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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.910 0.034 0.771 0.911 10262249_29_210: single domain, from Spirosoma linguale DSM 74 0.455 0.672 4591527_43_215: single domain, from Planctomyces maris DSM 8797 0.993 2223153_25_190: single domain, from Solibacter usitatus Ellin6076 0.910 4908135_36_246: single domain, from Gemmata obscuriglobus UQM 2246 0.878 554351_85_257: single domain, from Pirellula sp. 1 11269824_44_215: single domain, from Isosphaera pallida IS1B, ATCC 43644 0.974 6253341_25_206: single domain, from Chthoniobacter flavus Ellin428 0.905 2764129_27_207: single domain, from Blastopirellula marina DSM 3645 6004371_23_210: single domain, from Verrucomicrobium spinosum DSM 4136 0.613 2221107_28_212: with other domain, from Solibacter usitatus Ellin6076 5646913_28_225: with other domain, from Opitutus terrae PB90-1 0.594 11272068_67_249: single domain, from Isosphaera pallida IS1B, ATCC 43644 0.974 3722502_28_193: with other domain, from Parabacteroides distasonis ATCC 8503 4262859_41_193: with other domain, from Bacteroides uniformis ATCC 8492 11292681_28_217: single domain, from Planctomyces brasiliensis DSM 5305 1 /site single domain, from Spirosoma linguale DSM 74 10262249_29_210 single domain, from Spirosoma linguale DSM 74 single domain, from Planctomyces maris DSM 8797 4591527_43_215 single domain, from Planctomyces maris DSM 8797 single domain, from Solibacter usitatus Ellin6076 2223153_25_190 single domain, from Solibacter usitatus Ellin6076 single domain, from Gemmata obscuriglobus UQM 2246 4908135_36_246 single domain, from Gemmata obscuriglobus UQM 2246 single domain, from Pirellula sp. 1 554351_85_257 single domain, from Pirellula sp. 1 single domain, from Isosphaera pallida IS1B, ATCC 43644 11269824_44_215 single domain, from Isosphaera pallida IS1B, ATCC 43644 single domain, from Chthoniobacter flavus Ellin428 6253341_25_206 single domain, from Chthoniobacter flavus Ellin428 single domain, from Blastopirellula marina DSM 3645 2764129_27_207 single domain, from Blastopirellula marina DSM 3645 single domain, from Verrucomicrobium spinosum DSM 4136 6004371_23_210 single domain, from Verrucomicrobium spinosum DSM 4136 with other domain, from Solibacter usitatus Ellin6076 2221107_28_212 with other domain, from Solibacter usitatus Ellin6076 with other domain, from Opitutus terrae PB90-1 5646913_28_225 with other domain, from Opitutus terrae PB90-1 single domain, from Isosphaera pallida IS1B, ATCC 43644 11272068_67_249 single domain, from Isosphaera pallida IS1B, ATCC 43644 with other domain, from Parabacteroides distasonis ATCC 8503 3722502_28_193 with other domain, from Parabacteroides distasonis ATCC 8503 with other domain, from Bacteroides uniformis ATCC 8492 4262859_41_193 with other domain, from Bacteroides uniformis ATCC 8492 single domain, from Planctomyces brasiliensis DSM 5305 11292681_28_217 single domain, from Planctomyces brasiliensis DSM 5305 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory