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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.948 11129142_59_261: single domain, near sugar dehydrogenase, from Aquiflexum balticum BA160, DSM 16537 11227662_34_258: single domain, near sugar dehydrogenase, from Cyclobacterium marinum DSM 745 0.2 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 single domain, near sugar dehydrogenase, from Aquiflexum balticum BA160, DSM 16537 11129142_59_261 single domain, near sugar dehydrogenase, from Aquiflexum balticum BA160, DSM 16537 11129142_59_261 at #155: G1 11129142_59_261 at #155: G1 G 11129142_59_261 at #156: W2 11129142_59_261 at #156: W2 W 11129142_59_261 at #157: M3 11129142_59_261 at #157: M3 M 11129142_59_261 at #158: L4 11129142_59_261 at #158: L4 L 11129142_59_261 at #159: L5 11129142_59_261 at #159: L5 L 11129142_59_261 at #160: F6 11129142_59_261 at #160: F6 F 11129142_59_261 at #162: D7 11129142_59_261 at #162: D7 D 11129142_59_261 at #164: G8 11129142_59_261 at #164: G8 G 11129142_59_261 at #165: V9 11129142_59_261 at #165: V9 V 11129142_59_261 at #168: N10 11129142_59_261 at #168: N10 N 11129142_59_261 at #169: T11 11129142_59_261 at #169: T11 T 11129142_59_261 at #171: D12 11129142_59_261 at #171: D12 D 11129142_59_261 at #172: G13 11129142_59_261 at #172: G13 G 11129142_59_261 at #180: W14 11129142_59_261 at #180: W14 W 11129142_59_261 at #181: R15 11129142_59_261 at #181: R15 R 11129142_59_261 at #185: A16 11129142_59_261 at #185: A16 A 11129142_59_261 at #186: F17 11129142_59_261 at #186: F17 F 11129142_59_261 at #187: N18 11129142_59_261 at #187: N18 N 11129142_59_261 at #188: G19 11129142_59_261 at #188: G19 G 11129142_59_261 at #189: D20 11129142_59_261 at #189: D20 D 11129142_59_261 at #190: T21 11129142_59_261 at #190: T21 T 11129142_59_261 at #191: L22 11129142_59_261 at #191: L22 L 11129142_59_261 at #195: P23 11129142_59_261 at #195: P23 P 11129142_59_261 at #196: P24 11129142_59_261 at #196: P24 P 11129142_59_261 at #197: N25 11129142_59_261 at #197: N25 N 11129142_59_261 at #198: W26 11129142_59_261 at #198: W26 W 11129142_59_261 at #235: T27 11129142_59_261 at #235: T27 T 11129142_59_261 at #236: V28 11129142_59_261 at #236: V28 V 11129142_59_261 at #237: E29 11129142_59_261 at #237: E29 E 11129142_59_261 at #238: D30 11129142_59_261 at #238: D30 D 11129142_59_261 at #240: G31 11129142_59_261 at #240: G31 G 11129142_59_261 at #268: A32 11129142_59_261 at #268: A32 A 11129142_59_261 at #269: L33 11129142_59_261 at #269: L33 L 11129142_59_261 at #270: K34 11129142_59_261 at #270: K34 K 11129142_59_261 at #294: H38 11129142_59_261 at #294: H38 H 11129142_59_261 at #295: D39 11129142_59_261 at #295: D39 D 11129142_59_261 at #296: G40 11129142_59_261 at #296: G40 G 11129142_59_261 at #297: G41 11129142_59_261 at #297: G41 G 11129142_59_261 at #298: D42 11129142_59_261 at #298: D42 D 11129142_59_261 at #299: V43 11129142_59_261 at #299: V43 V 11129142_59_261 at #300: G44 11129142_59_261 at #300: G44 G 11129142_59_261 at #301: G45 11129142_59_261 at #301: G45 G 11129142_59_261 at #303: D46 11129142_59_261 at #303: D46 D 11129142_59_261 at #304: I47 11129142_59_261 at #304: I47 I 11129142_59_261 at #305: V48 11129142_59_261 at #305: V48 V 11129142_59_261 at #306: F49 11129142_59_261 at #306: F49 F 11129142_59_261 at #312: A50 11129142_59_261 at #312: A50 A 11129142_59_261 at #318: P51 11129142_59_261 at #318: P51 P 11129142_59_261 at #321: E53 11129142_59_261 at #321: E53 E 11129142_59_261 at #322: F54 11129142_59_261 at #322: F54 F 11129142_59_261 at #324: E55 11129142_59_261 at #324: E55 E 11129142_59_261 at #326: Q56 11129142_59_261 at #326: Q56 Q 11129142_59_261 at #327: F57 11129142_59_261 at #327: F57 F 11129142_59_261 at #328: E58 11129142_59_261 at #328: E58 E 11129142_59_261 at #329: M59 11129142_59_261 at #329: M59 M 11129142_59_261 at #330: E60 11129142_59_261 at #330: E60 E 11129142_59_261 at #331: F61 11129142_59_261 at #331: F61 F 11129142_59_261 at #332: T62 11129142_59_261 at #332: T62 T 11129142_59_261 at #333: W63 11129142_59_261 at #333: W63 W 11129142_59_261 at #334: K64 11129142_59_261 at #334: K64 K 11129142_59_261 at #335: I65 11129142_59_261 at #335: I65 I 11129142_59_261 at #351: A66 11129142_59_261 at #351: A66 A 11129142_59_261 at #352: T67 11129142_59_261 at #352: T67 T 11129142_59_261 at #354: G68 11129142_59_261 at #354: G68 G 11129142_59_261 at #355: G69 11129142_59_261 at #355: G69 G 11129142_59_261 at #385: N70 11129142_59_261 at #385: N70 N 11129142_59_261 at #386: S71 11129142_59_261 at #386: S71 S 11129142_59_261 at #387: G72 11129142_59_261 at #387: G72 G 11129142_59_261 at #388: V73 11129142_59_261 at #388: V73 V 11129142_59_261 at #389: F74 11129142_59_261 at #389: F74 F 11129142_59_261 at #390: Y75 11129142_59_261 at #390: Y75 Y 11129142_59_261 at #391: H76 11129142_59_261 at #391: H76 H 11129142_59_261 at #392: V77 11129142_59_261 at #392: V77 V 11129142_59_261 at #393: V78 11129142_59_261 at #393: V78 V 11129142_59_261 at #423: P81 11129142_59_261 at #423: P81 P 11129142_59_261 at #424: K82 11129142_59_261 at #424: K82 K 11129142_59_261 at #425: Y83 11129142_59_261 at #425: Y83 Y 11129142_59_261 at #426: A84 11129142_59_261 at #426: A84 A 11129142_59_261 at #430: A85 11129142_59_261 at #430: A85 A 11129142_59_261 at #431: P86 11129142_59_261 at #431: P86 P 11129142_59_261 at #432: Y87 11129142_59_261 at #432: Y87 Y 11129142_59_261 at #433: Y88 11129142_59_261 at #433: Y88 Y 11129142_59_261 at #434: T89 11129142_59_261 at #434: T89 T 11129142_59_261 at #435: G90 11129142_59_261 at #435: G90 G 11129142_59_261 at #436: P91 11129142_59_261 at #436: P91 P 11129142_59_261 at #438: E92 11129142_59_261 at #438: E92 E 11129142_59_261 at #439: Y93 11129142_59_261 at #439: Y93 Y 11129142_59_261 at #440: Q94 11129142_59_261 at #440: Q94 Q 11129142_59_261 at #441: V95 11129142_59_261 at #441: V95 V 11129142_59_261 at #442: I96 11129142_59_261 at #442: I96 I 11129142_59_261 at #443: D97 11129142_59_261 at #443: D97 D 11129142_59_261 at #450: Q98 11129142_59_261 at #450: Q98 Q 11129142_59_261 at #451: L99 11129142_59_261 at #451: L99 L 11129142_59_261 at #452: G100 11129142_59_261 at #452: G100 G 11129142_59_261 at #453: F101 11129142_59_261 at #453: F101 F 11129142_59_261 at #475: L105 11129142_59_261 at #475: L105 L 11129142_59_261 at #476: E106 11129142_59_261 at #476: E106 E 11129142_59_261 at #477: D107 11129142_59_261 at #477: D107 D 11129142_59_261 at #478: W108 11129142_59_261 at #478: W108 W 11129142_59_261 at #479: Q109 11129142_59_261 at #479: Q109 Q 11129142_59_261 at #480: S110 11129142_59_261 at #480: S110 S 11129142_59_261 at #481: L111 11129142_59_261 at #481: L111 L 11129142_59_261 at #482: A112 11129142_59_261 at #482: A112 A 11129142_59_261 at #483: G113 11129142_59_261 at #483: G113 G 11129142_59_261 at #484: D114 11129142_59_261 at #484: D114 D 11129142_59_261 at #485: Y115 11129142_59_261 at #485: Y115 Y 11129142_59_261 at #486: A116 11129142_59_261 at #486: A116 A 11129142_59_261 at #487: M117 11129142_59_261 at #487: M117 M 11129142_59_261 at #530 11129142_59_261 at #530 - 11129142_59_261 at #532 11129142_59_261 at #532 - 11129142_59_261 at #533: Y118 11129142_59_261 at #533: Y118 Y 11129142_59_261 at #534: V119 11129142_59_261 at #534: V119 V 11129142_59_261 at #535: P120 11129142_59_261 at #535: P120 P 11129142_59_261 at #544: D121 11129142_59_261 at #544: D121 D 11129142_59_261 at #545: F122 11129142_59_261 at #545: F122 F 11129142_59_261 at #548: E123 11129142_59_261 at #548: E123 E 11129142_59_261 at #549: G124 11129142_59_261 at #549: G124 G 11129142_59_261 at #550: V125 11129142_59_261 at #550: V125 V 11129142_59_261 at #551: V126 11129142_59_261 at #551: V126 V 11129142_59_261 at #552: K127 11129142_59_261 at #552: K127 K 11129142_59_261 at #553: P128 11129142_59_261 at #553: P128 P 11129142_59_261 at #554: A129 11129142_59_261 at #554: A129 A 11129142_59_261 at #555: G130 11129142_59_261 at #555: G130 G 11129142_59_261 at #556: E131 11129142_59_261 at #556: E131 E 11129142_59_261 at #557: W132 11129142_59_261 at #557: W132 W 11129142_59_261 at #558: N133 11129142_59_261 at #558: N133 N 11129142_59_261 at #559: V134 11129142_59_261 at #559: V134 V 11129142_59_261 at #560: S135 11129142_59_261 at #560: S135 S 11129142_59_261 at #561: K136 11129142_59_261 at #561: K136 K 11129142_59_261 at #562: I137 11129142_59_261 at #562: I137 I 11129142_59_261 at #565: I138 11129142_59_261 at #565: I138 I 11129142_59_261 at #566: F139 11129142_59_261 at #566: F139 F 11129142_59_261 at #568: T140 11129142_59_261 at #568: T140 T 11129142_59_261 at #570: N141 11129142_59_261 at #570: N141 N 11129142_59_261 at #571: E142 11129142_59_261 at #571: E142 E 11129142_59_261 at #572: K143 11129142_59_261 at #572: K143 K 11129142_59_261 at #588: A144 11129142_59_261 at #588: A144 A 11129142_59_261 at #589: E145 11129142_59_261 at #589: E145 E 11129142_59_261 at #592: Y146 11129142_59_261 at #592: Y146 Y 11129142_59_261 at #594: Y147 11129142_59_261 at #594: Y147 Y 11129142_59_261 at #595: L148 11129142_59_261 at #595: L148 L 11129142_59_261 at #596: N149 11129142_59_261 at #596: N149 N 11129142_59_261 at #598: G150 11129142_59_261 at #598: G150 G 11129142_59_261 at #599: K151 11129142_59_261 at #599: K151 K 11129142_59_261 at #600: K152 11129142_59_261 at #600: K152 K 11129142_59_261 at #601: T153 11129142_59_261 at #601: T153 T 11129142_59_261 at #602: V154 11129142_59_261 at #602: V154 V 11129142_59_261 at #603: E155 11129142_59_261 at #603: E155 E 11129142_59_261 at #604: F156 11129142_59_261 at #604: F156 F 11129142_59_261 at #605: V157 11129142_59_261 at #605: V157 V 11129142_59_261 at #606: P158 11129142_59_261 at #606: P158 P 11129142_59_261 at #607: Y159 11129142_59_261 at #607: Y159 Y 11129142_59_261 at #608: S160 11129142_59_261 at #608: S160 S 11129142_59_261 at #609: E161 11129142_59_261 at #609: E161 E 11129142_59_261 at #610: D162 11129142_59_261 at #610: D162 D 11129142_59_261 at #611: W163 11129142_59_261 at #611: W163 W 11129142_59_261 at #612: N164 11129142_59_261 at #612: N164 N 11129142_59_261 at #613: T165 11129142_59_261 at #613: T165 T 11129142_59_261 at #614: K166 11129142_59_261 at #614: K166 K 11129142_59_261 at #615: R167 11129142_59_261 at #615: R167 R 11129142_59_261 at #616: N168 11129142_59_261 at #616: N168 N 11129142_59_261 at #640: A179 11129142_59_261 at #640: A179 A 11129142_59_261 at #641: I180 11129142_59_261 at #641: I180 I 11129142_59_261 at #642: S181 11129142_59_261 at #642: S181 S 11129142_59_261 at #643: K182 11129142_59_261 at #643: K182 K 11129142_59_261 at #644: S183 11129142_59_261 at #644: S183 S 11129142_59_261 at #645: G184 11129142_59_261 at #645: G184 G 11129142_59_261 at #646: L185 11129142_59_261 at #646: L185 L 11129142_59_261 at #647: I186 11129142_59_261 at #647: I186 I 11129142_59_261 at #648: A187 11129142_59_261 at #648: A187 A 11129142_59_261 at #649: L188 11129142_59_261 at #649: L188 L 11129142_59_261 at #650: Q189 11129142_59_261 at #650: Q189 Q 11129142_59_261 at #653: D190 11129142_59_261 at #653: D190 D 11129142_59_261 at #654: H191 11129142_59_261 at #654: H191 H 11129142_59_261 at #655: G192 11129142_59_261 at #655: G192 G 11129142_59_261 at #668: S193 11129142_59_261 at #668: S193 S 11129142_59_261 at #689: E194 11129142_59_261 at #689: E194 E 11129142_59_261 at #690: V195 11129142_59_261 at #690: V195 V 11129142_59_261 at #691: W196 11129142_59_261 at #691: W196 W 11129142_59_261 at #694: F197 11129142_59_261 at #694: F197 F 11129142_59_261 at #695: K198 11129142_59_261 at #695: K198 K 11129142_59_261 at #696: N199 11129142_59_261 at #696: N199 N 11129142_59_261 at #697: I200 11129142_59_261 at #697: I200 I 11129142_59_261 at #698: K201 11129142_59_261 at #698: K201 K 11129142_59_261 at #699: I202 11129142_59_261 at #699: I202 I 11129142_59_261 at #700: R203 11129142_59_261 at #700: R203 R single domain, near sugar dehydrogenase, from Cyclobacterium marinum DSM 745 11227662_34_258 single domain, near sugar dehydrogenase, from Cyclobacterium marinum DSM 745 11227662_34_258 at #155: D1 11227662_34_258 at #155: D1 D 11227662_34_258 at #156: W2 11227662_34_258 at #156: W2 W 11227662_34_258 at #157: I3 11227662_34_258 at #157: I3 I 11227662_34_258 at #158: I4 11227662_34_258 at #158: I4 I 11227662_34_258 at #159: L5 11227662_34_258 at #159: L5 L 11227662_34_258 at #160: F6 11227662_34_258 at #160: F6 F 11227662_34_258 at #162: D7 11227662_34_258 at #162: D7 D 11227662_34_258 at #164: G8 11227662_34_258 at #164: G8 G 11227662_34_258 at #165: T9 11227662_34_258 at #165: T9 T 11227662_34_258 at #168: T10 11227662_34_258 at #168: T10 T 11227662_34_258 at #169: T11 11227662_34_258 at #169: T11 T 11227662_34_258 at #171: E12 11227662_34_258 at #171: E12 E 11227662_34_258 at #172: G13 11227662_34_258 at #172: G13 G 11227662_34_258 at #180: W14 11227662_34_258 at #180: W14 W 11227662_34_258 at #181: R15 11227662_34_258 at #181: R15 R 11227662_34_258 at #185: A16 11227662_34_258 at #185: A16 A 11227662_34_258 at #186: Y17 11227662_34_258 at #186: Y17 Y 11227662_34_258 at #187: N18 11227662_34_258 at #187: N18 N 11227662_34_258 at #188: G19 11227662_34_258 at #188: G19 G 11227662_34_258 at #189: D20 11227662_34_258 at #189: D20 D 11227662_34_258 at #190: E21 11227662_34_258 at #190: E21 E 11227662_34_258 at #191: L22 11227662_34_258 at #191: L22 L 11227662_34_258 at #195: P23 11227662_34_258 at #195: P23 P 11227662_34_258 at #196: P24 11227662_34_258 at #196: P24 P 11227662_34_258 at #197: G25 11227662_34_258 at #197: G25 G 11227662_34_258 at #198: W26 11227662_34_258 at #198: W26 W 11227662_34_258 at #235: I27 11227662_34_258 at #235: I27 I 11227662_34_258 at #236: I28 11227662_34_258 at #236: I28 I 11227662_34_258 at #237: K29 11227662_34_258 at #237: K29 K 11227662_34_258 at #238: N30 11227662_34_258 at #238: N30 N 11227662_34_258 at #240: G31 11227662_34_258 at #240: G31 G 11227662_34_258 at #268: E32 11227662_34_258 at #268: E32 E 11227662_34_258 at #269: L33 11227662_34_258 at #269: L33 L 11227662_34_258 at #270: T34 11227662_34_258 at #270: T34 T 11227662_34_258 at #294: E42 11227662_34_258 at #294: E42 E 11227662_34_258 at #295: Q43 11227662_34_258 at #295: Q43 Q 11227662_34_258 at #296: D44 11227662_34_258 at #296: D44 D 11227662_34_258 at #297: Y45 11227662_34_258 at #297: Y45 Y 11227662_34_258 at #298: T46 11227662_34_258 at #298: T46 T 11227662_34_258 at #299: G47 11227662_34_258 at #299: G47 G 11227662_34_258 at #300: G48 11227662_34_258 at #300: G48 G 11227662_34_258 at #301: K49 11227662_34_258 at #301: K49 K 11227662_34_258 at #303: D50 11227662_34_258 at #303: D50 D 11227662_34_258 at #304: I51 11227662_34_258 at #304: I51 I 11227662_34_258 at #305: I52 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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory