
6nv8B Perdeuterated tyrosine phenol-lyase from citrobacter freundii complexed with an aminoacrylate intermediate formed from s-ethyl-l- cysteine and 4-hydroxypyridine
38% identity, 93% coverage: 12:459/481 of query aligns to 3:452/455 of 6nv8B
- active site: Y70 (= Y79), F122 (= F131), T123 (= T132), D213 (= D222), T215 (≠ S224), K256 (= K265), R380 (= R388), F447 (= F454)
- binding pyridin-4-ol: S39 (≠ N48), K40 (≠ R49)
- binding 2-amino-acrylic acid: F122 (= F131), K256 (= K265), R403 (= R410)
2yctA Tyrosine phenol-lyase from citrobacter freundii in complex with pyridine n-oxide and the quinonoid intermediate formed with l-alanine (see paper)
38% identity, 93% coverage: 12:459/481 of query aligns to 3:452/455 of 2yctA
- active site: Y70 (= Y79), F122 (= F131), T123 (= T132), D213 (= D222), T215 (≠ S224), K256 (= K265), R380 (= R388), F447 (= F454)
- binding pyridine-n-oxide: S11 (≠ V20), W60 (≠ M69), R99 (= R108), F122 (= F131), T123 (= T132), M378 (= M386), R380 (= R388), F447 (= F454), F448 (= F455)
- binding (2e)-2-{[(z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1h)-ylidene}methyl]imino}propanoic acid: T48 (= T57), S50 (= S59), Q97 (= Q106), G98 (= G107), R99 (= R108), F122 (= F131), N184 (= N193), D213 (= D222), R216 (≠ L225), S253 (= S262), K256 (= K265), R403 (= R410)
- binding pyridoxal-5'-phosphate: Q97 (= Q106), G98 (= G107), R99 (= R108), F122 (= F131), D213 (= D222), R216 (≠ L225), S253 (= S262), K256 (= K265)
- binding phosphate ion: T48 (= T57), F122 (= F131), N184 (= N193), R403 (= R410)
2vlhA Quinonoid intermediate of citrobacter freundii tyrosine phenol-lyase formed with methionine (see paper)
38% identity, 93% coverage: 12:459/481 of query aligns to 4:453/456 of 2vlhA
- active site: Y71 (= Y79), F123 (= F131), T124 (= T132), D214 (= D222), T216 (≠ S224), K257 (= K265), R381 (= R388), F448 (= F454)
- binding (2e)-2-{[(z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1h)-ylidene}methyl]imino}-4-(methylsulfanyl)butanoic acid: T49 (= T57), Q98 (= Q106), G99 (= G107), R100 (= R108), F123 (= F131), N185 (= N193), D214 (= D222), R217 (≠ L225), S254 (= S262), K257 (= K265), R404 (= R410), F449 (= F455)
2vlfA Quinonoid intermediate of citrobacter freundii tyrosine phenol-lyase formed with alanine (see paper)
38% identity, 93% coverage: 12:459/481 of query aligns to 4:453/456 of 2vlfA
- active site: Y71 (= Y79), F123 (= F131), T124 (= T132), D214 (= D222), T216 (≠ S224), K257 (= K265), R381 (= R388), F448 (= F454)
- binding (2e)-2-{[(z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1h)-ylidene}methyl]imino}propanoic acid: T49 (= T57), Q98 (= Q106), G99 (= G107), R100 (= R108), F123 (= F131), N185 (= N193), D214 (= D222), T216 (≠ S224), R217 (≠ L225), S254 (= S262), K257 (= K265), R404 (= R410)
2ez2A Apo tyrosine phenol-lyase from citrobacter freundii at ph 8.0 (see paper)
38% identity, 93% coverage: 12:459/481 of query aligns to 4:453/456 of 2ez2A
- active site: Y71 (= Y79), F123 (= F131), T124 (= T132), D214 (= D222), T216 (≠ S224), K257 (= K265), R381 (= R388), F448 (= F454)
- binding phosphate ion: Q98 (= Q106), G99 (= G107), R100 (= R108), S254 (= S262), K257 (= K265)
2ycnA Y71f mutant of tyrosine phenol-lyase from citrobacter freundii in complex with quinonoid intermediate formed with 3-fluoro-l-tyrosine (see paper)
38% identity, 93% coverage: 12:459/481 of query aligns to 4:453/456 of 2ycnA
- active site: F71 (≠ Y79), F123 (= F131), T124 (= T132), D214 (= D222), T216 (≠ S224), K257 (= K265), R381 (= R388), F448 (= F454)
- binding (2E)-3-(3-fluoro-4-hydroxyphenyl)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}propanoic acid: T49 (= T57), Q98 (= Q106), G99 (= G107), R100 (= R108), F123 (= F131), T124 (= T132), T125 (= T133), N185 (= N193), D214 (= D222), R217 (≠ L225), S254 (= S262), K257 (= K265), M379 (= M386), R381 (= R388), R404 (= R410), F448 (= F454)
6mpdA Citrobacter freundii tyrosine phenol-lyase complexed with 4- hydroxypyridine and aminoacrylate from 3-f-l-tyrosine
38% identity, 93% coverage: 12:459/481 of query aligns to 3:452/455 of 6mpdA
- active site: Y70 (= Y79), F122 (= F131), T123 (= T132), D213 (= D222), T215 (≠ S224), K256 (= K265), R380 (= R388), F447 (= F454)
- binding 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid: T48 (= T57), Q97 (= Q106), G98 (= G107), R99 (= R108), F122 (= F131), N184 (= N193), D213 (= D222), R216 (≠ L225), S253 (= S262), K256 (= K265), R403 (= R410)
- binding pyridin-4-ol: R99 (= R108), F122 (= F131), T123 (= T132), Q227 (≠ R236), R322 (≠ A330), M378 (= M386), R380 (= R388), F447 (= F454), F448 (= F455)
- binding 3-fluorotyrosine: Y70 (= Y79), M287 (≠ F295)
6mo3B Citrobacter freundii tyrosine phenol-lyase complexed with 4- hydroxypyridine and aminoacrylate from l-serine
38% identity, 93% coverage: 12:459/481 of query aligns to 3:452/455 of 6mo3B
- active site: Y70 (= Y79), F122 (= F131), T123 (= T132), D213 (= D222), T215 (≠ S224), K256 (= K265), R380 (= R388), F447 (= F454)
- binding pyridin-4-ol: T14 (≠ K23), S39 (≠ N48), K40 (≠ R49)
- binding serine: T48 (= T57), S50 (= S59), F122 (= F131), K256 (= K265), R403 (= R410)
6mlsA Citrobacter freundii tyrosine phenol-lyase complexed with 4- hydroxypyridine and aminoacrylate from l-tyrosine
38% identity, 93% coverage: 12:459/481 of query aligns to 3:452/455 of 6mlsA