SitesBLAST
Comparing WP_110206972.1 NCBI__GCF_003194585.1:WP_110206972.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8e9hF Mycobacterial respiratory complex i, fully-inserted quinone (see paper)
71% identity, 96% coverage: 14:446/453 of query aligns to 1:436/436 of 8e9hF
- binding flavin mononucleotide: G53 (= G67), R54 (= R68), G55 (= G69), A57 (= A71), K64 (= K78), N90 (= N95), D92 (= D97), Y178 (= Y183), G181 (= G186), E182 (= E187), E183 (= E188), N217 (= N222), N218 (= N223), S221 (= S226), L398 (= L407)
- binding iron/sulfur cluster: P197 (= P202), S349 (= S354), C350 (= C355), G351 (= G356), K352 (= K357), C353 (= C358), C356 (= C361), S394 (≠ A403), F395 (= F404), C396 (= C405), L398 (= L407), G399 (= G408)
- binding zinc ion: C333 (= C338), E371 (= E376), H420 (= H429), C425 (= C435)
Q56222 NADH-quinone oxidoreductase subunit 1; NADH dehydrogenase I chain 1; NDH-1 subunit 1; EC 7.1.1.- from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
52% identity, 89% coverage: 27:428/453 of query aligns to 24:423/438 of Q56222
- K75 (= K78) binding FMN
- NADES 92:96 (= NADES 95:99) binding FMN
- YICGEE 180:185 (= YICGEE 183:188) binding FMN
- INN 218:220 (= INN 221:223) binding FMN
- C353 (= C355) binding [4Fe-4S] cluster
- C356 (= C358) binding [4Fe-4S] cluster
- C359 (= C361) binding [4Fe-4S] cluster
- C400 (= C405) binding [4Fe-4S] cluster
4hea1 Crystal structure of the entire respiratory complex i from thermus thermophilus (see paper)
52% identity, 89% coverage: 27:428/453 of query aligns to 23:422/437 of 4hea1
- binding flavin mononucleotide: G63 (= G67), K74 (= K78), N91 (= N95), D93 (= D97), Y179 (= Y183), G182 (= G186), E183 (= E187), N218 (= N222), N219 (= N223), L401 (= L407)
- binding iron/sulfur cluster: I180 (= I184), P198 (= P202), S351 (= S354), C352 (= C355), G353 (= G356), K354 (= K357), C355 (= C358), C358 (= C361), F398 (= F404), C399 (= C405), L401 (= L407)
2ybb1 Fitted model for bovine mitochondrial supercomplex i1iii2iv1 by single particle cryo-em (emd-1876) (see paper)
52% identity, 89% coverage: 27:428/453 of query aligns to 23:422/437 of 2ybb1
- binding flavin mononucleotide: G63 (= G67), G65 (= G69), N91 (= N95), D93 (= D97), G182 (= G186), E183 (= E187), E184 (= E188), N218 (= N222), N219 (= N223), T222 (≠ S226), P400 (≠ A406)
- binding 1,4-dihydronicotinamide adenine dinucleotide: G65 (= G69), G66 (= G70), F69 (= F73), K74 (= K78), F77 (= F81), E96 (= E100), Y179 (= Y183), E184 (= E188), K201 (≠ R205), F204 (= F208), T324 (= T327)
- binding iron/sulfur cluster: S351 (= S354), C352 (= C355), K354 (= K357), C355 (= C358), C358 (= C361), F398 (= F404), C399 (= C405), L401 (= L407), A402 (≠ G408)
7p61F Complex i from e. Coli, ddm-purified, with nadh, resting state (see paper)
49% identity, 89% coverage: 25:428/453 of query aligns to 20:421/442 of 7p61F
- binding flavin mononucleotide: G61 (= G67), G63 (= G69), K72 (= K78), N90 (= N95), D92 (= D97), G181 (= G186), E182 (= E187), N217 (= N222), N218 (= N223), A399 (= A406), H400 (≠ L407)
- binding 1,4-dihydronicotinamide adenine dinucleotide: G63 (= G69), G64 (= G70), A65 (= A71), F67 (= F73), K72 (= K78), L75 (≠ F81), E95 (= E100), Y178 (= Y183), E183 (= E188), F203 (= F208), R320 (≠ M324), T323 (= T327)
- binding iron/sulfur cluster: S350 (= S354), C351 (= C355), W353 (≠ K357), C354 (= C358), C357 (= C361), F397 (= F404), C398 (= C405), H400 (≠ L407)
8qbyF Respiratory complex i from paracoccus denitrificans in msp2n2 nanodiscs
51% identity, 82% coverage: 54:425/453 of query aligns to 41:412/421 of 8qbyF
- binding flavin mononucleotide: G54 (= G67), R55 (= R68), G56 (= G69), K65 (= K78), N83 (= N95), E86 (= E98), Y171 (= Y183), G174 (= G186), E175 (= E187), V209 (≠ I221), N210 (= N222), N211 (= N223), S214 (= S226)
- binding iron/sulfur cluster: I172 (= I184), P190 (= P202), C346 (= C355), G347 (= G356), Q348 (≠ K357), C349 (= C358), C352 (= C361), T390 (≠ A403), C392 (= C405), L394 (= L407), G395 (= G408)
7t30B Structure of electron bifurcating ni-fe hydrogenase complex hydabcsl in fmn/NAD(h) bound state (see paper)
48% identity, 89% coverage: 32:436/453 of query aligns to 19:420/425 of 7t30B
- binding fe2/s2 (inorganic) cluster: C326 (= C338), C364 (≠ E376), H413 (= H429), C419 (= C435)
- binding flavin mononucleotide: G54 (= G67), G56 (= G69), K65 (= K78), N82 (= N95), D84 (= D97), E85 (= E98), G173 (= G186), E175 (= E188), N210 (= N223), G390 (≠ A406), L391 (= L407)
- binding nicotinamide-adenine-dinucleotide: G56 (= G69), G57 (= G70), A58 (= A71), F60 (= F73), K65 (= K78), F68 (= F81), E85 (= E98), E175 (= E188), R192 (= R205), F195 (= F208), I312 (≠ M324), M313 (≠ L325), S315 (≠ T327)
- binding iron/sulfur cluster: S342 (= S354), C343 (= C355), G344 (= G356), C346 (= C358), C349 (= C361), S387 (≠ A403), C389 (= C405), L391 (= L407), G392 (= G408)
Sites not aligning to the query:
7t2rB Structure of electron bifurcating ni-fe hydrogenase complex hydabcsl in fmn-free apo state (see paper)
48% identity, 89% coverage: 32:436/453 of query aligns to 19:420/425 of 7t2rB
- binding fe2/s2 (inorganic) cluster: C326 (= C338), D329 (≠ R341), C364 (≠ E376), H413 (= H429), C419 (= C435)
- binding iron/sulfur cluster: P189 (= P202), C343 (= C355), G344 (= G356), C346 (= C358), C349 (= C361), C389 (= C405), G392 (= G408)
Sites not aligning to the query:
7arcF Cryo-em structure of polytomella complex-i (peripheral arm) (see paper)
49% identity, 82% coverage: 54:425/453 of query aligns to 48:419/430 of 7arcF
- binding flavin mononucleotide: G61 (= G67), R62 (= R68), K72 (= K78), N90 (= N95), D92 (= D97), E93 (= E98), S94 (= S99), Y178 (= Y183), G181 (= G186), E182 (= E187), T217 (≠ N222), N218 (= N223), L401 (= L407)
- binding iron/sulfur cluster: S352 (= S354), C353 (= C355), G354 (= G356), Q355 (≠ K357), C356 (= C358), C359 (= C361), T397 (≠ A403), C399 (= C405), L401 (= L407)
7aqrF Cryo-em structure of arabidopsis thaliana complex-i (peripheral arm) (see paper)
49% identity, 81% coverage: 54:422/453 of query aligns to 47:415/434 of 7aqrF
- binding flavin mononucleotide: G60 (= G67), R61 (= R68), G62 (= G69), K71 (= K78), N89 (= N95), D91 (= D97), Y177 (= Y183), G180 (= G186), E181 (= E187), E182 (= E188), T216 (≠ N222), N217 (= N223)
- binding iron/sulfur cluster: S351 (= S354), C352 (= C355), G353 (= G356), Q354 (≠ K357), C355 (= C358), C358 (= C361), T396 (≠ A403), C398 (= C405), L400 (= L407)
7v2cA Active state complex i from q10 dataset (see paper)
46% identity, 89% coverage: 23:425/453 of query aligns to 19:420/433 of 7v2cA