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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.512 11268944_31_219: single domain, from Isosphaera pallida IS1B, ATCC 43644 4911804_24_214: single domain, from Gemmata obscuriglobus UQM 2246 0.2 /site single domain, from Isosphaera pallida IS1B, ATCC 43644 11268944_31_219 single domain, from Isosphaera pallida IS1B, ATCC 43644 single domain, from Gemmata obscuriglobus UQM 2246 4911804_24_214 single domain, from Gemmata obscuriglobus UQM 2246 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory