Comparing WP_101589171.1 NCBI__GCF_900169175.1:WP_101589171.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
3ngjD Crystal structure of a putative deoxyribose-phosphate aldolase from entamoeba histolytica
45% identity, 95% coverage: 8:236/240 of query aligns to 8:219/222 of 3ngjD
Sites not aligning to the query:
Q4ZMV1 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Pseudomonas syringae pv. syringae (strain B728a) (see paper)
43% identity, 95% coverage: 8:235/240 of query aligns to 7:217/226 of Q4ZMV1
1ub3A Crystal structure of tetrameric structure of aldolase from thermus thermophilus hb8 (see paper)
41% identity, 95% coverage: 9:235/240 of query aligns to 1:210/211 of 1ub3A
Q9Y315 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Homo sapiens (Human) (see paper)
29% identity, 71% coverage: 42:211/240 of query aligns to 98:261/318 of Q9Y315
6z9iB Escherichia coli d-2-deoxyribose-5-phosphate aldolase - n21k mutant complex with reaction products (see paper)
28% identity, 86% coverage: 14:219/240 of query aligns to 13:214/248 of 6z9iB
Sites not aligning to the query:
P0A6L0 Deoxyribose-phosphate aldolase; DERA; 2-deoxy-D-ribose 5-phosphate aldolase; Phosphodeoxyriboaldolase; Deoxyriboaldolase; EC 4.1.2.4 from Escherichia coli (strain K12) (see 2 papers)
30% identity, 74% coverage: 42:219/240 of query aligns to 45:216/259 of P0A6L0
Sites not aligning to the query:
5el1A Crystal structure of deoxyribose-phosphate aldolase from escherichia coli (k58e-y96w mutant) after acetaldehyde treatment (see paper)
30% identity, 74% coverage: 42:219/240 of query aligns to 43:214/248 of 5el1A
Sites not aligning to the query:
5ekyA Crystal structure of deoxyribose-phosphate aldolase from escherichia coli (k58e-y96w mutant) (see paper)
30% identity, 74% coverage: 42:219/240 of query aligns to 43:214/248 of 5ekyA
Sites not aligning to the query:
1jcjA Observation of covalent intermediates in an enzyme mechanism at atomic resolution (see paper)
29% identity, 74% coverage: 42:219/240 of query aligns to 46:217/252 of 1jcjA
Sites not aligning to the query:
7p76A Re-engineered 2-deoxy-d-ribose-5-phosphate aldolase catalysing asymmetric michael addition reactions, schiff base complex with cinnamaldehyde (see paper)
30% identity, 74% coverage: 42:219/240 of query aligns to 42:213/247 of 7p76A
>WP_101589171.1 NCBI__GCF_900169175.1:WP_101589171.1
MTHAATAADLAARIDHTLLKPESSSSAFAGLVADARELGVLAVCVSPSALPLADTGGLVV
ATVCGFPSGAVQSSVKAAEAARAVADGAREVDMVVNLGLVKDGAWDLFEADVRGVVGAVA
AAAREQGLPEADGPEAAADGAAIVKVILESAALTDDEVVEACRRSEAAGAHYVKTSTGFH
PSGGASAHAVALMRETVGDRLGVKASGGIRTLEAAQQMLEAGASRLGLSGSKAILDQLAG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory