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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.917 0.899 0.255 0.456 0.223 0.946 6003772_60_269: with redox domain, from Verrucomicrobium spinosum DSM 4136 11228697_40_270: single domain, near sugar dehydrogenase, from Cyclobacterium marinum DSM 745 0.935 0.954 0.194 7665029_26_279: single domain, from Hirschia baltica ATCC 49814 10266833_46_287: single domain, from Spirosoma linguale DSM 74 0.839 5646854_22_277: single domain, from Opitutus terrae PB90-1 0.882 0.165 11023056_44_295: single domain, from Cellulophaga algicola IC166, DSM 14237 0.989 3500619_44_289: single domain, from Pseudoalteromonas atlantica T6c 11202245_37_274: single domain, from Cytophaga fermentans IAM 14302, DSM 9555 0.998 1261712_62_315: single domain, from Novosphingobium aromaticivorans DSM 12444 7044010_37_278: single domain, from Caulobacter sp. K31 5708882_24_263: single domain, from Cellvibrio japonicus Ueda107 0.840 11035244_21_215: single domain, from Niastella koreensis GR20-10, DSM 17620 0.896 10359430_45_269: single domain, from Coraliomargarita akajimensis DSM 45221 4593654_515_746: with redox domain, from Planctomyces maris DSM 8797 11185153_25_218: single domain, from Ornithobacterium rhinotracheale DSM 15997 3395994_38_271: single domain, from Novosphingobium aromaticivorans DSM 12444 1.000 10981894_25_253: single domain, from Leadbetterella byssophila 4M15, DSM 17132 0.882 0.974 5848961_43_276: single domain, from Caulobacter crescentus NA1000 7094637_39_268: single domain, from Sphingomonas wittichii RW1 0.355 11295415_26_253: single domain, from Planctomyces brasiliensis DSM 5305 0.789 7399905_41_280: single domain, from Dyadobacter fermentans DSM 18053 0.049 2712523_30_259: single domain, from Tenacibaculum sp. MED152 2766517_33_261: single domain, from Flavobacteriales bacterium HTCC2170 1 /site with redox domain, from Verrucomicrobium spinosum DSM 4136 6003772_60_269 with redox domain, from Verrucomicrobium spinosum DSM 4136 single domain, near sugar dehydrogenase, from Cyclobacterium marinum DSM 745 11228697_40_270 single domain, near sugar dehydrogenase, from Cyclobacterium marinum DSM 745 single domain, from Hirschia baltica ATCC 49814 7665029_26_279 single domain, from Hirschia baltica ATCC 49814 single domain, from Spirosoma linguale DSM 74 10266833_46_287 single domain, from Spirosoma linguale DSM 74 single domain, from Opitutus terrae PB90-1 5646854_22_277 single domain, from Opitutus terrae PB90-1 single domain, from Cellulophaga algicola IC166, DSM 14237 11023056_44_295 single domain, from Cellulophaga algicola IC166, DSM 14237 single domain, from Pseudoalteromonas atlantica T6c 3500619_44_289 single domain, from Pseudoalteromonas atlantica T6c single domain, from Cytophaga fermentans IAM 14302, DSM 9555 11202245_37_274 single domain, from Cytophaga fermentans IAM 14302, DSM 9555 single domain, from Novosphingobium aromaticivorans DSM 12444 1261712_62_315 single domain, from Novosphingobium aromaticivorans DSM 12444 single domain, from Caulobacter sp. K31 7044010_37_278 single domain, from Caulobacter sp. K31 single domain, from Cellvibrio japonicus Ueda107 5708882_24_263 single domain, from Cellvibrio japonicus Ueda107 single domain, from Niastella koreensis GR20-10, DSM 17620 11035244_21_215 single domain, from Niastella koreensis GR20-10, DSM 17620 single domain, from Coraliomargarita akajimensis DSM 45221 10359430_45_269 single domain, from Coraliomargarita akajimensis DSM 45221 with redox domain, from Planctomyces maris DSM 8797 4593654_515_746 with redox domain, from Planctomyces maris DSM 8797 single domain, from Ornithobacterium rhinotracheale DSM 15997 11185153_25_218 single domain, from Ornithobacterium rhinotracheale DSM 15997 single domain, from Novosphingobium aromaticivorans DSM 12444 3395994_38_271 single domain, from Novosphingobium aromaticivorans DSM 12444 single domain, from Leadbetterella byssophila 4M15, DSM 17132 10981894_25_253 single domain, from Leadbetterella byssophila 4M15, DSM 17132 single domain, from Caulobacter crescentus NA1000 5848961_43_276 single domain, from Caulobacter crescentus NA1000 single domain, from Sphingomonas wittichii RW1 7094637_39_268 single domain, from Sphingomonas wittichii RW1 single domain, from Planctomyces brasiliensis DSM 5305 11295415_26_253 single domain, from Planctomyces brasiliensis DSM 5305 single domain, from Dyadobacter fermentans DSM 18053 7399905_41_280 single domain, from Dyadobacter fermentans DSM 18053 single domain, from Tenacibaculum sp. MED152 2712523_30_259 single domain, from Tenacibaculum sp. MED152 single domain, from Flavobacteriales bacterium HTCC2170 2766517_33_261 single domain, from Flavobacteriales bacterium HTCC2170 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory