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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.793 4614230_39_205: single domain, from Lentisphaera araneosa HTCC2155 6253107_21_166: single domain, from Chthoniobacter flavus Ellin428 0.5 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 single domain, from Lentisphaera araneosa HTCC2155 4614230_39_205 single domain, from Lentisphaera araneosa HTCC2155 4614230_39_205 at #155 4614230_39_205 at #155 - 4614230_39_205 at #156 4614230_39_205 at #156 - 4614230_39_205 at #157 4614230_39_205 at #157 - 4614230_39_205 at #158 4614230_39_205 at #158 - 4614230_39_205 at #159 4614230_39_205 at #159 - 4614230_39_205 at #160 4614230_39_205 at #160 - 4614230_39_205 at #162 4614230_39_205 at #162 - 4614230_39_205 at #164 4614230_39_205 at #164 - 4614230_39_205 at #165 4614230_39_205 at #165 - 4614230_39_205 at #168 4614230_39_205 at #168 - 4614230_39_205 at #169 4614230_39_205 at #169 - 4614230_39_205 at #171 4614230_39_205 at #171 - 4614230_39_205 at #172 4614230_39_205 at #172 - 4614230_39_205 at #180 4614230_39_205 at #180 - 4614230_39_205 at #181 4614230_39_205 at #181 - 4614230_39_205 at #185 4614230_39_205 at #185 - 4614230_39_205 at #186 4614230_39_205 at #186 - 4614230_39_205 at #187 4614230_39_205 at #187 - 4614230_39_205 at #188 4614230_39_205 at #188 - 4614230_39_205 at #189 4614230_39_205 at #189 - 4614230_39_205 at #190 4614230_39_205 at #190 - 4614230_39_205 at #191 4614230_39_205 at #191 - 4614230_39_205 at #195 4614230_39_205 at #195 - 4614230_39_205 at #196 4614230_39_205 at #196 - 4614230_39_205 at #197: K2 4614230_39_205 at #197: K2 K 4614230_39_205 at #198: W3 4614230_39_205 at #198: W3 W 4614230_39_205 at #235: V4 4614230_39_205 at #235: V4 V 4614230_39_205 at #236: L5 4614230_39_205 at #236: L5 L 4614230_39_205 at #237: K6 4614230_39_205 at #237: K6 K 4614230_39_205 at #238: D7 4614230_39_205 at #238: D7 D 4614230_39_205 at #240: G8 4614230_39_205 at #240: G8 G 4614230_39_205 at #268: L9 4614230_39_205 at #268: L9 L 4614230_39_205 at #269: L10 4614230_39_205 at #269: L10 L 4614230_39_205 at #270: Y11 4614230_39_205 at #270: Y11 Y 4614230_39_205 at #294 4614230_39_205 at #294 - 4614230_39_205 at #295: P12 4614230_39_205 at #295: P12 P 4614230_39_205 at #296: S13 4614230_39_205 at #296: S13 S 4614230_39_205 at #297: E14 4614230_39_205 at #297: E14 E 4614230_39_205 at #298: K15 4614230_39_205 at #298: K15 K 4614230_39_205 at #299: P16 4614230_39_205 at #299: P16 P 4614230_39_205 at #300: G17 4614230_39_205 at #300: G17 G 4614230_39_205 at #301: Y18 4614230_39_205 at #301: Y18 Y 4614230_39_205 at #303: I19 4614230_39_205 at #303: I19 I 4614230_39_205 at #304: V20 4614230_39_205 at #304: V20 V 4614230_39_205 at #305: W21 4614230_39_205 at #305: W21 W 4614230_39_205 at #306: T22 4614230_39_205 at #306: T22 T 4614230_39_205 at #312: K23 4614230_39_205 at #312: K23 K 4614230_39_205 at #318: K24 4614230_39_205 at #318: K24 K 4614230_39_205 at #321: S25 4614230_39_205 at #321: S25 S 4614230_39_205 at #322: F26 4614230_39_205 at #322: F26 F 4614230_39_205 at #324: S27 4614230_39_205 at #324: S27 S 4614230_39_205 at #326: N28 4614230_39_205 at #326: N28 N 4614230_39_205 at #327: F29 4614230_39_205 at #327: F29 F 4614230_39_205 at #328: E30 4614230_39_205 at #328: E30 E 4614230_39_205 at #329: L31 4614230_39_205 at #329: L31 L 4614230_39_205 at #330: T32 4614230_39_205 at #330: T32 T 4614230_39_205 at #331: V33 4614230_39_205 at #331: V33 V 4614230_39_205 at #332: E34 4614230_39_205 at #332: E34 E 4614230_39_205 at #333: F35 4614230_39_205 at #333: F35 F 4614230_39_205 at #334: K36 4614230_39_205 at #334: K36 K 4614230_39_205 at #335: T37 4614230_39_205 at #335: T37 T 4614230_39_205 at #351: S38 4614230_39_205 at #351: S38 S 4614230_39_205 at #352: E39 4614230_39_205 at #352: E39 E 4614230_39_205 at #354: E40 4614230_39_205 at #354: E40 E 4614230_39_205 at #355: C41 4614230_39_205 at #355: C41 C 4614230_39_205 at #385: N42 4614230_39_205 at #385: N42 N 4614230_39_205 at #386: S43 4614230_39_205 at #386: S43 S 4614230_39_205 at #387: G44 4614230_39_205 at #387: G44 G 4614230_39_205 at #388: I45 4614230_39_205 at #388: I45 I 4614230_39_205 at #389: F46 4614230_39_205 at #389: F46 F 4614230_39_205 at #390: F47 4614230_39_205 at #390: F47 F 4614230_39_205 at #391: R48 4614230_39_205 at #391: R48 R 4614230_39_205 at #392: T49 4614230_39_205 at #392: T49 T 4614230_39_205 at #393: N50 4614230_39_205 at #393: N50 N 4614230_39_205 at #423 4614230_39_205 at #423 - 4614230_39_205 at #424 4614230_39_205 at #424 - 4614230_39_205 at #425: I51 4614230_39_205 at #425: I51 I 4614230_39_205 at #426: N52 4614230_39_205 at #426: N52 N 4614230_39_205 at #430: N53 4614230_39_205 at #430: N53 N 4614230_39_205 at #431: P54 4614230_39_205 at #431: P54 P 4614230_39_205 at #432: V55 4614230_39_205 at #432: V55 V 4614230_39_205 at #433: Q56 4614230_39_205 at #433: Q56 Q 4614230_39_205 at #434: E57 4614230_39_205 at #434: E57 E 4614230_39_205 at #435: G58 4614230_39_205 at #435: G58 G 4614230_39_205 at #436: F59 4614230_39_205 at #436: F59 F 4614230_39_205 at #438: E60 4614230_39_205 at #438: E60 E 4614230_39_205 at #439: I61 4614230_39_205 at #439: I61 I 4614230_39_205 at #440: Q62 4614230_39_205 at #440: Q62 Q 4614230_39_205 at #441: V63 4614230_39_205 at #441: V63 V 4614230_39_205 at #442: A64 4614230_39_205 at #442: A64 A 4614230_39_205 at #443: S65 4614230_39_205 at #443: S65 S 4614230_39_205 at #450: P66 4614230_39_205 at #450: P66 P 4614230_39_205 at #451: G67 4614230_39_205 at #451: G67 G 4614230_39_205 at #452: L68 4614230_39_205 at #452: L68 L 4614230_39_205 at #453: Y69 4614230_39_205 at #453: Y69 Y 4614230_39_205 at #475 4614230_39_205 at #475 - 4614230_39_205 at #476: N70 4614230_39_205 at #476: N70 N 4614230_39_205 at #477: G71 4614230_39_205 at #477: G71 G 4614230_39_205 at #478: K72 4614230_39_205 at #478: K72 K 4614230_39_205 at #479: H73 4614230_39_205 at #479: H73 H 4614230_39_205 at #480: V74 4614230_39_205 at #480: V74 V 4614230_39_205 at #481: V75 4614230_39_205 at #481: V75 V 4614230_39_205 at #482: G76 4614230_39_205 at #482: G76 G 4614230_39_205 at #483: S77 4614230_39_205 at #483: S77 S 4614230_39_205 at #484: L78 4614230_39_205 at #484: L78 L 4614230_39_205 at #485: Y79 4614230_39_205 at #485: Y79 Y 4614230_39_205 at #486: D80 4614230_39_205 at #486: D80 D 4614230_39_205 at #487 4614230_39_205 at #487 - 4614230_39_205 at #530 4614230_39_205 at #530 - 4614230_39_205 at #532 4614230_39_205 at #532 - 4614230_39_205 at #533: A81 4614230_39_205 at #533: A81 A 4614230_39_205 at #534: K82 4614230_39_205 at #534: K82 K 4614230_39_205 at #535: E83 4614230_39_205 at #535: E83 E 4614230_39_205 at #544: P84 4614230_39_205 at #544: P84 P 4614230_39_205 at #545: S85 4614230_39_205 at #545: S85 S 4614230_39_205 at #548: E86 4614230_39_205 at #548: E86 E 4614230_39_205 at #549: I87 4614230_39_205 at #549: I87 I 4614230_39_205 at #550: A88 4614230_39_205 at #550: A88 A 4614230_39_205 at #551: V89 4614230_39_205 at #551: V89 V 4614230_39_205 at #552: K90 4614230_39_205 at #552: K90 K 4614230_39_205 at #553: P91 4614230_39_205 at #553: P91 P 4614230_39_205 at #554: D92 4614230_39_205 at #554: D92 D 4614230_39_205 at #555: G93 4614230_39_205 at #555: G93 G 4614230_39_205 at #556: E94 4614230_39_205 at #556: E94 E 4614230_39_205 at #557: W95 4614230_39_205 at #557: W95 W 4614230_39_205 at #558: N96 4614230_39_205 at #558: N96 N 4614230_39_205 at #559: T97 4614230_39_205 at #559: T97 T 4614230_39_205 at #560: M98 4614230_39_205 at #560: M98 M 4614230_39_205 at #561: V99 4614230_39_205 at #561: V99 V 4614230_39_205 at #562: L100 4614230_39_205 at #562: L100 L 4614230_39_205 at #565: T101 4614230_39_205 at #565: T101 T 4614230_39_205 at #566: C102 4614230_39_205 at #566: C102 C 4614230_39_205 at #568: K103 4614230_39_205 at #568: K103 K 4614230_39_205 at #570: G104 4614230_39_205 at #570: G104 G 4614230_39_205 at #571: P105 4614230_39_205 at #571: P105 P 4614230_39_205 at #572: K106 4614230_39_205 at #572: K106 K 4614230_39_205 at #588: I107 4614230_39_205 at #588: I107 I 4614230_39_205 at #589: K108 4614230_39_205 at #589: K108 K 4614230_39_205 at #592: V109 4614230_39_205 at #592: V109 V 4614230_39_205 at #594: V110 4614230_39_205 at #594: V110 V 4614230_39_205 at #595: L111 4614230_39_205 at #595: L111 L 4614230_39_205 at #596: N112 4614230_39_205 at #596: N112 N 4614230_39_205 at #598: G113 4614230_39_205 at #598: G113 G 4614230_39_205 at #599: V114 4614230_39_205 at #599: V114 V 4614230_39_205 at #600: E115 4614230_39_205 at #600: E115 E 4614230_39_205 at #601: V116 4614230_39_205 at #601: V116 V 4614230_39_205 at #602: Q117 4614230_39_205 at #602: Q117 Q 4614230_39_205 at #603: N118 4614230_39_205 at #603: N118 N 4614230_39_205 at #604: L119 4614230_39_205 at #604: L119 L 4614230_39_205 at #605: N120 4614230_39_205 at #605: N120 N 4614230_39_205 at #606: I121 4614230_39_205 at #606: I121 I 4614230_39_205 at #607: N122 4614230_39_205 at #607: N122 N 4614230_39_205 at #608: D123 4614230_39_205 at #608: D123 D 4614230_39_205 at #609: W124 4614230_39_205 at #609: W124 W 4614230_39_205 at #610: N125 4614230_39_205 at #610: N125 N 4614230_39_205 at #611: T126 4614230_39_205 at #611: T126 T 4614230_39_205 at #612: A127 4614230_39_205 at #612: A127 A 4614230_39_205 at #613: N128 4614230_39_205 at #613: N128 N 4614230_39_205 at #614: K129 4614230_39_205 at #614: K129 K 4614230_39_205 at #615: N130 4614230_39_205 at #615: N130 N 4614230_39_205 at #616: P131 4614230_39_205 at #616: P131 P 4614230_39_205 at #640: D144 4614230_39_205 at #640: D144 D 4614230_39_205 at #641: L145 4614230_39_205 at #641: L145 L 4614230_39_205 at #642: P146 4614230_39_205 at #642: P146 P 4614230_39_205 at #643: H147 4614230_39_205 at #643: H147 H 4614230_39_205 at #644: N148 4614230_39_205 at #644: N148 N 4614230_39_205 at #645: G149 4614230_39_205 at #645: G149 G 4614230_39_205 at #646: R150 4614230_39_205 at #646: R150 R 4614230_39_205 at #647: I151 4614230_39_205 at #647: I151 I 4614230_39_205 at #648: G152 4614230_39_205 at #648: G152 G 4614230_39_205 at #649: V153 4614230_39_205 at #649: V153 V 4614230_39_205 at #650: Q154 4614230_39_205 at #650: Q154 Q 4614230_39_205 at #653: Y155 4614230_39_205 at #653: Y155 Y 4614230_39_205 at #654: H156 4614230_39_205 at #654: H156 H 4614230_39_205 at #655: G157 4614230_39_205 at #655: G157 G 4614230_39_205 at #668: Q158 4614230_39_205 at #668: Q158 Q 4614230_39_205 at #689: P159 4614230_39_205 at #689: P159 P 4614230_39_205 at #690: V160 4614230_39_205 at #690: V160 V 4614230_39_205 at #691: W161 4614230_39_205 at #691: W161 W 4614230_39_205 at #694: Y162 4614230_39_205 at #694: Y162 Y 4614230_39_205 at #695: R163 4614230_39_205 at #695: R163 R 4614230_39_205 at #696: K164 4614230_39_205 at #696: K164 K 4614230_39_205 at #697: L165 4614230_39_205 at #697: L165 L 4614230_39_205 at #698: S166 4614230_39_205 at #698: S166 S 4614230_39_205 at #699: I167 4614230_39_205 at #699: I167 I 4614230_39_205 at #700 4614230_39_205 at #700 - single domain, from Chthoniobacter flavus Ellin428 6253107_21_166 single domain, from Chthoniobacter flavus Ellin428 6253107_21_166 at #155 6253107_21_166 at #155 - 6253107_21_166 at #156 6253107_21_166 at #156 - 6253107_21_166 at #157 6253107_21_166 at #157 - 6253107_21_166 at #158 6253107_21_166 at #158 - 6253107_21_166 at #159 6253107_21_166 at #159 - 6253107_21_166 at #160 6253107_21_166 at #160 - 6253107_21_166 at #162 6253107_21_166 at #162 - 6253107_21_166 at #164 6253107_21_166 at #164 - 6253107_21_166 at #165 6253107_21_166 at #165 - 6253107_21_166 at #168 6253107_21_166 at #168 - 6253107_21_166 at #169 6253107_21_166 at #169 - 6253107_21_166 at #171 6253107_21_166 at #171 - 6253107_21_166 at #172 6253107_21_166 at #172 - 6253107_21_166 at #180 6253107_21_166 at #180 - 6253107_21_166 at #181 6253107_21_166 at #181 - 6253107_21_166 at #185 6253107_21_166 at #185 - 6253107_21_166 at #186 6253107_21_166 at #186 - 6253107_21_166 at #187 6253107_21_166 at #187 - 6253107_21_166 at #188 6253107_21_166 at #188 - 6253107_21_166 at #189 6253107_21_166 at #189 - 6253107_21_166 at #190 6253107_21_166 at #190 - 6253107_21_166 at #191 6253107_21_166 at #191 - 6253107_21_166 at #195 6253107_21_166 at #195 - 6253107_21_166 at #196 6253107_21_166 at #196 - 6253107_21_166 at #197 6253107_21_166 at #197 - 6253107_21_166 at #198 6253107_21_166 at #198 - 6253107_21_166 at #235 6253107_21_166 at #235 - 6253107_21_166 at #236 6253107_21_166 at #236 - 6253107_21_166 at #237 6253107_21_166 at #237 - 6253107_21_166 at #238 6253107_21_166 at #238 - 6253107_21_166 at #240 6253107_21_166 at #240 - 6253107_21_166 at #268 6253107_21_166 at #268 - 6253107_21_166 at #269 6253107_21_166 at #269 - 6253107_21_166 at #270 6253107_21_166 at #270 - 6253107_21_166 at #294 6253107_21_166 at #294 - 6253107_21_166 at #295 6253107_21_166 at #295 - 6253107_21_166 at #296 6253107_21_166 at #296 - 6253107_21_166 at #297 6253107_21_166 at #297 - 6253107_21_166 at #298 6253107_21_166 at #298 - 6253107_21_166 at #299 6253107_21_166 at #299 - 6253107_21_166 at #300 6253107_21_166 at #300 - 6253107_21_166 at #301 6253107_21_166 at #301 - 6253107_21_166 at #303 6253107_21_166 at #303 - 6253107_21_166 at #304 6253107_21_166 at #304 - 6253107_21_166 at #305 6253107_21_166 at #305 - 6253107_21_166 at #306 6253107_21_166 at #306 - 6253107_21_166 at #312 6253107_21_166 at #312 - 6253107_21_166 at #318 6253107_21_166 at #318 - 6253107_21_166 at #321 6253107_21_166 at #321 - 6253107_21_166 at #322 6253107_21_166 at #322 - 6253107_21_166 at #324 6253107_21_166 at #324 - 6253107_21_166 at #326 6253107_21_166 at #326 - 6253107_21_166 at #327: F1 6253107_21_166 at #327: F1 F 6253107_21_166 at #328: E2 6253107_21_166 at #328: E2 E 6253107_21_166 at #329: L3 6253107_21_166 at #329: L3 L 6253107_21_166 at #330: H4 6253107_21_166 at #330: H4 H 6253107_21_166 at #331: S5 6253107_21_166 at #331: S5 S 6253107_21_166 at #332: R6 6253107_21_166 at #332: R6 R 6253107_21_166 at #333: S7 6253107_21_166 at #333: S7 S 6253107_21_166 at #334: R8 6253107_21_166 at #334: R8 R 6253107_21_166 at #335: F9 6253107_21_166 at #335: F9 F 6253107_21_166 at #351: A12 6253107_21_166 at #351: A12 A 6253107_21_166 at #352: K13 6253107_21_166 at #352: K13 K 6253107_21_166 at #354: E14 6253107_21_166 at #354: E14 E 6253107_21_166 at #355: S15 6253107_21_166 at #355: S15 S 6253107_21_166 at #385: N16 6253107_21_166 at #385: N16 N 6253107_21_166 at #386: S17 6253107_21_166 at #386: S17 S 6253107_21_166 at #387: G18 6253107_21_166 at #387: G18 G 6253107_21_166 at #388: V19 6253107_21_166 at #388: V19 V 6253107_21_166 at #389: F20 6253107_21_166 at #389: F20 F 6253107_21_166 at #390: L21 6253107_21_166 at #390: L21 L 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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory