SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_106710062.1 NCBI__GCF_003010955.1:WP_106710062.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
34% identity, 90% coverage: 15:228/237 of query aligns to 11:212/214 of 4ymwC

query
sites
4ymwC
W
 
Y
G
 
T
P
 
P
S
 
L
I
 
F
A
 
I
S
 
S
G
 
G
I
 
L
L
 
I
V
 
M
T
 
T
V
 
L
S
 
K
L
 
L
A
 
T
L
 
F
A
 
L
T
 
A
L
 
V
P
 
T
L
 
I
G
 
G
L
 
V
A
 
L
V
 
M
G
 
G
F
 
L
F
 
F
V
 
I
A
 
A
L
 
L
G
 
M
K
 
K
Q
 
M
S
 
S
S
 
S
E
 
I
P
 
K
S
 
P
V
 
I
K
 
K
L
 
L
A
 
V
A
 
A
N
 
S
M
 
S
Y
 
Y
T
 
I
T
 
E
I
 
V
F
 
I
R
 
R
G
 
G
L
 
T
P
 
P
E
 
L
L
 
L
L
 
V
T
 
Q
L
 
L
F
 
L
L
 
L
V
 
I
Y
 
Y
F
 
N
G
 
G
G
 
-
Q
 
-
I
 
-
G
 
-
I
 
-
Q
 
-
K
 
-
L
 
L
G
 
M
Q
 
Q
L
 
-
F
 
F
G
 
G
Y
 
-
T
 
-
G
 
-
T
 
-
I
 
M
E
 
N
I
 
I
N
 
P
S
 
A
F
 
F
I
 
T
A
 
A
G
 
G
M
 
V
F
 
S
A
 
A
M
 
L
G
 
A
T
 
I
V
x
N
F
 
S
S
 
S
S
 
A
Y
|
Y
A
 
V
S
 
A
E
 
E
V
 
I
F
 
I
L
 
R
S
 
A
A
 
G
F
 
I
R
 
Q
A
 
A
I
 
V
P
 
D
K
 
P
G
 
G
Q
 
Q
Y
 
N
E
 
E
G
 
A
G
 
A
Y
 
R
A
 
S
I
 
L
G
 
G
L
 
M
S
 
T
N
 
H
G
 
A
Q
 
M
T
 
A
M
 
M
R
 
R
K
 
Y
V
 
V
I
 
I
L
 
I
P
 
P
Q
 
Q
L
 
A
I
 
I
R
 
K
I
 
N
A
 
I
L
 
L
P
 
P
G
 
A
L
 
L
G
 
G
N
 
N
L
x
E
W
 
F
M
 
I
I
 
V
L
 
M
L
 
L
K
 
K
D
x
E
T
 
S
A
 
A
L
 
I
V
 
V
S
 
S
A
 
V
I
 
I
G
 
G
L
 
F
A
 
A
D
 
D
I
 
L
L
 
T
R
 
R
Q
 
Q
T
 
A
A
 
D
V
 
I
A
 
I
A
 
Q
R
 
S
V
 
V
T
 
T
K
 
Y
H
 
R
A
 
Y
F
 
F
L
 
E
F
 
P
Y
 
Y
G
 
I
T
 
I
A
 
I
C
 
A
M
 
A
I
 
I
Y
 
Y
L
 
F
A
 
V
L
 
M
A
 
T
I
 
L
L
 
T
S
 
F
S
 
S
F
 
K
V
 
L
I
 
L
D
 
S
G
 
L
I
 
F
D
 
E
R
 
R

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
34% identity, 90% coverage: 15:228/237 of query aligns to 11:212/215 of 4ymtC

query
sites
4ymtC
W
 
Y
G
 
T
P
 
P
S
 
L
I
 
F
A
 
I
S
 
S
G
 
G
I
 
L
L
 
I
V
 
M
T
 
T
V
 
L
S
 
K
L
 
L
A
 
T
L
 
F
A
 
L
T
 
A
L
 
V
P
 
T
L
 
I
G
 
G
L
 
V
A
 
L
V
 
M
G
 
G
F
 
L
F
 
F
V
 
I
A
 
A
L
 
L
G
 
M
K
 
K
Q
 
M
S
 
S
S
 
S
E
 
I
P
 
K
S
 
P
V
 
I
K
 
K
L
 
L
A
 
V
A
 
A
N
 
S
M
 
S
Y
 
Y
T
 
I
T
 
E
I
 
V
F
 
I
R
 
R
G
 
G
L
 
T
P
|
P
E
x
L
L
 
L
L
 
V
T
 
Q
L
 
L
F
 
L
L
 
L
V
 
I
Y
 
Y
F
 
N
G
 
G
G
 
-
Q
 
-
I
 
-
G
 
-
I
 
-
Q
 
-
K
 
-
L
 
L
G
 
M
Q
 
Q
L
 
-
F
 
F
G
 
G
Y
 
-
T
 
-
G
 
-
T
 
-
I
 
M
E
 
N
I
 
I
N
 
P
S
 
A
F
 
F
I
 
T
A
 
A
G
 
G
M
 
V
F
 
S
A
 
A
M
 
L
G
 
A
T
 
I
V
x
N
F
 
S
S
 
S
S
 
A
Y
|
Y
A
 
V
S
 
A
E
 
E
V
 
I
F
 
I
L
 
R
S
 
A
A
 
G
F
 
I
R
 
Q
A
 
A
I
 
V
P
 
D
K
 
P
G
 
G
Q
 
Q
Y
 
N
E
 
E
G
 
A
G
 
A
Y
 
R
A
 
S
I
 
L
G
 
G
L
 
M
S
 
T
N
 
H
G
 
A
Q
 
M
T
 
A
M
 
M
R
 
R
K
 
Y
V
 
V
I
 
I
L
 
I
P
 
P
Q
 
Q
L
 
A
I
 
I
R
 
K
I
 
N
A
 
I
L
 
L
P
 
P
G
 
A
L
 
L
G
 
G
N
 
N
L
x
E
W
 
F
M
 
I
I
 
V
L
x
M
L
 
L
K
|
K
D
x
E
T
 
S
A
 
A
L
 
I
V
 
V
S
 
S
A
 
V
I
 
I
G
 
G
L
 
F
A
 
A
D
 
D
I
 
L
L
 
T
R
 
R
Q
 
Q
T
 
A
A
 
D
V
 
I
A
 
I
A
 
Q
R
 
S
V
 
V
T
 
T
K
 
Y
H
 
R
A
 
Y
F
 
F
L
 
E
F
 
P
Y
 
Y
G
 
I
T
 
I
A
 
I
C
 
A
M
 
A
I
 
I
Y
 
Y
L
 
F
A
 
V
L
 
M
A
 
T
I
 
L
L
 
T
S
 
F
S
 
S
F
 
K
V
 
L
I
 
L
D
 
S
G
 
L
I
 
F
D
 
E
R
 
R

Query Sequence

>WP_106710062.1 NCBI__GCF_003010955.1:WP_106710062.1
MEGSIALLGFGEGGWGPSIASGILVTVSLALATLPLGLAVGFFVALGKQSSEPSVKLAAN
MYTTIFRGLPELLTLFLVYFGGQIGIQKLGQLFGYTGTIEINSFIAGMFAMGTVFSSYAS
EVFLSAFRAIPKGQYEGGYAIGLSNGQTMRKVILPQLIRIALPGLGNLWMILLKDTALVS
AIGLADILRQTAVAARVTKHAFLFYGTACMIYLALAILSSFVIDGIDRWAAKSGVKR

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory