SitesBLAST
Comparing WP_110803821.1 NCBI__GCF_003217355.1:WP_110803821.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
4amvA E.Coli glucosamine-6p synthase in complex with fructose-6p (see paper)
48% identity, 100% coverage: 2:603/603 of query aligns to 1:608/608 of 4amvA
- active site: C1 (= C2), R26 (= R27), G27 (= G28), W74 (= W74), N98 (= N98), G99 (= G99), Y248 (= Y248), E481 (= E476), K485 (= K480), E488 (= E483), H504 (= H499), K603 (= K598)
- binding fructose -6-phosphate: G301 (= G296), T302 (= T297), S303 (≠ A298), S347 (= S342), Q348 (= Q343), S349 (= S344), T352 (= T347), S401 (= S395), K485 (= K480), E488 (= E483)
1jxaA Glucosamine 6-phosphate synthase with glucose 6-phosphate (see paper)
48% identity, 100% coverage: 2:603/603 of query aligns to 1:608/608 of 1jxaA
- active site: C1 (= C2), R26 (= R27), G27 (= G28), W74 (= W74), N98 (= N98), G99 (= G99), Y248 (= Y248), E481 (= E476), K485 (= K480), E488 (= E483), H504 (= H499), K603 (= K598)
- binding glucose-6-phosphate: T302 (= T297), S303 (≠ A298), S347 (= S342), Q348 (= Q343), S349 (= S344), T352 (= T347), S401 (= S395), K485 (= K480), E488 (= E483)
2j6hA E. Coli glucosamine-6-p synthase in complex with glucose-6p and 5-oxo- l-norleucine (see paper)
48% identity, 100% coverage: 2:603/603 of query aligns to 1:608/608 of 2j6hA
- active site: C1 (= C2), R26 (= R27), G27 (= G28), W74 (= W74), N98 (= N98), G99 (= G99), Y248 (= Y248), E481 (= E476), K485 (= K480), E488 (= E483), H504 (= H499), K603 (= K598)
- binding glucose-6-phosphate: T302 (= T297), S347 (= S342), Q348 (= Q343), S349 (= S344), T352 (= T347), V399 (= V393), S401 (= S395), E488 (= E483)
- binding 5-oxo-l-norleucine: C1 (= C2), R73 (= R73), W74 (= W74), T76 (= T76), H86 (= H86), N98 (= N98), G99 (= G99), D123 (= D123)
6svmA Crystal structure of human gfat-1 in complex with glucose-6-phosphate, l-glu, and udp-galnac (see paper)
36% identity, 100% coverage: 2:603/603 of query aligns to 1:660/660 of 6svmA
- active site: L7 (= L8), R32 (= R27), W95 (= W74), N122 (= N98), G123 (= G99), E533 (= E476), K537 (= K480), E540 (= E483), H556 (= H499), K655 (= K598)
- binding glucose-6-phosphate: C353 (= C295), T355 (= T297), S356 (≠ A298), S400 (= S342), Q401 (= Q343), S402 (= S344), T405 (= T347), S453 (= S395), K537 (= K480), E540 (= E483)
- binding glutamic acid: C1 (= C2), R94 (= R73), W95 (= W74), T97 (= T76), H107 (= H86), G123 (= G99), D147 (= D123)
- binding magnesium ion: S434 (≠ A376), R435 (= R377), T437 (≠ C379)
- binding uridine-diphosphate-n-acetylgalactosamine: Q289 (≠ D237), R322 (≠ Y270), G334 (≠ A280), G424 (≠ A366), T426 (≠ V368), S434 (≠ A376), T437 (≠ C379), C439 (≠ L381), G440 (≠ A382), V441 (≠ L383), H442 (≠ P384)
6r4eA Crystal structure of human gfat-1 in complex with glucose-6-phosphate and l-glu (see paper)
36% identity, 100% coverage: 2:603/603 of query aligns to 1:663/663 of 6r4eA
- active site: L7 (= L8), R32 (= R27), W95 (= W74), N122 (= N98), G123 (= G99), E536 (= E476), K540 (= K480), E543 (= E483), H559 (= H499), K658 (= K598)
- binding glucose-6-phosphate: T358 (= T297), S359 (≠ A298), S403 (= S342), Q404 (= Q343), S405 (= S344), T408 (= T347), S456 (= S395), K540 (= K480), E543 (= E483)
- binding glutamic acid: C1 (= C2), R94 (= R73), W95 (= W74), T97 (= T76), G123 (= G99), D147 (= D123)
6r4gA Crystal structure of human gfat-1 in complex with udp-glcnac (see paper)
35% identity, 99% coverage: 2:596/603 of query aligns to 1:652/652 of 6r4gA
- active site: L7 (= L8), R32 (= R27), W95 (= W74), N122 (= N98), G123 (= G99), E532 (= E476), K536 (= K480), E539 (= E483), H555 (= H499)
- binding glucose-6-phosphate: G353 (= G296), T354 (= T297), S355 (≠ A298), S399 (= S342), Q400 (= Q343), S401 (= S344), T404 (= T347), S452 (= S395), E539 (= E483)
- binding magnesium ion: S433 (≠ A376), R434 (= R377), T436 (≠ C379)
- binding uridine-diphosphate-n-acetylglucosamine: Q288 (≠ D237), R321 (≠ Y270), G333 (≠ A280), G423 (≠ A366), T425 (≠ V368), S433 (≠ A376), T436 (≠ C379), C438 (≠ L381), G439 (≠ A382), V440 (≠ L383), H441 (≠ P384)
Q06210 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; D-fructose-6-phosphate amidotransferase 1; Glutamine:fructose-6-phosphate amidotransferase 1; GFAT 1; GFAT1; Hexosephosphate aminotransferase 1; EC 2.6.1.16 from Homo sapiens (Human) (see paper)
34% identity, 100% coverage: 1:603/603 of query aligns to 1:699/699 of Q06210