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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.601 11036133_59_263: single domain, from Niastella koreensis GR20-10, DSM 17620 11075721_6_207: single domain, from Pontibacter actiniarum KMM 6156, DSM 19842 0.2 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 single domain, from Niastella koreensis GR20-10, DSM 17620 11036133_59_263 single domain, from Niastella koreensis GR20-10, DSM 17620 11036133_59_263 at #155: G1 11036133_59_263 at #155: G1 G 11036133_59_263 at #156: W2 11036133_59_263 at #156: W2 W 11036133_59_263 at #157: Q3 11036133_59_263 at #157: Q3 Q 11036133_59_263 at #158: L4 11036133_59_263 at #158: L4 L 11036133_59_263 at #159: L5 11036133_59_263 at #159: L5 L 11036133_59_263 at #160: F6 11036133_59_263 at #160: F6 F 11036133_59_263 at #162: D7 11036133_59_263 at #162: D7 D 11036133_59_263 at #164: G8 11036133_59_263 at #164: G8 G 11036133_59_263 at #165: N9 11036133_59_263 at #165: N9 N 11036133_59_263 at #168: S10 11036133_59_263 at #168: S10 S 11036133_59_263 at #169: K11 11036133_59_263 at #169: K11 K 11036133_59_263 at #171: S12 11036133_59_263 at #171: S12 S 11036133_59_263 at #172: N13 11036133_59_263 at #172: N13 N 11036133_59_263 at #180: F14 11036133_59_263 at #180: F14 F 11036133_59_263 at #181: H15 11036133_59_263 at #181: H15 H 11036133_59_263 at #185: V16 11036133_59_263 at #185: V16 V 11036133_59_263 at #186: F17 11036133_59_263 at #186: F17 F 11036133_59_263 at #187: N18 11036133_59_263 at #187: N18 N 11036133_59_263 at #188: K19 11036133_59_263 at #188: K19 K 11036133_59_263 at #189: K20 11036133_59_263 at #189: K20 K 11036133_59_263 at #190: S21 11036133_59_263 at #190: S21 S 11036133_59_263 at #191: D22 11036133_59_263 at #191: D22 D 11036133_59_263 at #195: G23 11036133_59_263 at #195: G23 G 11036133_59_263 at #196: A24 11036133_59_263 at #196: A24 A 11036133_59_263 at #197: A25 11036133_59_263 at #197: A25 A 11036133_59_263 at #198: W26 11036133_59_263 at #198: W26 W 11036133_59_263 at #235: Q27 11036133_59_263 at #235: Q27 Q 11036133_59_263 at #236: I28 11036133_59_263 at #236: I28 I 11036133_59_263 at #237: A29 11036133_59_263 at #237: A29 A 11036133_59_263 at #238: D30 11036133_59_263 at #238: D30 D 11036133_59_263 at #240: G31 11036133_59_263 at #240: G31 G 11036133_59_263 at #268: A32 11036133_59_263 at #268: A32 A 11036133_59_263 at #269: L33 11036133_59_263 at #269: L33 L 11036133_59_263 at #270: H34 11036133_59_263 at #270: H34 H 11036133_59_263 at #294: D42 11036133_59_263 at #294: D42 D 11036133_59_263 at #295: G43 11036133_59_263 at #295: G43 G 11036133_59_263 at #296: K44 11036133_59_263 at #296: K44 K 11036133_59_263 at #297: I45 11036133_59_263 at #297: I45 I 11036133_59_263 at #298: T46 11036133_59_263 at #298: T46 T 11036133_59_263 at #299: G47 11036133_59_263 at #299: G47 G 11036133_59_263 at #300: G48 11036133_59_263 at #300: G48 G 11036133_59_263 at #301: G49 11036133_59_263 at #301: G49 G 11036133_59_263 at #303: D50 11036133_59_263 at #303: D50 D 11036133_59_263 at #304: L51 11036133_59_263 at #304: L51 L 11036133_59_263 at #305: V52 11036133_59_263 at #305: V52 V 11036133_59_263 at #306: T53 11036133_59_263 at #306: T53 T 11036133_59_263 at #312: N54 11036133_59_263 at #312: N54 N 11036133_59_263 at #318: D55 11036133_59_263 at #318: D55 D 11036133_59_263 at #321: E56 11036133_59_263 at #321: E56 E 11036133_59_263 at #322: Y57 11036133_59_263 at #322: Y57 Y 11036133_59_263 at #324: D58 11036133_59_263 at #324: D58 D 11036133_59_263 at #326: N59 11036133_59_263 at #326: N59 N 11036133_59_263 at #327: F60 11036133_59_263 at #327: F60 F 11036133_59_263 at #328: D61 11036133_59_263 at #328: D61 D 11036133_59_263 at #329: L62 11036133_59_263 at #329: L62 L 11036133_59_263 at #330: K63 11036133_59_263 at #330: K63 K 11036133_59_263 at #331: L64 11036133_59_263 at #331: L64 L 11036133_59_263 at #332: E65 11036133_59_263 at #332: E65 E 11036133_59_263 at #333: W66 11036133_59_263 at #333: W66 W 11036133_59_263 at #334: K67 11036133_59_263 at #334: K67 K 11036133_59_263 at #335: I68 11036133_59_263 at #335: I68 I 11036133_59_263 at #351: S69 11036133_59_263 at #351: S69 S 11036133_59_263 at #352: A70 11036133_59_263 at #352: A70 A 11036133_59_263 at #354: G71 11036133_59_263 at #354: G71 G 11036133_59_263 at #355: G72 11036133_59_263 at #355: G72 G 11036133_59_263 at #385: N73 11036133_59_263 at #385: N73 N 11036133_59_263 at #386: S74 11036133_59_263 at #386: S74 S 11036133_59_263 at #387: G75 11036133_59_263 at #387: G75 G 11036133_59_263 at #388: I76 11036133_59_263 at #388: I76 I 11036133_59_263 at #389: L77 11036133_59_263 at #389: L77 L 11036133_59_263 at #390: F78 11036133_59_263 at #390: F78 F 11036133_59_263 at #391: Y79 11036133_59_263 at #391: Y79 Y 11036133_59_263 at #392: V80 11036133_59_263 at #392: V80 V 11036133_59_263 at #393: Q81 11036133_59_263 at #393: Q81 Q 11036133_59_263 at #423: P84 11036133_59_263 at #423: P84 P 11036133_59_263 at #424: K85 11036133_59_263 at #424: K85 K 11036133_59_263 at #425: F86 11036133_59_263 at #425: F86 F 11036133_59_263 at #426: G87 11036133_59_263 at #426: G87 G 11036133_59_263 at #430: E88 11036133_59_263 at #430: E88 E 11036133_59_263 at #431: T89 11036133_59_263 at #431: T89 T 11036133_59_263 at #432: Y90 11036133_59_263 at #432: Y90 Y 11036133_59_263 at #433: H91 11036133_59_263 at #433: H91 H 11036133_59_263 at #434: T92 11036133_59_263 at #434: T92 T 11036133_59_263 at #435: G93 11036133_59_263 at #435: G93 G 11036133_59_263 at #436: P94 11036133_59_263 at #436: P94 P 11036133_59_263 at #438: E95 11036133_59_263 at #438: E95 E 11036133_59_263 at #439: M96 11036133_59_263 at #439: M96 M 11036133_59_263 at #440: Q97 11036133_59_263 at #440: Q97 Q 11036133_59_263 at #441: V98 11036133_59_263 at #441: V98 V 11036133_59_263 at #442: L99 11036133_59_263 at #442: L99 L 11036133_59_263 at #443: D100 11036133_59_263 at #443: D100 D 11036133_59_263 at #450: N101 11036133_59_263 at #450: N101 N 11036133_59_263 at #451: A102 11036133_59_263 at #451: A102 A 11036133_59_263 at #452: A103 11036133_59_263 at #452: A103 A 11036133_59_263 at #453: H104 11036133_59_263 at #453: H104 H 11036133_59_263 at #475: K108 11036133_59_263 at #475: K108 K 11036133_59_263 at #476: I109 11036133_59_263 at #476: I109 I 11036133_59_263 at #477: I110 11036133_59_263 at #477: I110 I 11036133_59_263 at #478: K111 11036133_59_263 at #478: K111 K 11036133_59_263 at #479: H112 11036133_59_263 at #479: H112 H 11036133_59_263 at #480: R113 11036133_59_263 at #480: R113 R 11036133_59_263 at #481: A114 11036133_59_263 at #481: A114 A 11036133_59_263 at #482: G115 11036133_59_263 at #482: G115 G 11036133_59_263 at #483: D116 11036133_59_263 at #483: D116 D 11036133_59_263 at #484: L117 11036133_59_263 at #484: L117 L 11036133_59_263 at #485: Y118 11036133_59_263 at #485: Y118 Y 11036133_59_263 at #486: D119 11036133_59_263 at #486: D119 D 11036133_59_263 at #487 11036133_59_263 at #487 - 11036133_59_263 at #530 11036133_59_263 at #530 - 11036133_59_263 at #532 11036133_59_263 at #532 - 11036133_59_263 at #533: L120 11036133_59_263 at #533: L120 L 11036133_59_263 at #534: I121 11036133_59_263 at #534: I121 I 11036133_59_263 at #535: T122 11036133_59_263 at #535: T122 T 11036133_59_263 at #544: S123 11036133_59_263 at #544: S123 S 11036133_59_263 at #545: T124 11036133_59_263 at #545: T124 T 11036133_59_263 at #548: P125 11036133_59_263 at #548: P125 P 11036133_59_263 at #549: E126 11036133_59_263 at #549: E126 E 11036133_59_263 at #550: T127 11036133_59_263 at #550: T127 T 11036133_59_263 at #551: V128 11036133_59_263 at #551: V128 V 11036133_59_263 at #552: K129 11036133_59_263 at #552: K129 K 11036133_59_263 at #553: P130 11036133_59_263 at #553: P130 P 11036133_59_263 at #554: A131 11036133_59_263 at #554: A131 A 11036133_59_263 at #555: G132 11036133_59_263 at #555: G132 G 11036133_59_263 at #556: E133 11036133_59_263 at #556: E133 E 11036133_59_263 at #557: W134 11036133_59_263 at #557: W134 W 11036133_59_263 at #558: N135 11036133_59_263 at #558: N135 N 11036133_59_263 at #559: Q136 11036133_59_263 at #559: Q136 Q 11036133_59_263 at #560: V137 11036133_59_263 at #560: V137 V 11036133_59_263 at #561: E138 11036133_59_263 at #561: E138 E 11036133_59_263 at #562: I139 11036133_59_263 at #562: I139 I 11036133_59_263 at #565: I140 11036133_59_263 at #565: I140 I 11036133_59_263 at #566: S141 11036133_59_263 at #566: S141 S 11036133_59_263 at #568: N142 11036133_59_263 at #568: N142 N 11036133_59_263 at #570: K143 11036133_59_263 at #570: K143 K 11036133_59_263 at #571: G144 11036133_59_263 at #571: G144 G 11036133_59_263 at #572: A145 11036133_59_263 at #572: A145 A 11036133_59_263 at #588: L146 11036133_59_263 at #588: L146 L 11036133_59_263 at #589: E147 11036133_59_263 at #589: E147 E 11036133_59_263 at #592: F148 11036133_59_263 at #592: F148 F 11036133_59_263 at #594: H149 11036133_59_263 at #594: H149 H 11036133_59_263 at #595: L150 11036133_59_263 at #595: L150 L 11036133_59_263 at #596: N151 11036133_59_263 at #596: N151 N 11036133_59_263 at #598: G152 11036133_59_263 at #598: G152 G 11036133_59_263 at #599: T153 11036133_59_263 at #599: T153 T 11036133_59_263 at #600: K154 11036133_59_263 at #600: K154 K 11036133_59_263 at #601: V155 11036133_59_263 at #601: V155 V 11036133_59_263 at #602: V156 11036133_59_263 at #602: V156 V 11036133_59_263 at #603: S157 11036133_59_263 at #603: S157 S 11036133_59_263 at #604: T158 11036133_59_263 at #604: T158 T 11036133_59_263 at #605: T159 11036133_59_263 at #605: T159 T 11036133_59_263 at #606: L160 11036133_59_263 at #606: L160 L 11036133_59_263 at #607: W161 11036133_59_263 at #607: W161 W 11036133_59_263 at #608: D162 11036133_59_263 at #608: D162 D 11036133_59_263 at #609: D163 11036133_59_263 at #609: D163 D 11036133_59_263 at #610: A164 11036133_59_263 at #610: A164 A 11036133_59_263 at #611: W165 11036133_59_263 at #611: W165 W 11036133_59_263 at #612: K166 11036133_59_263 at #612: K166 K 11036133_59_263 at #613: K167 11036133_59_263 at #613: K167 K 11036133_59_263 at #614: M168 11036133_59_263 at #614: M168 M 11036133_59_263 at #615: V169 11036133_59_263 at #615: V169 V 11036133_59_263 at #616: A170 11036133_59_263 at #616: A170 A 11036133_59_263 at #640: G181 11036133_59_263 at #640: G181 G 11036133_59_263 at #641: T182 11036133_59_263 at #641: T182 T 11036133_59_263 at #642: Y183 11036133_59_263 at #642: Y183 Y 11036133_59_263 at #643: K184 11036133_59_263 at #643: K184 K 11036133_59_263 at #644: T185 11036133_59_263 at #644: T185 T 11036133_59_263 at #645: G186 11036133_59_263 at #645: G186 G 11036133_59_263 at #646: H187 11036133_59_263 at #646: H187 H 11036133_59_263 at #647: I188 11036133_59_263 at #647: I188 I 11036133_59_263 at #648: A189 11036133_59_263 at #648: A189 A 11036133_59_263 at #649: L190 11036133_59_263 at #649: L190 L 11036133_59_263 at #650: Q191 11036133_59_263 at #650: Q191 Q 11036133_59_263 at #653: D192 11036133_59_263 at #653: D192 D 11036133_59_263 at #654: H193 11036133_59_263 at #654: H193 H 11036133_59_263 at #655: G194 11036133_59_263 at #655: G194 G 11036133_59_263 at #668: N195 11036133_59_263 at #668: N195 N 11036133_59_263 at #689: A196 11036133_59_263 at #689: A196 A 11036133_59_263 at #690: V197 11036133_59_263 at #690: V197 V 11036133_59_263 at #691: W198 11036133_59_263 at #691: W198 W 11036133_59_263 at #694: Y199 11036133_59_263 at #694: Y199 Y 11036133_59_263 at #695: R200 11036133_59_263 at #695: R200 R 11036133_59_263 at #696: N201 11036133_59_263 at #696: N201 N 11036133_59_263 at #697: I202 11036133_59_263 at #697: I202 I 11036133_59_263 at #698: R203 11036133_59_263 at #698: R203 R 11036133_59_263 at #699: I204 11036133_59_263 at #699: I204 I 11036133_59_263 at #700: K205 11036133_59_263 at #700: K205 K single domain, from Pontibacter actiniarum KMM 6156, DSM 19842 11075721_6_207 single domain, from Pontibacter actiniarum KMM 6156, DSM 19842 11075721_6_207 at #155 11075721_6_207 at #155 - 11075721_6_207 at #156: W1 11075721_6_207 at #156: W1 W 11075721_6_207 at #157: A2 11075721_6_207 at #157: A2 A 11075721_6_207 at #158: P3 11075721_6_207 at #158: P3 P 11075721_6_207 at #159: L4 11075721_6_207 at #159: L4 L 11075721_6_207 at #160: F5 11075721_6_207 at #160: F5 F 11075721_6_207 at #162: N6 11075721_6_207 at #162: N6 N 11075721_6_207 at #164: G7 11075721_6_207 at #164: G7 G 11075721_6_207 at #165: E8 11075721_6_207 at #165: E8 E 11075721_6_207 at #168: T9 11075721_6_207 at #168: T9 T 11075721_6_207 at #169: T10 11075721_6_207 at #169: T10 T 11075721_6_207 at #171: S11 11075721_6_207 at #171: S11 S 11075721_6_207 at #172: G12 11075721_6_207 at #172: G12 G 11075721_6_207 at #180: W13 11075721_6_207 at #180: W13 W 11075721_6_207 at #181: H14 11075721_6_207 at #181: H14 H 11075721_6_207 at #185: S15 11075721_6_207 at #185: S15 S 11075721_6_207 at #186: Y16 11075721_6_207 at #186: Y16 Y 11075721_6_207 at #187: G17 11075721_6_207 at #187: G17 G 11075721_6_207 at #188: Q18 11075721_6_207 at #188: Q18 Q 11075721_6_207 at #189: P19 11075721_6_207 at #189: P19 P 11075721_6_207 at #190: A20 11075721_6_207 at #190: A20 A 11075721_6_207 at #191: A21 11075721_6_207 at #191: A21 A 11075721_6_207 at #195: G22 11075721_6_207 at #195: G22 G 11075721_6_207 at #196: A23 11075721_6_207 at #196: A23 A 11075721_6_207 at #197: A24 11075721_6_207 at #197: A24 A 11075721_6_207 at #198: W25 11075721_6_207 at #198: W25 W 11075721_6_207 at #235: E26 11075721_6_207 at #235: E26 E 11075721_6_207 at #236: V27 11075721_6_207 at #236: V27 V 11075721_6_207 at #237: R28 11075721_6_207 at #237: R28 R 11075721_6_207 at #238: A29 11075721_6_207 at #238: A29 A 11075721_6_207 at #240: G30 11075721_6_207 at #240: G30 G 11075721_6_207 at #268: A31 11075721_6_207 at #268: A31 A 11075721_6_207 at #269: L32 11075721_6_207 at #269: L32 L 11075721_6_207 at #270: Y33 11075721_6_207 at #270: Y33 Y 11075721_6_207 at #294: K39 11075721_6_207 at #294: K39 K 11075721_6_207 at #295: A40 11075721_6_207 at #295: A40 A 11075721_6_207 at #296: K41 11075721_6_207 at #296: K41 K 11075721_6_207 at #297: G42 11075721_6_207 at #297: G42 G 11075721_6_207 at #298: A43 11075721_6_207 at #298: A43 A 11075721_6_207 at #299: T44 11075721_6_207 at #299: T44 T 11075721_6_207 at #300: G45 11075721_6_207 at #300: G45 G 11075721_6_207 at #301: G46 11075721_6_207 at #301: G46 G 11075721_6_207 at #303: D47 11075721_6_207 at #303: D47 D 11075721_6_207 at #304: L48 11075721_6_207 at #304: L48 L 11075721_6_207 at #305: V49 11075721_6_207 at #305: V49 V 11075721_6_207 at #306: S50 11075721_6_207 at #306: S50 S 11075721_6_207 at #312: A51 11075721_6_207 at #312: A51 A 11075721_6_207 at #318: G52 11075721_6_207 at #318: G52 G 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11075721_6_207 at #698: F201 11075721_6_207 at #698: F201 F 11075721_6_207 at #699: I202 11075721_6_207 at #699: I202 I 11075721_6_207 at #700 11075721_6_207 at #700 - download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory