SitesBLAST
Comparing WP_210399097.1 NCBI__GCF_001579945.1:WP_210399097.1 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4addA Structural and functional study of succinyl-ornithine transaminase from e. Coli (see paper)
38% identity, 95% coverage: 19:399/401 of query aligns to 2:391/400 of 4addA
- active site: F136 (= F148), E188 (= E201), D221 (= D234), Q224 (= Q237), K250 (= K263), T279 (= T292), R372 (= R377)
- binding pyridoxal-5'-phosphate: G103 (= G121), A104 (= A122), F136 (= F148), H137 (= H149), D221 (= D234), V223 (= V236), K250 (= K263)
- binding n~2~-(3-carboxypropanoyl)-l-ornithine: Y16 (= Y32), F136 (= F148), R139 (= R151)
4adbB Structural and functional study of succinyl-ornithine transaminase from e. Coli (see paper)
38% identity, 95% coverage: 19:399/401 of query aligns to 2:391/401 of 4adbB
- active site: F136 (= F148), E188 (= E201), D221 (= D234), Q224 (= Q237), K250 (= K263), T279 (= T292), R372 (= R377)
- binding pyridoxal-5'-phosphate: S102 (= S120), G103 (= G121), A104 (= A122), F136 (= F148), H137 (= H149), D221 (= D234), V223 (= V236), Q224 (= Q237), K250 (= K263)
4jevB N-acetylornithine aminotransferase from s. Typhimurium complexed with gabaculine
41% identity, 74% coverage: 30:326/401 of query aligns to 14:313/402 of 4jevB
- active site: F136 (= F148), E188 (= E201), D221 (= D234), Q224 (= Q237), K250 (= K263), T279 (= T292)
- binding 3-[o-phosphonopyridoxyl]--amino-benzoic acid: I46 (≠ H62), S102 (= S120), G103 (= G121), T104 (≠ A122), F136 (= F148), H137 (= H149), E188 (= E201), E193 (≠ V206), D221 (= D234), V223 (= V236), Q224 (= Q237), K250 (= K263)
Sites not aligning to the query:
P40732 Acetylornithine/succinyldiaminopimelate aminotransferase; ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
41% identity, 74% coverage: 30:326/401 of query aligns to 19:318/405 of P40732
- GT 108:109 (≠ GA 121:122) binding pyridoxal 5'-phosphate
- K255 (= K263) modified: N6-(pyridoxal phosphate)lysine
- T284 (= T292) binding pyridoxal 5'-phosphate
4jewA N-acetylornithine aminotransferase from s. Typhimurium complexed with l-canaline
41% identity, 74% coverage: 30:326/401 of query aligns to 14:308/397 of 4jewA
- active site: F136 (= F148), E188 (= E201), D221 (= D234), Q224 (= Q237), K250 (= K263), T274 (= T292)
- binding (2S)-2-azanyl-4-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]oxy-butanoic acid: G103 (= G121), T104 (≠ A122), F136 (= F148), H137 (= H149), R139 (= R151), E188 (= E201), E193 (≠ V206), D221 (= D234), V223 (= V236), K250 (= K263)
- binding picric acid: K25 (≠ D41), K27 (≠ E43), W32 (≠ H48)
Sites not aligning to the query:
2pb0A Structure of biosynthetic n-acetylornithine aminotransferase from salmonella typhimurium: studies on substrate specificity and inhibitor binding (see paper)
41% identity, 74% coverage: 30:326/401 of query aligns to 8:302/389 of 2pb0A
- active site: F130 (= F148), E182 (= E201), D215 (= D234), Q218 (= Q237), K244 (= K263), T268 (= T292)
- binding pyridoxal-5'-phosphate: S96 (= S120), G97 (= G121), T98 (≠ A122), F130 (= F148), H131 (= H149), E182 (= E201), D215 (= D234), V217 (= V236), Q218 (= Q237), K244 (= K263)
Sites not aligning to the query:
Q9M8M7 Acetylornithine aminotransferase, chloroplastic/mitochondrial; ACOAT; Acetylornithine transaminase; AOTA; Protein HOPW1-1-INTERACTING 1; EC 2.6.1.11 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
35% identity, 90% coverage: 32:391/401 of query aligns to 73:444/457 of Q9M8M7
Sites not aligning to the query:
- 1:41 modified: transit peptide, Chloroplast and mitochondrion
- 42 modified: N-acetylvaline; in Acetylornithine aminotransferase, chloroplastic
O66442 Acetylornithine aminotransferase; ACOAT; EC 2.6.1.11 from Aquifex aeolicus (strain VF5)
34% identity, 93% coverage: 27:399/401 of query aligns to 3:375/376 of O66442
- GT 96:97 (≠ GA 121:122) binding pyridoxal 5'-phosphate
- K242 (= K263) modified: N6-(pyridoxal phosphate)lysine
- T271 (= T292) binding pyridoxal 5'-phosphate
2eh6A Crystal structure of acetylornithine aminotransferase from aquifex aeolicus vf5
34% identity, 93% coverage: 27:399/401 of query aligns to 2:374/375 of 2eh6A
- active site: F127 (= F148), E179 (= E201), D212 (= D234), Q215 (= Q237), K241 (= K263), T270 (= T292), R352 (= R377)
- binding pyridoxal-5'-phosphate: G95 (= G121), T96 (≠ A122), F127 (= F148), H128 (= H149), E179 (= E201), D212 (= D234), V214 (= V236), K241 (= K263)
Q5SHH5 [LysW]-aminoadipate semialdehyde transaminase; EC 2.6.1.118 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
36% identity, 92% coverage: 31:399/401 of query aligns to 23:393/395 of Q5SHH5
- GT 113:114 (≠ GA 121:122) binding pyridoxal 5'-phosphate
- K254 (= K263) modified: N6-(pyridoxal phosphate)lysine
- T283 (= T292) binding pyridoxal 5'-phosphate
1wkhA Acetylornithine aminotransferase from thermus thermophilus hb8
36% identity, 92% coverage: 31:399/401 of query aligns to 15:385/387 of 1wkhA
- active site: F132 (= F148), E184 (= E201), D217 (= D234), Q220 (= Q237), K246 (= K263), T275 (= T292), R363 (= R377)
- binding 4-[(1,3-dicarboxy-propylamino)-methyl]-3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridinium: Y46 (≠ H62), S104 (= S120), G105 (= G121), T106 (≠ A122), F132 (= F148), S133 (≠ H149), E184 (= E201), E189 (≠ V206), D217 (= D234), I219 (≠ V236), K246 (= K263), R363 (= R377)
Sites not aligning to the query:
1wkgA Acetylornithine aminotransferase from thermus thermophilus hb8
36% identity, 92% coverage: 31:399/401 of query aligns to 15:385/387 of 1wkgA
- active site: F132 (= F148), E184 (= E201), D217 (= D234), Q220 (= Q237), K246 (= K263), T275 (= T292), R363 (= R377)
- binding n~2~-acetyl-n~5~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-l-ornithine: Y16 (= Y32), Y46 (≠ H62), G105 (= G121), T106 (≠ A122), F132 (= F148), S133 (≠ H149), R135 (= R151), E184 (= E201), D217 (= D234), I219 (≠ V236), Q220 (= Q237), K246 (= K263), G273 (= G290), T274 (= T291), T275 (= T292)
Sites not aligning to the query:
1vefA Acetylornithine aminotransferase from thermus thermophilus hb8
36% identity, 92% coverage: 31:399/401 of query aligns to 15:385/387 of 1vefA