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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.974 5848961_43_276: single domain, from Caulobacter crescentus NA1000 7094637_39_268: single domain, from Sphingomonas wittichii RW1 0.2 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 single domain, from Caulobacter crescentus NA1000 5848961_43_276 single domain, from Caulobacter crescentus NA1000 5848961_43_276 at #155 5848961_43_276 at #155 - 5848961_43_276 at #156: W1 5848961_43_276 at #156: W1 W 5848961_43_276 at #157: R2 5848961_43_276 at #157: R2 R 5848961_43_276 at #158: S3 5848961_43_276 at #158: S3 S 5848961_43_276 at #159: L4 5848961_43_276 at #159: L4 L 5848961_43_276 at #160: F5 5848961_43_276 at #160: F5 F 5848961_43_276 at #162: D6 5848961_43_276 at #162: D6 D 5848961_43_276 at #164: G7 5848961_43_276 at #164: G7 G 5848961_43_276 at #165: K8 5848961_43_276 at #165: K8 K 5848961_43_276 at #168: T9 5848961_43_276 at #168: T9 T 5848961_43_276 at #169: L10 5848961_43_276 at #169: L10 L 5848961_43_276 at #171: N11 5848961_43_276 at #171: N11 N 5848961_43_276 at #172: G12 5848961_43_276 at #172: G12 G 5848961_43_276 at #180: W13 5848961_43_276 at #180: W13 W 5848961_43_276 at #181: T14 5848961_43_276 at #181: T14 T 5848961_43_276 at #185: A15 5848961_43_276 at #185: A15 A 5848961_43_276 at #186: K16 5848961_43_276 at #186: K16 K 5848961_43_276 at #187: V17 5848961_43_276 at #187: V17 V 5848961_43_276 at #188: A18 5848961_43_276 at #188: A18 A 5848961_43_276 at #189: R19 5848961_43_276 at #189: R19 R 5848961_43_276 at #190: H20 5848961_43_276 at #190: H20 H 5848961_43_276 at #191: P21 5848961_43_276 at #191: P21 P 5848961_43_276 at #195: V22 5848961_43_276 at #195: V22 V 5848961_43_276 at #196: G23 5848961_43_276 at #196: G23 G 5848961_43_276 at #197: E24 5848961_43_276 at #197: E24 E 5848961_43_276 at #198: N25 5848961_43_276 at #198: N25 N 5848961_43_276 at #235: V31 5848961_43_276 at #235: V31 V 5848961_43_276 at #236: A32 5848961_43_276 at #236: A32 A 5848961_43_276 at #237: D33 5848961_43_276 at #237: D33 D 5848961_43_276 at #238: Q34 5848961_43_276 at #238: Q34 Q 5848961_43_276 at #240: G35 5848961_43_276 at #240: G35 G 5848961_43_276 at #268: V36 5848961_43_276 at #268: V36 V 5848961_43_276 at #269: I37 5848961_43_276 at #269: I37 I 5848961_43_276 at #270: R38 5848961_43_276 at #270: R38 R 5848961_43_276 at #294: D45 5848961_43_276 at #294: D45 D 5848961_43_276 at #295: R46 5848961_43_276 at #295: R46 R 5848961_43_276 at #296: F47 5848961_43_276 at #296: F47 F 5848961_43_276 at #297: D48 5848961_43_276 at #297: D48 D 5848961_43_276 at #298: N49 5848961_43_276 at #298: N49 N 5848961_43_276 at #299: Q50 5848961_43_276 at #299: Q50 Q 5848961_43_276 at #300: F51 5848961_43_276 at #300: F51 F 5848961_43_276 at #301: G52 5848961_43_276 at #301: G52 G 5848961_43_276 at #303: H53 5848961_43_276 at #303: H53 H 5848961_43_276 at #304: L54 5848961_43_276 at #304: L54 L 5848961_43_276 at #305: F55 5848961_43_276 at #305: F55 F 5848961_43_276 at #306: H56 5848961_43_276 at #306: H56 H 5848961_43_276 at #312: K57 5848961_43_276 at #312: K57 K 5848961_43_276 at #318: T58 5848961_43_276 at #318: T58 T 5848961_43_276 at #321: P59 5848961_43_276 at #321: P59 P 5848961_43_276 at #322: F60 5848961_43_276 at #322: F60 F 5848961_43_276 at #324: S61 5848961_43_276 at #324: S61 S 5848961_43_276 at #326: A62 5848961_43_276 at #326: A62 A 5848961_43_276 at #327: Y63 5848961_43_276 at #327: Y63 Y 5848961_43_276 at #328: R64 5848961_43_276 at #328: R64 R 5848961_43_276 at #329: L65 5848961_43_276 at #329: L65 L 5848961_43_276 at #330: R66 5848961_43_276 at #330: R66 R 5848961_43_276 at #331: F67 5848961_43_276 at #331: F67 F 5848961_43_276 at #332: S68 5848961_43_276 at #332: S68 S 5848961_43_276 at #333: Y69 5848961_43_276 at #333: Y69 Y 5848961_43_276 at #334: R70 5848961_43_276 at #334: R70 R 5848961_43_276 at #335: F71 5848961_43_276 at #335: F71 F 5848961_43_276 at #351: T73 5848961_43_276 at #351: T73 T 5848961_43_276 at #352: E74 5848961_43_276 at #352: E74 E 5848961_43_276 at #354: G75 5848961_43_276 at #354: G75 G 5848961_43_276 at #355: G76 5848961_43_276 at #355: G76 G 5848961_43_276 at #385: N87 5848961_43_276 at #385: N87 N 5848961_43_276 at #386: S88 5848961_43_276 at #386: S88 S 5848961_43_276 at #387: G89 5848961_43_276 at #387: G89 G 5848961_43_276 at #388: I90 5848961_43_276 at #388: I90 I 5848961_43_276 at #389: M91 5848961_43_276 at #389: M91 M 5848961_43_276 at #390: F92 5848961_43_276 at #390: F92 F 5848961_43_276 at #391: H93 5848961_43_276 at #391: H93 H 5848961_43_276 at #392: S94 5848961_43_276 at #392: S94 S 5848961_43_276 at #393: Q95 5848961_43_276 at #393: Q95 Q 5848961_43_276 at #423: M100 5848961_43_276 at #423: M100 M 5848961_43_276 at #424: T101 5848961_43_276 at #424: T101 T 5848961_43_276 at #425: V102 5848961_43_276 at #425: V102 V 5848961_43_276 at #426: D103 5848961_43_276 at #426: D103 D 5848961_43_276 at #430: Q104 5848961_43_276 at #430: Q104 Q 5848961_43_276 at #431: P105 5848961_43_276 at #431: P105 P 5848961_43_276 at #432: F106 5848961_43_276 at #432: F106 F 5848961_43_276 at #433: P107 5848961_43_276 at #433: P107 P 5848961_43_276 at #434: V108 5848961_43_276 at #434: V108 V 5848961_43_276 at #435: S109 5848961_43_276 at #435: S109 S 5848961_43_276 at #436: I110 5848961_43_276 at #436: I110 I 5848961_43_276 at #438: E111 5848961_43_276 at #438: E111 E 5848961_43_276 at #439: F112 5848961_43_276 at #439: F112 F 5848961_43_276 at #440: Q113 5848961_43_276 at #440: Q113 Q 5848961_43_276 at #441: L114 5848961_43_276 at #441: L114 L 5848961_43_276 at #442: L115 5848961_43_276 at #442: L115 L 5848961_43_276 at #443: G116 5848961_43_276 at #443: G116 G 5848961_43_276 at #450: K117 5848961_43_276 at #450: K117 K 5848961_43_276 at #451: D118 5848961_43_276 at #451: D118 D 5848961_43_276 at #452: G119 5848961_43_276 at #452: G119 G 5848961_43_276 at #453: D120 5848961_43_276 at #453: D120 D 5848961_43_276 at #475 5848961_43_276 at #475 - 5848961_43_276 at #476 5848961_43_276 at #476 - 5848961_43_276 at #477: K121 5848961_43_276 at #477: K121 K 5848961_43_276 at #478: P122 5848961_43_276 at #478: P122 P 5848961_43_276 at #479: R123 5848961_43_276 at #479: R123 R 5848961_43_276 at #480: P124 5848961_43_276 at #480: P124 P 5848961_43_276 at #481: T125 5848961_43_276 at #481: T125 T 5848961_43_276 at #482: G126 5848961_43_276 at #482: G126 G 5848961_43_276 at #483: A127 5848961_43_276 at #483: A127 A 5848961_43_276 at #484: V128 5848961_43_276 at #484: V128 V 5848961_43_276 at #485: C129 5848961_43_276 at #485: C129 C 5848961_43_276 at #486: T130 5848961_43_276 at #486: T130 T 5848961_43_276 at #487: P131 5848961_43_276 at #487: P131 P 5848961_43_276 at #530: K143 5848961_43_276 at #530: K143 K 5848961_43_276 at #532: H145 5848961_43_276 at #532: H145 H 5848961_43_276 at #533: C146 5848961_43_276 at #533: C146 C 5848961_43_276 at #534: T147 5848961_43_276 at #534: T147 T 5848961_43_276 at #535: P148 5848961_43_276 at #535: P148 P 5848961_43_276 at #544: P149 5848961_43_276 at #544: P149 P 5848961_43_276 at #545: A150 5848961_43_276 at #545: A150 A 5848961_43_276 at #548: N151 5848961_43_276 at #548: N151 N 5848961_43_276 at #549: G152 5848961_43_276 at #549: G152 G 5848961_43_276 at #550: P153 5848961_43_276 at #550: P153 P 5848961_43_276 at #551: T154 5848961_43_276 at #551: T154 T 5848961_43_276 at #552: I155 5848961_43_276 at #552: I155 I 5848961_43_276 at #553: A156 5848961_43_276 at #553: A156 A 5848961_43_276 at #554: N157 5848961_43_276 at #554: N157 N 5848961_43_276 at #555: G158 5848961_43_276 at #555: G158 G 5848961_43_276 at #556: T159 5848961_43_276 at #556: T159 T 5848961_43_276 at #557: W160 5848961_43_276 at #557: W160 W 5848961_43_276 at #558: V161 5848961_43_276 at #558: V161 V 5848961_43_276 at #559: Q162 5848961_43_276 at #559: Q162 Q 5848961_43_276 at #560: A163 5848961_43_276 at #560: A163 A 5848961_43_276 at #561: E164 5848961_43_276 at #561: E164 E 5848961_43_276 at #562: L165 5848961_43_276 at #562: L165 L 5848961_43_276 at #565: E166 5848961_43_276 at #565: E166 E 5848961_43_276 at #566: V167 5848961_43_276 at #566: V167 V 5848961_43_276 at #568: L168 5848961_43_276 at #568: L168 L 5848961_43_276 at #570: P169 5848961_43_276 at #570: P169 P 5848961_43_276 at #571: S170 5848961_43_276 at #571: S170 S 5848961_43_276 at #572: G171 5848961_43_276 at #572: G171 G 5848961_43_276 at #588: I173 5848961_43_276 at #588: I173 I 5848961_43_276 at #589: T174 5848961_43_276 at #589: T174 T 5848961_43_276 at #592: Q175 5848961_43_276 at #592: Q175 Q 5848961_43_276 at #594: K176 5848961_43_276 at #594: K176 K 5848961_43_276 at #595: I177 5848961_43_276 at #595: I177 I 5848961_43_276 at #596: N178 5848961_43_276 at #596: N178 N 5848961_43_276 at #598: G179 5848961_43_276 at #598: G179 G 5848961_43_276 at #599: V180 5848961_43_276 at #599: V180 V 5848961_43_276 at #600: V181 5848961_43_276 at #600: V181 V 5848961_43_276 at #601: V182 5848961_43_276 at #601: V182 V 5848961_43_276 at #602: H183 5848961_43_276 at #602: H183 H 5848961_43_276 at #603: R184 5848961_43_276 at #603: R184 R 5848961_43_276 at #604: Y185 5848961_43_276 at #604: Y185 Y 5848961_43_276 at #605: A186 5848961_43_276 at #605: A186 A 5848961_43_276 at #606: G187 5848961_43_276 at #606: G187 G 5848961_43_276 at #607: A188 5848961_43_276 at #607: A188 A 5848961_43_276 at #608: A189 5848961_43_276 at #608: A189 A 5848961_43_276 at #609: L190 5848961_43_276 at #609: L190 L 5848961_43_276 at #610: D191 5848961_43_276 at #610: D191 D 5848961_43_276 at #611: P192 5848961_43_276 at #611: P192 P 5848961_43_276 at #612: D193 5848961_43_276 at #612: D193 D 5848961_43_276 at #613: D194 5848961_43_276 at #613: D194 D 5848961_43_276 at #614: T195 5848961_43_276 at #614: T195 T 5848961_43_276 at #615: V196 5848961_43_276 at #615: V196 V 5848961_43_276 at #616: A197 5848961_43_276 at #616: A197 A 5848961_43_276 at #640: Q210 5848961_43_276 at #640: Q210 Q 5848961_43_276 at #641: P211 5848961_43_276 at #641: P211 P 5848961_43_276 at #642: V212 5848961_43_276 at #642: V212 V 5848961_43_276 at #643: T213 5848961_43_276 at #643: T213 T 5848961_43_276 at #644: G214 5848961_43_276 at #644: G214 G 5848961_43_276 at #645: G215 5848961_43_276 at #645: G215 G 5848961_43_276 at #646: Y216 5848961_43_276 at #646: Y216 Y 5848961_43_276 at #647: I217 5848961_43_276 at #647: I217 I 5848961_43_276 at #648: A218 5848961_43_276 at #648: A218 A 5848961_43_276 at #649: L219 5848961_43_276 at #649: L219 L 5848961_43_276 at #650: Q220 5848961_43_276 at #650: Q220 Q 5848961_43_276 at #653: S221 5848961_43_276 at #653: S221 S 5848961_43_276 at #654: E222 5848961_43_276 at #654: E222 E 5848961_43_276 at #655: G223 5848961_43_276 at #655: G223 G 5848961_43_276 at #668: A224 5848961_43_276 at #668: A224 A 5848961_43_276 at #689: P225 5848961_43_276 at #689: P225 P 5848961_43_276 at #690: L226 5848961_43_276 at #690: L226 L 5848961_43_276 at #691: E227 5848961_43_276 at #691: E227 E 5848961_43_276 at #694: F228 5848961_43_276 at #694: F228 F 5848961_43_276 at #695: K229 5848961_43_276 at #695: K229 K 5848961_43_276 at #696: D230 5848961_43_276 at #696: D230 D 5848961_43_276 at #697: I231 5848961_43_276 at #697: I231 I 5848961_43_276 at #698: E232 5848961_43_276 at #698: E232 E 5848961_43_276 at #699: I233 5848961_43_276 at #699: I233 I 5848961_43_276 at #700: Q234 5848961_43_276 at #700: Q234 Q single domain, from Sphingomonas wittichii RW1 7094637_39_268 single domain, from Sphingomonas wittichii RW1 7094637_39_268 at #155 7094637_39_268 at #155 - 7094637_39_268 at #156: W1 7094637_39_268 at #156: W1 W 7094637_39_268 at #157: R2 7094637_39_268 at #157: R2 R 7094637_39_268 at #158: P3 7094637_39_268 at #158: P3 P 7094637_39_268 at #159: L4 7094637_39_268 at #159: L4 L 7094637_39_268 at #160: F5 7094637_39_268 at #160: F5 F 7094637_39_268 at #162: N6 7094637_39_268 at #162: N6 N 7094637_39_268 at #164: G7 7094637_39_268 at #164: G7 G 7094637_39_268 at #165: H8 7094637_39_268 at #165: H8 H 7094637_39_268 at #168: D9 7094637_39_268 at #168: D9 D 7094637_39_268 at #169: L10 7094637_39_268 at #169: L10 L 7094637_39_268 at #171: D11 7094637_39_268 at #171: D11 D 7094637_39_268 at #172: G12 7094637_39_268 at #172: G12 G 7094637_39_268 at #180: W13 7094637_39_268 at #180: W13 W 7094637_39_268 at #181: V14 7094637_39_268 at #181: V14 V 7094637_39_268 at #185: A15 7094637_39_268 at #185: A15 A 7094637_39_268 at #186: K16 7094637_39_268 at #186: K16 K 7094637_39_268 at #187: I17 7094637_39_268 at #187: I17 I 7094637_39_268 at #188: N18 7094637_39_268 at #188: N18 N 7094637_39_268 at #189: H19 7094637_39_268 at #189: H19 H 7094637_39_268 at #190: H20 7094637_39_268 at #190: H20 H 7094637_39_268 at #191: P21 7094637_39_268 at #191: P21 P 7094637_39_268 at #195: L22 7094637_39_268 at #195: L22 L 7094637_39_268 at #196: G23 7094637_39_268 at #196: G23 G 7094637_39_268 at #197: D24 7094637_39_268 at #197: D24 D 7094637_39_268 at #198: N25 7094637_39_268 at #198: N25 N 7094637_39_268 at #235: V31 7094637_39_268 at #235: V31 V 7094637_39_268 at #236: A32 7094637_39_268 at #236: A32 A 7094637_39_268 at #237: E33 7094637_39_268 at #237: E33 E 7094637_39_268 at #238: G34 7094637_39_268 at #238: G34 G 7094637_39_268 at #240: G35 7094637_39_268 at #240: G35 G 7094637_39_268 at #268: I36 7094637_39_268 at #268: I36 I 7094637_39_268 at #269: L37 7094637_39_268 at #269: L37 L 7094637_39_268 at #270: H38 7094637_39_268 at #270: H38 H 7094637_39_268 at #294: R45 7094637_39_268 at #294: R45 R 7094637_39_268 at #295: G46 7094637_39_268 at #295: G46 G 7094637_39_268 at #296: F47 7094637_39_268 at #296: F47 F 7094637_39_268 at #297: F48 7094637_39_268 at #297: F48 F 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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory