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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.896 10359430_45_269: single domain, from Coraliomargarita akajimensis DSM 45221 4593654_515_746: with redox domain, from Planctomyces maris DSM 8797 0.5 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 single domain, from Coraliomargarita akajimensis DSM 45221 10359430_45_269 single domain, from Coraliomargarita akajimensis DSM 45221 10359430_45_269 at #155 10359430_45_269 at #155 - 10359430_45_269 at #156: Y1 10359430_45_269 at #156: Y1 Y 10359430_45_269 at #157: T2 10359430_45_269 at #157: T2 T 10359430_45_269 at #158: A3 10359430_45_269 at #158: A3 A 10359430_45_269 at #159: L4 10359430_45_269 at #159: L4 L 10359430_45_269 at #160: F5 10359430_45_269 at #160: F5 F 10359430_45_269 at #162: N6 10359430_45_269 at #162: N6 N 10359430_45_269 at #164: G7 10359430_45_269 at #164: G7 G 10359430_45_269 at #165: E8 10359430_45_269 at #165: E8 E 10359430_45_269 at #168: D9 10359430_45_269 at #168: D9 D 10359430_45_269 at #169: L10 10359430_45_269 at #169: L10 L 10359430_45_269 at #171: S11 10359430_45_269 at #171: S11 S 10359430_45_269 at #172: G12 10359430_45_269 at #172: G12 G 10359430_45_269 at #180: W13 10359430_45_269 at #180: W13 W 10359430_45_269 at #181: N14 10359430_45_269 at #181: N14 N 10359430_45_269 at #185: P15 10359430_45_269 at #185: P15 P 10359430_45_269 at #186: V16 10359430_45_269 at #186: V16 V 10359430_45_269 at #187: L17 10359430_45_269 at #187: L17 L 10359430_45_269 at #188: R18 10359430_45_269 at #188: R18 R 10359430_45_269 at #189: V19 10359430_45_269 at #189: V19 V 10359430_45_269 at #190: P20 10359430_45_269 at #190: P20 P 10359430_45_269 at #191: T21 10359430_45_269 at #191: T21 T 10359430_45_269 at #195: P23 10359430_45_269 at #195: P23 P 10359430_45_269 at #196: R24 10359430_45_269 at #196: R24 R 10359430_45_269 at #197: A25 10359430_45_269 at #197: A25 A 10359430_45_269 at #198: D26 10359430_45_269 at #198: D26 D 10359430_45_269 at #235: Q30 10359430_45_269 at #235: Q30 Q 10359430_45_269 at #236: V31 10359430_45_269 at #236: V31 V 10359430_45_269 at #237: E32 10359430_45_269 at #237: E32 E 10359430_45_269 at #238: D33 10359430_45_269 at #238: D33 D 10359430_45_269 at #240: G34 10359430_45_269 at #240: G34 G 10359430_45_269 at #268: A35 10359430_45_269 at #268: A35 A 10359430_45_269 at #269: I36 10359430_45_269 at #269: I36 I 10359430_45_269 at #270: H37 10359430_45_269 at #270: H37 H 10359430_45_269 at #294: E50 10359430_45_269 at #294: E50 E 10359430_45_269 at #295: R51 10359430_45_269 at #295: R51 R 10359430_45_269 at #296: R52 10359430_45_269 at #296: R52 R 10359430_45_269 at #297: N53 10359430_45_269 at #297: N53 N 10359430_45_269 at #298: A54 10359430_45_269 at #298: A54 A 10359430_45_269 at #299: T55 10359430_45_269 at #299: T55 T 10359430_45_269 at #300: H56 10359430_45_269 at #300: H56 H 10359430_45_269 at #301: G57 10359430_45_269 at #301: G57 G 10359430_45_269 at #303: M58 10359430_45_269 at #303: M58 M 10359430_45_269 at #304: L59 10359430_45_269 at #304: L59 L 10359430_45_269 at #305: F60 10359430_45_269 at #305: F60 F 10359430_45_269 at #306: T61 10359430_45_269 at #306: T61 T 10359430_45_269 at #312: E62 10359430_45_269 at #312: E62 E 10359430_45_269 at #318: Q63 10359430_45_269 at #318: Q63 Q 10359430_45_269 at #321: S64 10359430_45_269 at #321: S64 S 10359430_45_269 at #322: F65 10359430_45_269 at #322: F65 F 10359430_45_269 at #324: S66 10359430_45_269 at #324: S66 S 10359430_45_269 at #326: R67 10359430_45_269 at #326: R67 R 10359430_45_269 at #327: F68 10359430_45_269 at #327: F68 F 10359430_45_269 at #328: I69 10359430_45_269 at #328: I69 I 10359430_45_269 at #329: L70 10359430_45_269 at #329: L70 L 10359430_45_269 at #330: R71 10359430_45_269 at #330: R71 R 10359430_45_269 at #331: F72 10359430_45_269 at #331: F72 F 10359430_45_269 at #332: E73 10359430_45_269 at #332: E73 E 10359430_45_269 at #333: Y74 10359430_45_269 at #333: Y74 Y 10359430_45_269 at #334: K75 10359430_45_269 at #334: K75 K 10359430_45_269 at #335: W76 10359430_45_269 at #335: W76 W 10359430_45_269 at #351: N82 10359430_45_269 at #351: N82 N 10359430_45_269 at #352 10359430_45_269 at #352 - 10359430_45_269 at #354 10359430_45_269 at #354 - 10359430_45_269 at #355: N83 10359430_45_269 at #355: N83 N 10359430_45_269 at #385: D90 10359430_45_269 at #385: D90 D 10359430_45_269 at #386: A91 10359430_45_269 at #386: A91 A 10359430_45_269 at #387: G92 10359430_45_269 at #387: G92 G 10359430_45_269 at #388: V93 10359430_45_269 at #388: V93 V 10359430_45_269 at #389: Y94 10359430_45_269 at #389: Y94 Y 10359430_45_269 at #390: Y95 10359430_45_269 at #390: Y95 Y 10359430_45_269 at #391: H96 10359430_45_269 at #391: H96 H 10359430_45_269 at #392: I97 10359430_45_269 at #392: I97 I 10359430_45_269 at #393: S98 10359430_45_269 at #393: S98 S 10359430_45_269 at #423 10359430_45_269 at #423 - 10359430_45_269 at #424 10359430_45_269 at #424 - 10359430_45_269 at #425: G99 10359430_45_269 at #425: G99 G 10359430_45_269 at #426: Q100 10359430_45_269 at #426: Q100 Q 10359430_45_269 at #430: G101 10359430_45_269 at #430: G101 G 10359430_45_269 at #431: V102 10359430_45_269 at #431: V102 V 10359430_45_269 at #432: W103 10359430_45_269 at #432: W103 W 10359430_45_269 at #433: P104 10359430_45_269 at #433: P104 P 10359430_45_269 at #434: H105 10359430_45_269 at #434: H105 H 10359430_45_269 at #435: G106 10359430_45_269 at #435: G106 G 10359430_45_269 at #436: L107 10359430_45_269 at #436: L107 L 10359430_45_269 at #438: E108 10359430_45_269 at #438: E108 E 10359430_45_269 at #439: Y109 10359430_45_269 at #439: Y109 Y 10359430_45_269 at #440: Q110 10359430_45_269 at #440: Q110 Q 10359430_45_269 at #441: V111 10359430_45_269 at #441: V111 V 10359430_45_269 at #442: R112 10359430_45_269 at #442: R112 R 10359430_45_269 at #443: Y113 10359430_45_269 at #443: Y113 Y 10359430_45_269 at #450: D114 10359430_45_269 at #450: D114 D 10359430_45_269 at #451: H115 10359430_45_269 at #451: H115 H 10359430_45_269 at #452: V116 10359430_45_269 at #452: V116 V 10359430_45_269 at #453: E117 10359430_45_269 at #453: E117 E 10359430_45_269 at #475 10359430_45_269 at #475 - 10359430_45_269 at #476 10359430_45_269 at #476 - 10359430_45_269 at #477: D118 10359430_45_269 at #477: D118 D 10359430_45_269 at #478: R119 10359430_45_269 at #478: R119 R 10359430_45_269 at #479: N120 10359430_45_269 at #479: N120 N 10359430_45_269 at #480: H121 10359430_45_269 at #480: H121 H 10359430_45_269 at #481: T122 10359430_45_269 at #481: T122 T 10359430_45_269 at #482: G123 10359430_45_269 at #482: G123 G 10359430_45_269 at #483: D124 10359430_45_269 at #483: D124 D 10359430_45_269 at #484: F125 10359430_45_269 at #484: F125 F 10359430_45_269 at #485: W126 10359430_45_269 at #485: W126 W 10359430_45_269 at #486: A127 10359430_45_269 at #486: A127 A 10359430_45_269 at #487: S128 10359430_45_269 at #487: S128 S 10359430_45_269 at #530: G157 10359430_45_269 at #530: G157 G 10359430_45_269 at #532 10359430_45_269 at #532 - 10359430_45_269 at #533: E158 10359430_45_269 at #533: E158 E 10359430_45_269 at #534: H159 10359430_45_269 at #534: H159 H 10359430_45_269 at #535: R160 10359430_45_269 at #535: R160 R 10359430_45_269 at #544: K163 10359430_45_269 at #544: K163 K 10359430_45_269 at #545: G164 10359430_45_269 at #545: G164 G 10359430_45_269 at #548: A165 10359430_45_269 at #548: A165 A 10359430_45_269 at #549: S166 10359430_45_269 at #549: S166 S 10359430_45_269 at #550: V167 10359430_45_269 at #550: V167 V 10359430_45_269 at #551: H168 10359430_45_269 at #551: H168 H 10359430_45_269 at #552: K169 10359430_45_269 at #552: K169 K 10359430_45_269 at #553: L170 10359430_45_269 at #553: L170 L 10359430_45_269 at #554: D171 10359430_45_269 at #554: D171 D 10359430_45_269 at #555: G172 10359430_45_269 at #555: G172 G 10359430_45_269 at #556: E173 10359430_45_269 at #556: E173 E 10359430_45_269 at #557: W174 10359430_45_269 at #557: W174 W 10359430_45_269 at #558: N175 10359430_45_269 at #558: N175 N 10359430_45_269 at #559: R176 10359430_45_269 at #559: R176 R 10359430_45_269 at #560: C177 10359430_45_269 at #560: C177 C 10359430_45_269 at #561: E178 10359430_45_269 at #561: E178 E 10359430_45_269 at #562: V179 10359430_45_269 at #562: V179 V 10359430_45_269 at #565: I180 10359430_45_269 at #565: I180 I 10359430_45_269 at #566: V181 10359430_45_269 at #566: V181 V 10359430_45_269 at #568: M182 10359430_45_269 at #568: M182 M 10359430_45_269 at #570: G183 10359430_45_269 at #570: G183 G 10359430_45_269 at #571: S184 10359430_45_269 at #571: S184 S 10359430_45_269 at #572: D185 10359430_45_269 at #572: D185 D 10359430_45_269 at #588: Y186 10359430_45_269 at #588: Y186 Y 10359430_45_269 at #589: A187 10359430_45_269 at #589: A187 A 10359430_45_269 at #592: H189 10359430_45_269 at #592: H189 H 10359430_45_269 at #594: K190 10359430_45_269 at #594: K190 K 10359430_45_269 at #595: L191 10359430_45_269 at #595: L191 L 10359430_45_269 at #596: N192 10359430_45_269 at #596: N192 N 10359430_45_269 at #598: G193 10359430_45_269 at #598: G193 G 10359430_45_269 at #599: Q194 10359430_45_269 at #599: Q194 Q 10359430_45_269 at #600: V195 10359430_45_269 at #600: V195 V 10359430_45_269 at #601: V196 10359430_45_269 at #601: V196 V 10359430_45_269 at #602: N197 10359430_45_269 at #602: N197 N 10359430_45_269 at #603: V198 10359430_45_269 at #603: V198 V 10359430_45_269 at #604: G199 10359430_45_269 at #604: G199 G 10359430_45_269 at #605: T200 10359430_45_269 at #605: T200 T 10359430_45_269 at #606: N201 10359430_45_269 at #606: N201 N 10359430_45_269 at #607: L202 10359430_45_269 at #607: L202 L 10359430_45_269 at #608: T203 10359430_45_269 at #608: T203 T 10359430_45_269 at #609: A204 10359430_45_269 at #609: A204 A 10359430_45_269 at #610 10359430_45_269 at #610 - 10359430_45_269 at #611 10359430_45_269 at #611 - 10359430_45_269 at #612 10359430_45_269 at #612 - 10359430_45_269 at #613 10359430_45_269 at #613 - 10359430_45_269 at #614 10359430_45_269 at #614 - 10359430_45_269 at #615 10359430_45_269 at #615 - 10359430_45_269 at #616 10359430_45_269 at #616 - 10359430_45_269 at #640 10359430_45_269 at #640 - 10359430_45_269 at #641 10359430_45_269 at #641 - 10359430_45_269 at #642 10359430_45_269 at #642 - 10359430_45_269 at #643: G205 10359430_45_269 at #643: G205 G 10359430_45_269 at #644: E206 10359430_45_269 at #644: E206 E 10359430_45_269 at #645: G207 10359430_45_269 at #645: G207 G 10359430_45_269 at #646: V208 10359430_45_269 at #646: V208 V 10359430_45_269 at #647: I209 10359430_45_269 at #647: I209 I 10359430_45_269 at #648: G210 10359430_45_269 at #648: G210 G 10359430_45_269 at #649: L211 10359430_45_269 at #649: L211 L 10359430_45_269 at #650: Q212 10359430_45_269 at #650: Q212 Q 10359430_45_269 at #653: A213 10359430_45_269 at #653: A213 A 10359430_45_269 at #654: E214 10359430_45_269 at #654: E214 E 10359430_45_269 at #655: T215 10359430_45_269 at #655: T215 T 10359430_45_269 at #668: A216 10359430_45_269 at #668: A216 A 10359430_45_269 at #689: E217 10359430_45_269 at #689: E217 E 10359430_45_269 at #690: I218 10359430_45_269 at #690: I218 I 10359430_45_269 at #691: F219 10359430_45_269 at #691: F219 F 10359430_45_269 at #694: Y220 10359430_45_269 at #694: Y220 Y 10359430_45_269 at #695: R221 10359430_45_269 at #695: R221 R 10359430_45_269 at #696: N222 10359430_45_269 at #696: N222 N 10359430_45_269 at #697: I223 10359430_45_269 at #697: I223 I 10359430_45_269 at #698: E224 10359430_45_269 at #698: E224 E 10359430_45_269 at #699: I225 10359430_45_269 at #699: I225 I 10359430_45_269 at #700 10359430_45_269 at #700 - with redox domain, from Planctomyces maris DSM 8797 4593654_515_746 with redox domain, from Planctomyces maris DSM 8797 4593654_515_746 at #155: G1 4593654_515_746 at #155: G1 G 4593654_515_746 at #156: W2 4593654_515_746 at #156: W2 W 4593654_515_746 at #157: R3 4593654_515_746 at #157: R3 R 4593654_515_746 at #158: P4 4593654_515_746 at #158: P4 P 4593654_515_746 at #159: L5 4593654_515_746 at #159: L5 L 4593654_515_746 at #160: F6 4593654_515_746 at #160: F6 F 4593654_515_746 at #162: N7 4593654_515_746 at #162: N7 N 4593654_515_746 at #164: G8 4593654_515_746 at #164: G8 G 4593654_515_746 at #165: N9 4593654_515_746 at #165: N9 N 4593654_515_746 at #168: N10 4593654_515_746 at #168: N10 N 4593654_515_746 at #169: L11 4593654_515_746 at #169: L11 L 4593654_515_746 at #171: D12 4593654_515_746 at #171: D12 D 4593654_515_746 at #172: D13 4593654_515_746 at #172: D13 D 4593654_515_746 at #180: V14 4593654_515_746 at #180: V14 V 4593654_515_746 at #181: D15 4593654_515_746 at #181: D15 D 4593654_515_746 at #185: T16 4593654_515_746 at #185: T16 T 4593654_515_746 at #186: I17 4593654_515_746 at #186: I17 I 4593654_515_746 at #187: L18 4593654_515_746 at #187: L18 L 4593654_515_746 at #188: A19 4593654_515_746 at #188: A19 A 4593654_515_746 at #189: T20 4593654_515_746 at #189: T20 T 4593654_515_746 at #190: K21 4593654_515_746 at #190: K21 K 4593654_515_746 at #191: T22 4593654_515_746 at #191: T22 T 4593654_515_746 at #195: P23 4593654_515_746 at #195: P23 P 4593654_515_746 at #196: I24 4593654_515_746 at #196: I24 I 4593654_515_746 at #197: K25 4593654_515_746 at #197: K25 K 4593654_515_746 at #198: D26 4593654_515_746 at #198: D26 D 4593654_515_746 at #235: Q32 4593654_515_746 at #235: Q32 Q 4593654_515_746 at #236: V33 4593654_515_746 at #236: V33 V 4593654_515_746 at #237: K34 4593654_515_746 at #237: K34 K 4593654_515_746 at #238: D35 4593654_515_746 at #238: D35 D 4593654_515_746 at #240: G36 4593654_515_746 at #240: G36 G 4593654_515_746 at #268: V37 4593654_515_746 at #268: V37 V 4593654_515_746 at #269: F38 4593654_515_746 at #269: F38 F 4593654_515_746 at #270: H39 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4593654_515_746 at #694: Y226 4593654_515_746 at #694: Y226 Y 4593654_515_746 at #695: R227 4593654_515_746 at #695: R227 R 4593654_515_746 at #696: N228 4593654_515_746 at #696: N228 N 4593654_515_746 at #697: I229 4593654_515_746 at #697: I229 I 4593654_515_746 at #698: E230 4593654_515_746 at #698: E230 E 4593654_515_746 at #699: I231 4593654_515_746 at #699: I231 I 4593654_515_746 at #700: K232 4593654_515_746 at #700: K232 K download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory