Comparing WP_110803698.1 NCBI__GCF_003217355.1:WP_110803698.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
4ehuA Activator of the 2-hydroxyisocaproyl-coa dehydratase from clostridium difficile with bound adpnp (see paper)
45% identity, 90% coverage: 20:273/283 of query aligns to 3:252/268 of 4ehuA
4ehtA Activator of the 2-hydroxyisocaproyl-coa dehydratase from clostridium difficile with bound adp (see paper)
45% identity, 90% coverage: 20:273/283 of query aligns to 3:252/268 of 4ehtA
Q5U925 2-hydroxyisocaproyl-CoA dehydratase activator; EC 3.-.-.- from Clostridioides difficile (Peptoclostridium difficile) (see paper)
45% identity, 90% coverage: 20:273/283 of query aligns to 3:252/266 of Q5U925
P11568 (R)-2-hydroxyglutaryl-CoA dehydratase activating ATPase; (R)-2-hydroxyglutaryl-CoA dehydratase activase; (R)-2-hydroxyglutaryl-CoA dehydratase, component A; ATP-coupled electron transfer protein HgdC; Activator of (R)-2-hydroxyglutaryl-CoA dehydratase; EC 3.6.1.- from Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) (see 2 papers)
43% identity, 88% coverage: 20:268/283 of query aligns to 5:249/260 of P11568
Sites not aligning to the query:
1huxA Crystal structure of the acidaminococcus fermentans (r)-2- hydroxyglutaryl-coa dehydratase component a (see paper)
43% identity, 88% coverage: 20:268/283 of query aligns to 4:248/259 of 1huxA
7yzqE Mgadp-alf4-bound dccp:dccp-r complex (see paper)
38% identity, 90% coverage: 22:275/283 of query aligns to 4:242/243 of 7yzqE
7yzmE Mgadpnp-bound dccp:dccp-r complex (see paper)
38% identity, 90% coverage: 22:275/283 of query aligns to 4:242/243 of 7yzmE
7yylE Nucleotide-free dccp:dccp-r complex (see paper)
38% identity, 90% coverage: 22:275/283 of query aligns to 4:242/243 of 7yylE
>WP_110803698.1 NCBI__GCF_003217355.1:WP_110803698.1
MQVAQAIADDRIGDLRKTPTIGIDIGSRQAKAVLLDDAEVHTVITASGVDAQDTADRLVK
KLLRQSGRDRADIAYVVGTGYGRIALGYDDIPTQIVTEISCHAMGAHFLNAGTRSIIDIG
GQDSKAIKVDPDTGRVREFVMNDKCAAGTGRFLEKIAELLDYRLDELGDRALEAEERATI
SSQCVVFAESEVISLKVRGTRREDIAAGIHYASARRVRNLVNRIGLDPEIVFTGGVSNNK
GMKRALEDLIGAPISETKLDTTYAGALGAAVIAQQYYDGALVQ
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory