Comparing WP_110207096.1 NCBI__GCF_003194585.1:WP_110207096.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
1e19A Structure of the carbamate kinase-like carbamoyl phosphate synthetase from the hyperthermophilic archaeon pyrococcus furiosus bound to adp (see paper)
40% identity, 96% coverage: 6:311/318 of query aligns to 5:313/313 of 1e19A
4jz8A Carbamate kinase from giardia lamblia bound to citric acid (see paper)
40% identity, 97% coverage: 3:310/318 of query aligns to 5:314/316 of 4jz8A
4jz7C Carbamate kinase from giardia lamblia bound to amp-pnp (see paper)
40% identity, 97% coverage: 3:310/318 of query aligns to 5:314/316 of 4jz7C
P0A2X8 Carbamate kinase 1; EC 2.7.2.2 from Enterococcus faecium (Streptococcus faecium) (see 2 papers)
43% identity, 93% coverage: 1:295/318 of query aligns to 1:295/310 of P0A2X8
2we5A Carbamate kinase from enterococcus faecalis bound to mgadp (see paper)
43% identity, 91% coverage: 6:295/318 of query aligns to 5:294/309 of 2we5A
2we4A Carbamate kinase from enterococcus faecalis bound to a sulfate ion and two water molecules, which mimic the substrate carbamyl phosphate (see paper)
43% identity, 91% coverage: 6:295/318 of query aligns to 5:294/309 of 2we4A
Sites not aligning to the query:
4olcA Carbamate kinase from giardia lamblia thiocarbamoylated by disulfiram on cys242 (see paper)
39% identity, 97% coverage: 3:310/318 of query aligns to 4:306/308 of 4olcA
4jz7A Carbamate kinase from giardia lamblia bound to amp-pnp (see paper)
35% identity, 97% coverage: 3:310/318 of query aligns to 5:283/285 of 4jz7A
8crvA Crystal structure of the carbamate kinase from pseudomonas aeruginosa
42% identity, 90% coverage: 6:291/318 of query aligns to 6:286/312 of 8crvA
4axsA Structure of carbamate kinase from mycoplasma penetrans (see paper)
34% identity, 96% coverage: 6:310/318 of query aligns to 3:290/291 of 4axsA
>WP_110207096.1 NCBI__GCF_003194585.1:WP_110207096.1
MSRIAVVAVGGNALTREHEIGTSEQIEANAHAMAQGIARLHADGWRVVVVHGNGPQVGNL
SIQQEESVGLVPPQPLASVNAMTQGQLGSVLVRALDALLGAGTAVAVVSHMVVDPDDPAF
VDPTKPIGPFFSAGRAEQLAEERGWVMREDAGRGFRRVVASPRPVELLESAAIRTLVERS
HVVLACGGGGIGVLGGVDDGYPGVDAVIDKDAAAASVAISLRADGLILVTGVDAVSINYG
TPEQTVVHELGVDAAIRYLGDGQFPPGSMGPKVRSAIDFVQAGGSAAVITSAEHLHDAID
PTTTFGTRIVPSSVMSSL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory