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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.899 11294916_26_207: single domain, from Planctomyces brasiliensis DSM 5305 2224519_22_203: single domain, from Solibacter usitatus Ellin6076 1 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 single domain, from Planctomyces brasiliensis DSM 5305 11294916_26_207 single domain, from Planctomyces brasiliensis DSM 5305 11294916_26_207 at #155: K1 11294916_26_207 at #155: K1 K 11294916_26_207 at #156: W2 11294916_26_207 at #156: W2 W 11294916_26_207 at #157: Q3 11294916_26_207 at #157: Q3 Q 11294916_26_207 at #158: N4 11294916_26_207 at #158: N4 N 11294916_26_207 at #159: L5 11294916_26_207 at #159: L5 L 11294916_26_207 at #160: L6 11294916_26_207 at #160: L6 L 11294916_26_207 at #162: P7 11294916_26_207 at #162: P7 P 11294916_26_207 at #164: N8 11294916_26_207 at #164: N8 N 11294916_26_207 at #165: N9 11294916_26_207 at #165: N9 N 11294916_26_207 at #168: R10 11294916_26_207 at #168: R10 R 11294916_26_207 at #169: L11 11294916_26_207 at #169: L11 L 11294916_26_207 at #171: D12 11294916_26_207 at #171: D12 D 11294916_26_207 at #172: A13 11294916_26_207 at #172: A13 A 11294916_26_207 at #180: W15 11294916_26_207 at #180: W15 W 11294916_26_207 at #181: S16 11294916_26_207 at #181: S16 S 11294916_26_207 at #185: T17 11294916_26_207 at #185: T17 T 11294916_26_207 at #186: S18 11294916_26_207 at #186: S18 S 11294916_26_207 at #187: G19 11294916_26_207 at #187: G19 G 11294916_26_207 at #188: N20 11294916_26_207 at #188: N20 N 11294916_26_207 at #189: W21 11294916_26_207 at #189: W21 W 11294916_26_207 at #190: K22 11294916_26_207 at #190: K22 K 11294916_26_207 at #191: I23 11294916_26_207 at #191: I23 I 11294916_26_207 at #195: N24 11294916_26_207 at #195: N24 N 11294916_26_207 at #196 11294916_26_207 at #196 - 11294916_26_207 at #197 11294916_26_207 at #197 - 11294916_26_207 at #198 11294916_26_207 at #198 - 11294916_26_207 at #235 11294916_26_207 at #235 - 11294916_26_207 at #236 11294916_26_207 at #236 - 11294916_26_207 at #237: D25 11294916_26_207 at #237: D25 D 11294916_26_207 at #238: D26 11294916_26_207 at #238: D26 D 11294916_26_207 at #240: G27 11294916_26_207 at #240: G27 G 11294916_26_207 at #268: V28 11294916_26_207 at #268: V28 V 11294916_26_207 at #269: V29 11294916_26_207 at #269: V29 V 11294916_26_207 at #270: S30 11294916_26_207 at #270: S30 S 11294916_26_207 at #294: S38 11294916_26_207 at #294: S38 S 11294916_26_207 at #295: G39 11294916_26_207 at #295: G39 G 11294916_26_207 at #296: W40 11294916_26_207 at #296: W40 W 11294916_26_207 at #297: T41 11294916_26_207 at #297: T41 T 11294916_26_207 at #298: R42 11294916_26_207 at #298: R42 R 11294916_26_207 at #299: Y43 11294916_26_207 at #299: Y43 Y 11294916_26_207 at #300: D44 11294916_26_207 at #300: D44 D 11294916_26_207 at #301: A45 11294916_26_207 at #301: A45 A 11294916_26_207 at #303: Y46 11294916_26_207 at #303: Y46 Y 11294916_26_207 at #304: L47 11294916_26_207 at #304: L47 L 11294916_26_207 at #305: W48 11294916_26_207 at #305: W48 W 11294916_26_207 at #306: H49 11294916_26_207 at #306: H49 H 11294916_26_207 at #312: E50 11294916_26_207 at #312: E50 E 11294916_26_207 at #318: K51 11294916_26_207 at #318: K51 K 11294916_26_207 at #321: T52 11294916_26_207 at #321: T52 T 11294916_26_207 at #322: Y53 11294916_26_207 at #322: Y53 Y 11294916_26_207 at #324: D54 11294916_26_207 at #324: D54 D 11294916_26_207 at #326: D55 11294916_26_207 at #326: D55 D 11294916_26_207 at #327: F56 11294916_26_207 at #327: F56 F 11294916_26_207 at #328: E57 11294916_26_207 at #328: E57 E 11294916_26_207 at #329: I58 11294916_26_207 at #329: I58 I 11294916_26_207 at #330: E59 11294916_26_207 at #330: E59 E 11294916_26_207 at #331: F60 11294916_26_207 at #331: F60 F 11294916_26_207 at #332: D61 11294916_26_207 at #332: D61 D 11294916_26_207 at #333: Y62 11294916_26_207 at #333: Y62 Y 11294916_26_207 at #334: K63 11294916_26_207 at #334: K63 K 11294916_26_207 at #335: V64 11294916_26_207 at #335: V64 V 11294916_26_207 at #351: E65 11294916_26_207 at #351: E65 E 11294916_26_207 at #352: E66 11294916_26_207 at #352: E66 E 11294916_26_207 at #354: K67 11294916_26_207 at #354: K67 K 11294916_26_207 at #355: G68 11294916_26_207 at #355: G68 G 11294916_26_207 at #385: N69 11294916_26_207 at #385: N69 N 11294916_26_207 at #386: S70 11294916_26_207 at #386: S70 S 11294916_26_207 at #387: G71 11294916_26_207 at #387: G71 G 11294916_26_207 at #388: F72 11294916_26_207 at #388: F72 F 11294916_26_207 at #389: Y73 11294916_26_207 at #389: Y73 Y 11294916_26_207 at #390: F74 11294916_26_207 at #390: F74 F 11294916_26_207 at #391: N75 11294916_26_207 at #391: N75 N 11294916_26_207 at #392: V76 11294916_26_207 at #392: V76 V 11294916_26_207 at #393: V77 11294916_26_207 at #393: V77 V 11294916_26_207 at #423 11294916_26_207 at #423 - 11294916_26_207 at #424: D78 11294916_26_207 at #424: D78 D 11294916_26_207 at #425: K79 11294916_26_207 at #425: K79 K 11294916_26_207 at #426: T80 11294916_26_207 at #426: T80 T 11294916_26_207 at #430: N81 11294916_26_207 at #430: N81 N 11294916_26_207 at #431: P82 11294916_26_207 at #431: P82 P 11294916_26_207 at #432: V83 11294916_26_207 at #432: V83 V 11294916_26_207 at #433: A84 11294916_26_207 at #433: A84 A 11294916_26_207 at #434: E85 11294916_26_207 at #434: E85 E 11294916_26_207 at #435: G86 11294916_26_207 at #435: G86 G 11294916_26_207 at #436: I87 11294916_26_207 at #436: I87 I 11294916_26_207 at #438: E88 11294916_26_207 at #438: E88 E 11294916_26_207 at #439: V89 11294916_26_207 at #439: V89 V 11294916_26_207 at #440: Q90 11294916_26_207 at #440: Q90 Q 11294916_26_207 at #441: I91 11294916_26_207 at #441: I91 I 11294916_26_207 at #442: Y92 11294916_26_207 at #442: Y92 Y 11294916_26_207 at #443: D93 11294916_26_207 at #443: D93 D 11294916_26_207 at #450: S94 11294916_26_207 at #450: S94 S 11294916_26_207 at #451: H95 11294916_26_207 at #451: H95 H 11294916_26_207 at #452: D96 11294916_26_207 at #452: D96 D 11294916_26_207 at #453: Q97 11294916_26_207 at #453: Q97 Q 11294916_26_207 at #475: K99 11294916_26_207 at #475: K99 K 11294916_26_207 at #476: L100 11294916_26_207 at #476: L100 L 11294916_26_207 at #477: T101 11294916_26_207 at #477: T101 T 11294916_26_207 at #478: D102 11294916_26_207 at #478: D102 D 11294916_26_207 at #479: H103 11294916_26_207 at #479: H103 H 11294916_26_207 at #480: T104 11294916_26_207 at #480: T104 T 11294916_26_207 at #481: S105 11294916_26_207 at #481: S105 S 11294916_26_207 at #482: G106 11294916_26_207 at #482: G106 G 11294916_26_207 at #483: G107 11294916_26_207 at #483: G107 G 11294916_26_207 at #484: V108 11294916_26_207 at #484: V108 V 11294916_26_207 at #485: I109 11294916_26_207 at #485: I109 I 11294916_26_207 at #486 11294916_26_207 at #486 - 11294916_26_207 at #487 11294916_26_207 at #487 - 11294916_26_207 at #530 11294916_26_207 at #530 - 11294916_26_207 at #532: P110 11294916_26_207 at #532: P110 P 11294916_26_207 at #533: G111 11294916_26_207 at #533: G111 G 11294916_26_207 at #534: V112 11294916_26_207 at #534: V112 V 11294916_26_207 at #535: S113 11294916_26_207 at #535: S113 S 11294916_26_207 at #544: P114 11294916_26_207 at #544: P114 P 11294916_26_207 at #545: Q115 11294916_26_207 at #545: Q115 Q 11294916_26_207 at #548: K116 11294916_26_207 at #548: K116 K 11294916_26_207 at #549: N117 11294916_26_207 at #549: N117 N 11294916_26_207 at #550: A118 11294916_26_207 at #550: A118 A 11294916_26_207 at #551: A119 11294916_26_207 at #551: A119 A 11294916_26_207 at #552: N120 11294916_26_207 at #552: N120 N 11294916_26_207 at #553: P121 11294916_26_207 at #553: P121 P 11294916_26_207 at #554: A122 11294916_26_207 at #554: A122 A 11294916_26_207 at #555: G123 11294916_26_207 at #555: G123 G 11294916_26_207 at #556: Q124 11294916_26_207 at #556: Q124 Q 11294916_26_207 at #557: W125 11294916_26_207 at #557: W125 W 11294916_26_207 at #558: N126 11294916_26_207 at #558: N126 N 11294916_26_207 at #559: T127 11294916_26_207 at #559: T127 T 11294916_26_207 at #560: F128 11294916_26_207 at #560: F128 F 11294916_26_207 at #561: H129 11294916_26_207 at #561: H129 H 11294916_26_207 at #562: I130 11294916_26_207 at #562: I130 I 11294916_26_207 at #565: T131 11294916_26_207 at #565: T131 T 11294916_26_207 at #566: V132 11294916_26_207 at #566: V132 V 11294916_26_207 at #568: R133 11294916_26_207 at #568: R133 R 11294916_26_207 at #570: G134 11294916_26_207 at #570: G134 G 11294916_26_207 at #571: E135 11294916_26_207 at #571: E135 E 11294916_26_207 at #572: K136 11294916_26_207 at #572: K136 K 11294916_26_207 at #588: L137 11294916_26_207 at #588: L137 L 11294916_26_207 at #589: T138 11294916_26_207 at #589: T138 T 11294916_26_207 at #592: V139 11294916_26_207 at #592: V139 V 11294916_26_207 at #594: K140 11294916_26_207 at #594: K140 K 11294916_26_207 at #595: L141 11294916_26_207 at #595: L141 L 11294916_26_207 at #596: N142 11294916_26_207 at #596: N142 N 11294916_26_207 at #598: G143 11294916_26_207 at #598: G143 G 11294916_26_207 at #599: Q144 11294916_26_207 at #599: Q144 Q 11294916_26_207 at #600: V145 11294916_26_207 at #600: V145 V 11294916_26_207 at #601: V146 11294916_26_207 at #601: V146 V 11294916_26_207 at #602: N147 11294916_26_207 at #602: N147 N 11294916_26_207 at #603: E148 11294916_26_207 at #603: E148 E 11294916_26_207 at #604: V149 11294916_26_207 at #604: V149 V 11294916_26_207 at #605: D150 11294916_26_207 at #605: D150 D 11294916_26_207 at #606: L151 11294916_26_207 at #606: L151 L 11294916_26_207 at #607: E152 11294916_26_207 at #607: E152 E 11294916_26_207 at #608: Q153 11294916_26_207 at #608: Q153 Q 11294916_26_207 at #609: G154 11294916_26_207 at #609: G154 G 11294916_26_207 at #610: R155 11294916_26_207 at #610: R155 R 11294916_26_207 at #611: L156 11294916_26_207 at #611: L156 L 11294916_26_207 at #612: A157 11294916_26_207 at #612: A157 A 11294916_26_207 at #613: D158 11294916_26_207 at #613: D158 D 11294916_26_207 at #614: R159 11294916_26_207 at #614: R159 R 11294916_26_207 at #615 11294916_26_207 at #615 - 11294916_26_207 at #616 11294916_26_207 at #616 - 11294916_26_207 at #640 11294916_26_207 at #640 - 11294916_26_207 at #641 11294916_26_207 at #641 - 11294916_26_207 at #642: P160 11294916_26_207 at #642: P160 P 11294916_26_207 at #643: R161 11294916_26_207 at #643: R161 R 11294916_26_207 at #644: S162 11294916_26_207 at #644: S162 S 11294916_26_207 at #645: G163 11294916_26_207 at #645: G163 G 11294916_26_207 at #646: M164 11294916_26_207 at #646: M164 M 11294916_26_207 at #647: I165 11294916_26_207 at #647: I165 I 11294916_26_207 at #648: G166 11294916_26_207 at #648: G166 G 11294916_26_207 at #649: F167 11294916_26_207 at #649: F167 F 11294916_26_207 at #650: Q168 11294916_26_207 at #650: Q168 Q 11294916_26_207 at #653: D169 11294916_26_207 at #653: D169 D 11294916_26_207 at #654: H170 11294916_26_207 at #654: H170 H 11294916_26_207 at #655: G171 11294916_26_207 at #655: G171 G 11294916_26_207 at #668: L172 11294916_26_207 at #668: L172 L 11294916_26_207 at #689: P173 11294916_26_207 at #689: P173 P 11294916_26_207 at #690: L174 11294916_26_207 at #690: L174 L 11294916_26_207 at #691: S175 11294916_26_207 at #691: S175 S 11294916_26_207 at #694: L176 11294916_26_207 at #694: L176 L 11294916_26_207 at #695: R177 11294916_26_207 at #695: R177 R 11294916_26_207 at #696: N178 11294916_26_207 at #696: N178 N 11294916_26_207 at #697: I179 11294916_26_207 at #697: I179 I 11294916_26_207 at #698: R180 11294916_26_207 at #698: R180 R 11294916_26_207 at #699: I181 11294916_26_207 at #699: I181 I 11294916_26_207 at #700: R182 11294916_26_207 at #700: R182 R single domain, from Solibacter usitatus Ellin6076 2224519_22_203 single domain, from Solibacter usitatus Ellin6076 2224519_22_203 at #155 2224519_22_203 at #155 - 2224519_22_203 at #156 2224519_22_203 at #156 - 2224519_22_203 at #157 2224519_22_203 at #157 - 2224519_22_203 at #158 2224519_22_203 at #158 - 2224519_22_203 at #159: L3 2224519_22_203 at #159: L3 L 2224519_22_203 at #160: L4 2224519_22_203 at #160: L4 L 2224519_22_203 at #162: P5 2224519_22_203 at #162: P5 P 2224519_22_203 at #164: D6 2224519_22_203 at #164: D6 D 2224519_22_203 at #165: A7 2224519_22_203 at #165: A7 A 2224519_22_203 at #168: S8 2224519_22_203 at #168: S8 S 2224519_22_203 at #169: L9 2224519_22_203 at #169: L9 L 2224519_22_203 at #171: K10 2224519_22_203 at #171: K10 K 2224519_22_203 at #172: G11 2224519_22_203 at #172: G11 G 2224519_22_203 at #180: W12 2224519_22_203 at #180: W12 W 2224519_22_203 at #181: T13 2224519_22_203 at #181: T13 T 2224519_22_203 at #185: R14 2224519_22_203 at #185: R14 R 2224519_22_203 at #186: I15 2224519_22_203 at #186: I15 I 2224519_22_203 at #187 2224519_22_203 at #187 - 2224519_22_203 at #188 2224519_22_203 at #188 - 2224519_22_203 at #189 2224519_22_203 at #189 - 2224519_22_203 at #190: P16 2224519_22_203 at #190: P16 P 2224519_22_203 at #191: I17 2224519_22_203 at #191: I17 I 2224519_22_203 at #195: P18 2224519_22_203 at #195: P18 P 2224519_22_203 at #196: P19 2224519_22_203 at #196: P19 P 2224519_22_203 at #197 2224519_22_203 at #197 - 2224519_22_203 at #198 2224519_22_203 at #198 - 2224519_22_203 at #235 2224519_22_203 at #235 - 2224519_22_203 at #236 2224519_22_203 at #236 - 2224519_22_203 at #237: T20 2224519_22_203 at #237: T20 T 2224519_22_203 at #238: D21 2224519_22_203 at #238: D21 D 2224519_22_203 at #240: G22 2224519_22_203 at #240: G22 G 2224519_22_203 at #268: T37 2224519_22_203 at #268: T37 T 2224519_22_203 at #269: L38 2224519_22_203 at #269: L38 L 2224519_22_203 at #270: V39 2224519_22_203 at #270: V39 V 2224519_22_203 at #294: C40 2224519_22_203 at #294: C40 C 2224519_22_203 at #295: M41 2224519_22_203 at #295: M41 M 2224519_22_203 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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory