SitesBLAST
Comparing WP_101446957.1 NCBI__GCF_002846395.1:WP_101446957.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2gnaA Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-gal (see paper)
55% identity, 94% coverage: 5:325/341 of query aligns to 4:325/329 of 2gnaA
- binding galactose-uridine-5'-diphosphate: K87 (= K92), S176 (= S181), V177 (= V182), T195 (= T198), M199 (= M202), R201 (= R204), M235 (≠ I238), R254 (= R257), E257 (= E260)
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G13 (= G14), T15 (= T16), G16 (= G17), S17 (= S18), F18 (= F19), S39 (= S41), R40 (= R42), D41 (= D43), K44 (= K46), D63 (= D68), V64 (= V69), A83 (= A88), A84 (= A89), A85 (= A90), K87 (= K92), L125 (= L130), S126 (= S131), Y137 (= Y142), K141 (= K146), Y167 (= Y172), G168 (= G173), V170 (= V175)
2gn9A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glc (see paper)
55% identity, 94% coverage: 5:325/341 of query aligns to 4:325/329 of 2gn9A
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G13 (= G14), T15 (= T16), G16 (= G17), S17 (= S18), F18 (= F19), R40 (= R42), D41 (= D43), K44 (= K46), D63 (= D68), V64 (= V69), A83 (= A88), A84 (= A89), A85 (= A90), K87 (= K92), L125 (= L130), S126 (= S131), K141 (= K146), Y167 (= Y172), G168 (= G173), V170 (= V175), R174 (= R179)
- binding uridine-5'-diphosphate-glucose: K87 (= K92), T127 (= T132), K129 (= K134), Y137 (= Y142), N169 (= N174), S176 (= S181), V177 (= V182), P193 (= P196), T195 (= T198), M199 (= M202), R201 (= R204), M235 (≠ I238), R254 (= R257), E257 (= E260)
2gn6A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp-glcnac (see paper)
55% identity, 94% coverage: 5:325/341 of query aligns to 4:325/329 of 2gn6A
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G13 (= G14), T15 (= T16), G16 (= G17), S17 (= S18), F18 (= F19), R40 (= R42), D41 (= D43), K44 (= K46), D63 (= D68), V64 (= V69), A84 (= A89), A85 (= A90), K87 (= K92), S126 (= S131), Y137 (= Y142), K141 (= K146), Y167 (= Y172), G168 (= G173), V170 (= V175), S173 (= S178), R174 (= R179)
- binding uridine-diphosphate-n-acetylglucosamine: K87 (= K92), D128 (= D133), K129 (= K134), N169 (= N174), G175 (= G180), S176 (= S181), V177 (= V182), P193 (= P196), I194 (= I197), M199 (= M202), R201 (= R204), M235 (≠ I238), R254 (= R257), E257 (= E260)
2gn4A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADPH and udp-glcnac (see paper)
55% identity, 94% coverage: 5:325/341 of query aligns to 4:325/329 of 2gn4A
- binding nadph dihydro-nicotinamide-adenine-dinucleotide phosphate: G13 (= G14), T15 (= T16), G16 (= G17), S17 (= S18), F18 (= F19), S39 (= S41), R40 (= R42), D41 (= D43), K44 (= K46), D63 (= D68), V64 (= V69), A83 (= A88), A84 (= A89), A85 (= A90), K87 (= K92), T102 (= T107), L125 (= L130), S126 (= S131), T127 (= T132), Y137 (= Y142), K141 (= K146), Y167 (= Y172), G168 (= G173), V170 (= V175), S173 (= S178), R174 (= R179)
- binding uridine-diphosphate-n-acetylglucosamine: K87 (= K92), T127 (= T132), D128 (= D133), K129 (= K134), Y137 (= Y142), N169 (= N174), S176 (= S181), V177 (= V182), P193 (= P196), T195 (= T198), M199 (= M202), R201 (= R204), M235 (≠ I238), R254 (= R257), E257 (= E260)
2gn8A Crystal structure of udp-glcnac inverting 4,6-dehydratase in complex with NADP and udp (see paper)
55% identity, 94% coverage: 5:325/341 of query aligns to 2:323/327 of 2gn8A
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G11 (= G14), T13 (= T16), G14 (= G17), S15 (= S18), F16 (= F19), S37 (= S41), R38 (= R42), D39 (= D43), K42 (= K46), D61 (= D68), V62 (= V69), A81 (= A88), A82 (= A89), A83 (= A90), K85 (= K92), T100 (= T107), L123 (= L130), S124 (= S131), K139 (= K146), Y165 (= Y172), G166 (= G173), V168 (= V175), S171 (= S178), R172 (= R179)
- binding uridine-5'-diphosphate: K127 (= K134), N167 (= N174), V175 (= V182), P191 (= P196), I192 (= I197), T193 (= T198), M197 (= M202), R199 (= R204), M233 (≠ I238), R252 (= R257)
O25511 UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Pseudaminic acid biosynthesis protein B; UDP-GlcNAc-inverting 4,6-dehydratase; EC 4.2.1.115 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see paper)
55% identity, 94% coverage: 5:325/341 of query aligns to 8:329/333 of O25511
- TGSF 19:22 (= TGSF 16:19) binding NADP(+)
- SRDELK 43:48 (= SRDELK 41:46) binding NADP(+)
- DV 67:68 (= DV 68:69) binding NADP(+)
- A87 (= A88) binding NADP(+)
- K91 (= K92) binding NADP(+)
- LS 129:130 (= LS 130:131) binding NADP(+)
- K133 (= K134) mutation K->A,E: Loss of activity.
- Y141 (= Y142) binding NADP(+)
- K145 (= K146) binding NADP(+)
- VVGSR 174:178 (≠ VIGSR 175:179) binding NADP(+)
3w1vA Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with inihibitor (see paper)
39% identity, 96% coverage: 2:329/341 of query aligns to 8:333/347 of 3w1vA
- binding [(2R,3S,4R,5R,6R)-5-acetamido-6-[[[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,4-bis(oxidanyl)oxan-2-yl]methylimino-azanylidene-azanium: K93 (= K92), Q94 (= Q93), N175 (= N174), S179 (= S178), R180 (= R179), S182 (= S181), V183 (= V182), L186 (≠ F185), T198 (≠ P196), I199 (= I197), T200 (= T198), M204 (= M202), R206 (= R204), V240 (≠ I238), R263 (= R257), E266 (= E260)
4g5hA Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in complex with by-product (see paper)
39% identity, 96% coverage: 2:329/341 of query aligns to 8:333/346 of 4g5hA
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G20 (= G14), T22 (= T16), G23 (= G17), S24 (= S18), F25 (= F19), S45 (= S41), R46 (= R42), D47 (= D43), K50 (= K46), D69 (= D68), V70 (= V69), A89 (= A88), A90 (= A89), A91 (= A90), K93 (= K92), L131 (= L130), T133 (= T132), K147 (= K146), Y173 (= Y172)
- binding [(2R,3R,4R,6R)-3-acetamido-6-methyl-4-oxidanyl-5-oxidanylidene-oxan-2-yl] [[(2R,3S,4R,5R)-5-[2,4-bis(oxidanylidene)pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] hydrogen phosphate: Q94 (= Q93), V95 (= V94), K135 (= K134), N175 (= N174), S182 (= S181), V183 (= V182), L186 (≠ F185), T198 (≠ P196), T200 (= T198), M204 (= M202), V240 (≠ I238), R263 (= R257), E266 (= E260), Y278 (≠ S272), S313 (≠ G308), Y314 (≠ F309), E315 (≠ K310), Y316 (= Y311), N320 (= N316)
3vvcA Crystal structure of capsular polysaccharide synthesizing enzyme cape , k126e, in apo form (see paper)
39% identity, 96% coverage: 3:329/341 of query aligns to 1:305/318 of 3vvcA
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G12 (= G14), T14 (= T16), G15 (= G17), F17 (= F19), S37 (= S41), R38 (= R42), D39 (= D43), K42 (= K46), D61 (= D68), V62 (= V69), R63 (= R70), A81 (= A88), A82 (= A89), A83 (= A90), K85 (= K92), S124 (= S131), T125 (= T132), K139 (= K146), Y165 (= Y172), G166 (= G173)
4j2oC Crystal structure of NADP-bound wbjb from a. Baumannii community strain d1279779 (see paper)
44% identity, 81% coverage: 7:282/341 of query aligns to 4:280/316 of 4j2oC
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G11 (= G14), T13 (= T16), G14 (= G17), S15 (= S18), F16 (= F19), S36 (= S41), R37 (= R42), D38 (= D43), K41 (= K46), D60 (= D68), V61 (= V69), A80 (= A88), A81 (= A89), A82 (= A90), K84 (= K92), T99 (= T107), L122 (= L130), K138 (= K146), Y164 (= Y172)
6bwcC X-ray structure of pen from bacillus thuringiensis (see paper)
39% identity, 95% coverage: 7:329/341 of query aligns to 5:320/327 of 6bwcC
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G12 (= G14), T14 (= T16), G15 (= G17), T16 (≠ S18), I17 (≠ F19), S37 (= S41), R38 (= R42), S39 (≠ D43), D63 (= D68), I64 (≠ V69), V83 (≠ A88), A84 (= A89), K87 (= K92), T125 (≠ L130), S127 (≠ T132), Y137 (= Y142), K141 (= K146), F167 (≠ Y172), V170 (= V175), S173 (= S178), R174 (= R179)
- binding uridine-diphosphate-n-acetylglucosamine: K87 (= K92), H88 (≠ Q93), S127 (≠ T132), N128 (≠ D133), Y137 (= Y142), N169 (= N174), S176 (= S181), V177 (= V182), L180 (≠ F185), T192 (≠ P196), T194 (= T198), M198 (= M202), R200 (= R204), L234 (≠ I238), E265 (= E260)
3vvbA Crystal structure of capsular polysaccharide synthesizing enzyme cape from staphylococcus aureus in apo form (see paper)
35% identity, 95% coverage: 5:329/341 of query aligns to 1:260/270 of 3vvbA
- binding nadp nicotinamide-adenine-dinucleotide phosphate: G10 (= G14), T12 (= T16), G13 (= G17), S14 (= S18), F15 (= F19), S35 (= S41), R36 (= R42), D37 (= D43), K40 (= K46), D59 (= D68), V60 (= V69), A80 (= A89), A81 (= A90), K83 (= K92), L121 (= L130), T123 (= T132), K137 (= K146), Y163 (= Y172), G164 (= G173)
4tqgA Crystal structure of megavirus udp-glcnac 4,6-dehydratase, 5-epimerase mg534 (see paper)
34% identity, 86% coverage: 5:296/341 of query aligns to 3:276/297 of 4tqgA