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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.791 0.891 0.549 0.053 0.880 0.347 7376920_669_882: with redox domain, from Methylobacterium nodulans ORS 2060 5653674_1059_1234: with redox domain, from Streptomyces griseus subsp. griseus NBRC 13350 0.924 0.981 1125827_671_892: with redox domain, from Nitrosospira multiformis ATCC 25196 1126194_16_255: single domain, from Nitrosospira multiformis ATCC 25196 0.994 7409619_978_1192: with redox domain, from Saccharomonospora viridis DSM 43017 0.949 246875_521_727: with other domain, from Streptomyces coelicolor A3(2) 3653714_122_335: single domain, from Saccharopolyspora erythraea NRRL 2338 0.903 5593361_25_197: single domain, from Rhodospirillum centenum SW 0.996 3772626_642_829: with redox domain, from Microcystis aeruginosa NIES-843 4904579_682_860: with redox domain, from Gemmata obscuriglobus UQM 2246 6252404_31_203: single domain, from Chthoniobacter flavus Ellin428 1.000 2225943_20_213: single domain, from Solibacter usitatus Ellin6076 11176218_20_201: single domain, from Gillisia limnaea R-8282, DSM 15749 0.700 0.973 4594548_352_539: with other domain, near sugar dehydrogenase, from Planctomyces maris DSM 8797 0.793 4614230_39_205: single domain, from Lentisphaera araneosa HTCC2155 6253107_21_166: single domain, from Chthoniobacter flavus Ellin428 0.899 11294916_26_207: single domain, from Planctomyces brasiliensis DSM 5305 2224519_22_203: single domain, from Solibacter usitatus Ellin6076 1 /site with redox domain, from Methylobacterium nodulans ORS 2060 7376920_669_882 with redox domain, from Methylobacterium nodulans ORS 2060 with redox domain, from Streptomyces griseus subsp. griseus NBRC 13350 5653674_1059_1234 with redox domain, from Streptomyces griseus subsp. griseus NBRC 13350 with redox domain, from Nitrosospira multiformis ATCC 25196 1125827_671_892 with redox domain, from Nitrosospira multiformis ATCC 25196 single domain, from Nitrosospira multiformis ATCC 25196 1126194_16_255 single domain, from Nitrosospira multiformis ATCC 25196 with redox domain, from Saccharomonospora viridis DSM 43017 7409619_978_1192 with redox domain, from Saccharomonospora viridis DSM 43017 with other domain, from Streptomyces coelicolor A3(2) 246875_521_727 with other domain, from Streptomyces coelicolor A3(2) single domain, from Saccharopolyspora erythraea NRRL 2338 3653714_122_335 single domain, from Saccharopolyspora erythraea NRRL 2338 single domain, from Rhodospirillum centenum SW 5593361_25_197 single domain, from Rhodospirillum centenum SW with redox domain, from Microcystis aeruginosa NIES-843 3772626_642_829 with redox domain, from Microcystis aeruginosa NIES-843 with redox domain, from Gemmata obscuriglobus UQM 2246 4904579_682_860 with redox domain, from Gemmata obscuriglobus UQM 2246 single domain, from Chthoniobacter flavus Ellin428 6252404_31_203 single domain, from Chthoniobacter flavus Ellin428 single domain, from Solibacter usitatus Ellin6076 2225943_20_213 single domain, from Solibacter usitatus Ellin6076 single domain, from Gillisia limnaea R-8282, DSM 15749 11176218_20_201 single domain, from Gillisia limnaea R-8282, DSM 15749 with other domain, near sugar dehydrogenase, from Planctomyces maris DSM 8797 4594548_352_539 with other domain, near sugar dehydrogenase, from Planctomyces maris DSM 8797 single domain, from Lentisphaera araneosa HTCC2155 4614230_39_205 single domain, from Lentisphaera araneosa HTCC2155 single domain, from Chthoniobacter flavus Ellin428 6253107_21_166 single domain, from Chthoniobacter flavus Ellin428 single domain, from Planctomyces brasiliensis DSM 5305 11294916_26_207 single domain, from Planctomyces brasiliensis DSM 5305 single domain, from Solibacter usitatus Ellin6076 2224519_22_203 single domain, from Solibacter usitatus Ellin6076 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory