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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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Highlight proteins:

0.839 5646854_22_277: single domain, from Opitutus terrae PB90-1 0.882 0.165 11023056_44_295: single domain, from Cellulophaga algicola IC166, DSM 14237 0.989 3500619_44_289: single domain, from Pseudoalteromonas atlantica T6c 11202245_37_274: single domain, from Cytophaga fermentans IAM 14302, DSM 9555 0.998 1261712_62_315: single domain, from Novosphingobium aromaticivorans DSM 12444 7044010_37_278: single domain, from Caulobacter sp. K31 0.5 /site single domain, from Opitutus terrae PB90-1 5646854_22_277 single domain, from Opitutus terrae PB90-1 single domain, from Cellulophaga algicola IC166, DSM 14237 11023056_44_295 single domain, from Cellulophaga algicola IC166, DSM 14237 single domain, from Pseudoalteromonas atlantica T6c 3500619_44_289 single domain, from Pseudoalteromonas atlantica T6c single domain, from Cytophaga fermentans IAM 14302, DSM 9555 11202245_37_274 single domain, from Cytophaga fermentans IAM 14302, DSM 9555 single domain, from Novosphingobium aromaticivorans DSM 12444 1261712_62_315 single domain, from Novosphingobium aromaticivorans DSM 12444 single domain, from Caulobacter sp. K31 7044010_37_278 single domain, from Caulobacter sp. K31 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory