SitesBLAST
Comparing WP_101588067.1 NCBI__GCF_900169175.1:WP_101588067.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3swoA Crystal structure of a glutaryl-coa dehydrogenase from mycobacterium smegmatis in complex with fadh2 (see paper)
60% identity, 98% coverage: 8:403/405 of query aligns to 3:387/388 of 3swoA
- active site: L135 (= L141), T136 (= T142), A246 (= A261), E367 (= E383), K379 (≠ R395)
- binding dihydroflavine-adenine dinucleotide: F133 (= F139), L135 (= L141), T136 (= T142), G141 (= G147), S142 (= S148), W166 (= W172), I167 (= I173), T168 (= T174), R272 (= R287), V274 (≠ Q289), F275 (= F290), L279 (= L294), Y282 (≠ F297), T340 (≠ A356), L341 (= L357), G344 (= G360), I347 (= I363), T365 (= T381), Y366 (= Y382), T369 (= T385), E371 (= E387), M372 (≠ V388)
3sf6A Crystal structure of glutaryl-coa dehydrogenase from mycobacterium smegmatis (see paper)
59% identity, 97% coverage: 12:403/405 of query aligns to 5:386/387 of 3sf6A
- active site: L134 (= L141), T135 (= T142), A245 (= A261), E366 (= E383), Q378 (≠ R395)
- binding dihydroflavine-adenine dinucleotide: F132 (= F139), L134 (= L141), T135 (= T142), G140 (= G147), S141 (= S148), W165 (= W172), I166 (= I173), T167 (= T174), S361 (≠ T378), T364 (= T381), Y365 (= Y382), T368 (= T385), E370 (= E387), M371 (≠ V388)
2ebaA Crystal structure of the putative glutaryl-coa dehydrogenase from thermus thermophilus
49% identity, 97% coverage: 13:403/405 of query aligns to 3:380/380 of 2ebaA
- active site: L131 (= L141), T132 (= T142), A239 (= A261), E360 (= E383), R372 (= R395)
- binding flavin-adenine dinucleotide: L131 (= L141), T132 (= T142), G136 (≠ V146), G137 (= G147), S138 (= S148), W161 (= W172), T163 (= T174), R265 (= R287), L272 (= L294), K275 (≠ F297), D333 (≠ A356), I334 (≠ L357), G337 (= G360), T355 (= T378), T358 (= T381), Y359 (= Y382), T362 (= T385)
2r0nA The effect of a glu370asp mutation in glutaryl-coa dehydrogenase on proton transfer to the dienolate intermediate (see paper)
50% identity, 86% coverage: 56:403/405 of query aligns to 48:388/390 of 2r0nA
- active site: L133 (= L141), T134 (= T142), A247 (= A261), E368 (= E383), R380 (= R395)
- binding flavin-adenine dinucleotide: F131 (= F139), L133 (= L141), T134 (= T142), G139 (= G147), S140 (= S148), W166 (= W172), I167 (= I173), T168 (= T174), Y367 (= Y382), T370 (= T385), D372 (≠ E387)
- binding 3-thiaglutaryl-CoA: R92 (= R100), S93 (= S101), V97 (= V105), P142 (= P150), G238 (≠ K252), F241 (≠ L255), L244 (= L258), N245 (≠ S259), P318 (= P333), Y367 (= Y382), E368 (= E383), I377 (≠ T392)
1sirA The crystal structure and mechanism of human glutaryl-coa dehydrogenase (see paper)
50% identity, 86% coverage: 56:403/405 of query aligns to 48:388/390 of 1sirA
- active site: L133 (= L141), T134 (= T142), A247 (= A261), E368 (= E383), R380 (= R395)
- binding flavin-adenine dinucleotide: F131 (= F139), L133 (= L141), T134 (= T142), G139 (= G147), S140 (= S148), W166 (= W172), I167 (= I173), T168 (= T174), Y367 (= Y382), T370 (= T385)
- binding s-4-nitrobutyryl-coa: S93 (= S101), S140 (= S148), F241 (≠ L255), G242 (≠ S256), L244 (= L258), N245 (≠ S259), R248 (= R262), P318 (= P333), Y367 (= Y382), E368 (= E383), R380 (= R395)
2r0mA The effect of a glu370asp mutation in glutaryl-coa dehydrogenase on proton transfer to the dienolate intermediate (see paper)
50% identity, 86% coverage: 56:403/405 of query aligns to 48:388/390 of 2r0mA
- active site: L133 (= L141), T134 (= T142), A247 (= A261), D368 (≠ E383), R380 (= R395)
- binding 4-nitrobutanoic acid: L101 (= L109), Y367 (= Y382), D368 (≠ E383)
- binding flavin-adenine dinucleotide: F131 (= F139), L133 (= L141), T134 (= T142), G139 (= G147), S140 (= S148), W166 (= W172), I167 (= I173), T168 (= T174), L210 (= L224), Y367 (= Y382), T370 (= T385)
3gqtC Crystal structure of glutaryl-coa dehydrogenase from burkholderia pseudomallei with fragment (1,4-dimethyl-1,2,3,4- tetrahydroquinoxalin-6-yl)methylamine (see paper)
47% identity, 84% coverage: 62:403/405 of query aligns to 55:385/385 of 3gqtC
- active site: L135 (= L141), T136 (= T142), A250 (= A261), E365 (= E383), R377 (= R395)
- binding 1-(1,4-dimethyl-1,2,3,4-tetrahydroquinoxalin-6-yl)methanamine: W166 (= W172), K210 (= K221), L213 (= L224), T218 (= T229), Y364 (= Y382)
3gncA Crystal structure of glutaryl-coa dehydrogenase from burkholderia pseudomallei with fragment 6421 (see paper)
46% identity, 84% coverage: 62:402/405 of query aligns to 56:380/380 of 3gncA
3eonC 2.55a crystal structure of native glutaryl-coa dehydrogenase from burkholderia pseudomallei in complex with a small molecule (see paper)
46% identity, 84% coverage: 62:402/405 of query aligns to 55:382/382 of 3eonC
3d6bC 2.2 a crystal structure of glutaryl-coa dehydrogenase from burkholderia pseudomallei (see paper)
45% identity, 84% coverage: 62:402/405 of query aligns to 55:377/377 of 3d6bC
2ix6A Short chain specific acyl-coa oxidase from arabidopsis thaliana, acx4 (see paper)
32% identity, 92% coverage: 32:403/405 of query aligns to 50:412/416 of 2ix6A
- active site: L158 (= L141), T159 (= T142), S271 (≠ A261), E392 (= E383), R404 (= R395)
- binding flavin-adenine dinucleotide: T159 (= T142), G164 (= G147), S165 (= S148), W189 (= W172), N239 (≠ T229), R297 (= R287), F300 (= F290), L304 (= L294), F307 (= F297), N310 (≠ S300), E365 (≠ A356), L366 (= L357), G369 (= G360), I372 (= I363), Y391 (= Y382), T394 (= T385), D396 (≠ E387)
Q96329 Acyl-coenzyme A oxidase 4, peroxisomal; AOX 4; G6p; Short-chain acyl-CoA oxidase; AtCX4; AtG6; SAOX; EC 1.3.3.6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
32% identity, 92% coverage: 32:403/405 of query aligns to 66:428/436 of Q96329
2ix5A Short chain specific acyl-coa oxidase from arabidopsis thaliana, acx4 in complex with acetoacetyl-coa (see paper)
32% identity, 92% coverage: 32:403/405 of query aligns to 50:412/415 of 2ix5A