SitesBLAST – Find functional sites

 

SitesBLAST

Comparing WP_157520500.1 NCBI__GCF_001653335.1:WP_157520500.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
34% identity, 71% coverage: 61:240/255 of query aligns to 35:208/214 of 4ymwC

query
sites
4ymwC
V
 
L
V
 
M
G
 
G
L
 
L
A
 
F
L
 
I
A
 
A
V
 
L
M
 
M
R
 
K
L
 
M
L
 
-
P
 
-
G
 
-
R
 
S
A
 
S
G
 
I
R
 
K
P
 
P
L
 
I
R
 
K
W
 
L
I
 
V
A
 
A
T
 
S
L
 
S
Y
 
Y
V
 
I
D
 
E
V
 
V
F
 
I
R
 
R
A
 
G
I
 
T
P
 
P
S
 
L
I
 
L
I
 
V
V
 
Q
L
 
L
Y
 
L
L
 
L
V
 
I
G
 
Y
F
 
N
G
 
G
L
 
L
S
 
M
L
 
Q
A
 
F
Q
 
G
V
 
M
P
 
N
I
 
I
V
 
-
R
 
-
D
 
-
F
 
-
S
 
-
P
 
P
L
 
A
W
 
F
L
 
T
A
 
A
-
 
G
I
 
V
L
 
S
A
 
A
L
 
L
T
 
A
L
 
I
T
x
N
Y
 
S
S
 
S
A
 
A
Y
|
Y
V
 
V
A
 
A
E
 
E
V
 
I
Y
 
I
R
 
R
A
 
A
G
 
G
I
 
I
D
 
Q
S
 
A
I
 
V
H
 
D
P
 
P
S
 
G
Q
 
Q
W
 
N
S
 
E
A
 
A
S
 
A
R
 
R
S
 
S
L
 
L
G
 
G
L
 
M
S
 
T
Y
 
H
S
 
A
M
 
M
T
 
A
L
 
M
R
 
R
T
 
Y
V
 
V
I
 
I
V
 
I
P
 
P
Q
 
Q
A
 
A
V
 
I
R
 
K
R
 
N
I
 
I
V
 
L
P
 
P
P
 
A
L
 
L
L
 
G
N
 
N
D
x
E
F
 
F
I
 
I
G
 
V
L
 
M
Q
 
L
K
 
K
D
x
E
T
 
S
A
 
A
L
 
I
I
 
V
G
 
S
V
 
V
M
 
I
G
 
G
V
 
F
T
 
A
D
 
D
A
 
L
F
 
T
M
 
R
Q
 
Q
A
 
A
R
 
D
L
 
I
V
 
I
S
 
Q
S
 
S
N
 
V
V
 
T
F
 
Y
N
 
R
-
 
Y
L
 
F
T
 
E
P
 
P
V
 
Y
I
 
I
V
 
I
V
 
I
A
 
A
V
 
A
L
 
I
F
 
Y
V
 
F
I
 
V
I
 
M
T
 
T
I
 
L
P
 
T
Q
 
F
A
 
S
R
 
K
F
 
L
V
 
L
D
 
S

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
34% identity, 71% coverage: 61:240/255 of query aligns to 35:208/215 of 4ymtC

query
sites
4ymtC
V
 
L
V
 
M
G
 
G
L
 
L
A
 
F
L
 
I
A
 
A
V
 
L
M
 
M
R
 
K
L
 
M
L
 
-
P
 
-
G
 
-
R
 
S
A
 
S
G
 
I
R
 
K
P
 
P
L
 
I
R
 
K
W
 
L
I
 
V
A
 
A
T
 
S
L
 
S
Y
 
Y
V
 
I
D
 
E
V
 
V
F
 
I
R
 
R
A
 
G
I
 
T
P
|
P
S
x
L
I
 
L
I
 
V
V
 
Q
L
 
L
Y
 
L
L
 
L
V
 
I
G
 
Y
F
 
N
G
 
G
L
 
L
S
 
M
L
 
Q
A
 
F
Q
 
G
V
 
M
P
 
N
I
 
I
V
 
-
R
 
-
D
 
-
F
 
-
S
 
-
P
 
P
L
 
A
W
 
F
L
 
T
A
 
A
-
 
G
I
 
V
L
 
S
A
 
A
L
 
L
T
 
A
L
 
I
T
x
N
Y
 
S
S
 
S
A
 
A
Y
|
Y
V
 
V
A
 
A
E
 
E
V
 
I
Y
 
I
R
 
R
A
 
A
G
 
G
I
 
I
D
 
Q
S
 
A
I
 
V
H
 
D
P
 
P
S
 
G
Q
 
Q
W
 
N
S
 
E
A
 
A
S
 
A
R
 
R
S
 
S
L
 
L
G
 
G
L
 
M
S
 
T
Y
 
H
S
 
A
M
 
M
T
 
A
L
 
M
R
 
R
T
 
Y
V
 
V
I
 
I
V
 
I
P
 
P
Q
 
Q
A
 
A
V
 
I
R
 
K
R
 
N
I
 
I
V
 
L
P
 
P
P
 
A
L
 
L
L
 
G
N
 
N
D
x
E
F
 
F
I
 
I
G
 
V
L
x
M
Q
 
L
K
|
K
D
x
E
T
 
S
A
 
A
L
 
I
I
 
V
G
 
S
V
 
V
M
 
I
G
 
G
V
 
F
T
 
A
D
 
D
A
 
L
F
 
T
M
 
R
Q
 
Q
A
 
A
R
 
D
L
 
I
V
 
I
S
 
Q
S
 
S
N
 
V
V
 
T
F
 
Y
N
 
R
-
 
Y
L
 
F
T
 
E
P
 
P
V
 
Y
I
 
I
V
 
I
V
 
I
A
 
A
V
 
A
L
 
I
F
 
Y
V
 
F
I
 
V
I
 
M
T
 
T
I
 
L
P
 
T
Q
 
F
A
 
S
R
 
K
F
 
L
V
 
L
D
 
S

Query Sequence

>WP_157520500.1 NCBI__GCF_001653335.1:WP_157520500.1
MGYALAVLLVAGVLGFTTANNGAIATTFLRWEFIADSWEGIAKAFAVNIQVAVGAQVLVL
VVGLALAVMRLLPGRAGRPLRWIATLYVDVFRAIPSIIVLYLVGFGLSLAQVPIVRDFSP
LWLAILALTLTYSAYVAEVYRAGIDSIHPSQWSASRSLGLSYSMTLRTVIVPQAVRRIVP
PLLNDFIGLQKDTALIGVMGVTDAFMQARLVSSNVFNLTPVIVVAVLFVIITIPQARFVD
RLIAGEQARRAGRTS

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory