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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.994 7409619_978_1192: with redox domain, from Saccharomonospora viridis DSM 43017 0.949 246875_521_727: with other domain, from Streptomyces coelicolor A3(2) 3653714_122_335: single domain, from Saccharopolyspora erythraea NRRL 2338 0.5 /site with redox domain, from Saccharomonospora viridis DSM 43017 7409619_978_1192 with redox domain, from Saccharomonospora viridis DSM 43017 with other domain, from Streptomyces coelicolor A3(2) 246875_521_727 with other domain, from Streptomyces coelicolor A3(2) single domain, from Saccharopolyspora erythraea NRRL 2338 3653714_122_335 single domain, from Saccharopolyspora erythraea NRRL 2338 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory