Sites on a Tree

 

Download tree, alignment (240 x 716), positions, or descriptions, or see permanent link to this page, or start over.

Upload descriptions:
The table should be tab-delimited with the sequence identifier in the 1st column and the description in the 2nd column. Optionally, add fields named color and URL.

Select positions to show: in

Or see functional positions, see filtered positions, or see all positions.

Zoomed into a clade of 3 proteins, or see all 240 proteins. Position numbering is from BT2157.

Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

Find sequence pattern:

Highlight proteins:

4594548_352_539: with other domain, near sugar dehydrogenase, from Planctomyces maris DSM 8797 (has NEQ) 4614230_39_205: single domain, from Lentisphaera araneosa HTCC2155 (has NEQ) 6253107_21_166: single domain, from Chthoniobacter flavus Ellin428 (has NEQ) BT2157 has N at position 134 (alignment position 385)N134 4594548_352_539 has N63 EQ 4614230_39_205 has N42 EQ 6253107_21_166 has N16 EQ 4594548_352_539 and 2 similar proteins have N aligning to 134N BT2157 has E at position 164 (alignment position 438)E164 4594548_352_539 has N E82 Q 4614230_39_205 has N E60 Q 6253107_21_166 has N E34 Q 4594548_352_539 and 2 similar proteins have E aligning to 164E BT2157 has Q at position 166 (alignment position 440)Q166 4594548_352_539 has NE Q84 4614230_39_205 has NE Q62 6253107_21_166 has NE Q36 4594548_352_539 and 2 similar proteins have Q aligning to 166Q 4594548_352_539: with other domain, near sugar dehydrogenase, from Planctomyces maris DSM 8797 4594548_352_5394594548_352_539: with other domain, near sugar dehydrogenase, from Planctomyces maris DSM 8797 0.793 4614230_39_205: single domain, from Lentisphaera araneosa HTCC2155 4614230_39_2054614230_39_205: single domain, from Lentisphaera araneosa HTCC2155 6253107_21_166: single domain, from Chthoniobacter flavus Ellin428 6253107_21_1666253107_21_166: single domain, from Chthoniobacter flavus Ellin428 4594548_352_539: with other domain, near sugar dehydrogenase, from Planctomyces maris DSM 8797 (has NEQ)4594548_352_539 with other domain, near sugar dehydrogenase, from Planctomyces maris DSM 8797 4614230_39_205: single domain, from Lentisphaera araneosa HTCC2155 (has NEQ)4614230_39_205 single domain, from Lentisphaera araneosa HTCC2155 6253107_21_166: single domain, from Chthoniobacter flavus Ellin428 (has NEQ)6253107_21_166 single domain, from Chthoniobacter flavus Ellin428 0.5 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory