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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.878 554351_85_257: single domain, from Pirellula sp. 1 11269824_44_215: single domain, from Isosphaera pallida IS1B, ATCC 43644 0.5 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 single domain, from Pirellula sp. 1 554351_85_257 single domain, from Pirellula sp. 1 554351_85_257 at #155: K1 554351_85_257 at #155: K1 K 554351_85_257 at #156: W2 554351_85_257 at #156: W2 W 554351_85_257 at #157: T3 554351_85_257 at #157: T3 T 554351_85_257 at #158: T4 554351_85_257 at #158: T4 T 554351_85_257 at #159: L5 554351_85_257 at #159: L5 L 554351_85_257 at #160: F6 554351_85_257 at #160: F6 F 554351_85_257 at #162: D7 554351_85_257 at #162: D7 D 554351_85_257 at #164: G8 554351_85_257 at #164: G8 G 554351_85_257 at #165: E9 554351_85_257 at #165: E9 E 554351_85_257 at #168: S10 554351_85_257 at #168: S10 S 554351_85_257 at #169: L11 554351_85_257 at #169: L11 L 554351_85_257 at #171: E12 554351_85_257 at #171: E12 E 554351_85_257 at #172: G13 554351_85_257 at #172: G13 G 554351_85_257 at #180: W14 554351_85_257 at #180: W14 W 554351_85_257 at #181: E15 554351_85_257 at #181: E15 E 554351_85_257 at #185: K16 554351_85_257 at #185: K16 K 554351_85_257 at #186: V17 554351_85_257 at #186: V17 V 554351_85_257 at #187: G18 554351_85_257 at #187: G18 G 554351_85_257 at #188: R19 554351_85_257 at #188: R19 R 554351_85_257 at #189: D20 554351_85_257 at #189: D20 D 554351_85_257 at #190 554351_85_257 at #190 - 554351_85_257 at #191 554351_85_257 at #191 - 554351_85_257 at #195: D21 554351_85_257 at #195: D21 D 554351_85_257 at #196: S22 554351_85_257 at #196: S22 S 554351_85_257 at #197: K23 554351_85_257 at #197: K23 K 554351_85_257 at #198: W24 554351_85_257 at #198: W24 W 554351_85_257 at #235: E25 554351_85_257 at #235: E25 E 554351_85_257 at #236: V26 554351_85_257 at #236: V26 V 554351_85_257 at #237: V27 554351_85_257 at #237: V27 V 554351_85_257 at #238: D28 554351_85_257 at #238: D28 D 554351_85_257 at #240: G29 554351_85_257 at #240: G29 G 554351_85_257 at #268: V30 554351_85_257 at #268: V30 V 554351_85_257 at #269: I31 554351_85_257 at #269: I31 I 554351_85_257 at #270: K32 554351_85_257 at #270: K32 K 554351_85_257 at #294 554351_85_257 at #294 - 554351_85_257 at #295: G33 554351_85_257 at #295: G33 G 554351_85_257 at #296: T34 554351_85_257 at #296: T34 T 554351_85_257 at #297: G35 554351_85_257 at #297: G35 G 554351_85_257 at #298: G36 554351_85_257 at #298: G36 G 554351_85_257 at #299: V37 554351_85_257 at #299: V37 V 554351_85_257 at #300: S38 554351_85_257 at #300: S38 S 554351_85_257 at #301: M39 554351_85_257 at #301: M39 M 554351_85_257 at #303: L40 554351_85_257 at #303: L40 L 554351_85_257 at #304: V41 554351_85_257 at #304: V41 V 554351_85_257 at #305: N42 554351_85_257 at #305: N42 N 554351_85_257 at #306: T43 554351_85_257 at #306: T43 T 554351_85_257 at #312: S44 554351_85_257 at #312: S44 S 554351_85_257 at #318: G45 554351_85_257 at #318: G45 G 554351_85_257 at #321: P46 554351_85_257 at #321: P46 P 554351_85_257 at #322: Y47 554351_85_257 at #322: Y47 Y 554351_85_257 at #324: K48 554351_85_257 at #324: K48 K 554351_85_257 at #326: N49 554351_85_257 at #326: N49 N 554351_85_257 at #327: F50 554351_85_257 at #327: F50 F 554351_85_257 at #328: R51 554351_85_257 at #328: R51 R 554351_85_257 at #329: Y52 554351_85_257 at #329: Y52 Y 554351_85_257 at #330: R53 554351_85_257 at #330: R53 R 554351_85_257 at #331: A54 554351_85_257 at #331: A54 A 554351_85_257 at #332: E55 554351_85_257 at #332: E55 E 554351_85_257 at #333: V56 554351_85_257 at #333: V56 V 554351_85_257 at #334: K57 554351_85_257 at #334: K57 K 554351_85_257 at #335: I58 554351_85_257 at #335: I58 I 554351_85_257 at #351: N59 554351_85_257 at #351: N59 N 554351_85_257 at #352: D60 554351_85_257 at #352: D60 D 554351_85_257 at #354: G61 554351_85_257 at #354: G61 G 554351_85_257 at #355: G62 554351_85_257 at #355: G62 G 554351_85_257 at #385: N63 554351_85_257 at #385: N63 N 554351_85_257 at #386: S64 554351_85_257 at #386: S64 S 554351_85_257 at #387: G65 554351_85_257 at #387: G65 G 554351_85_257 at #388: V66 554351_85_257 at #388: V66 V 554351_85_257 at #389: Y67 554351_85_257 at #389: Y67 Y 554351_85_257 at #390: F68 554351_85_257 at #390: F68 F 554351_85_257 at #391: R69 554351_85_257 at #391: R69 R 554351_85_257 at #392: T70 554351_85_257 at #392: T70 T 554351_85_257 at #393: T71 554351_85_257 at #393: T71 T 554351_85_257 at #423 554351_85_257 at #423 - 554351_85_257 at #424 554351_85_257 at #424 - 554351_85_257 at #425: R72 554351_85_257 at #425: R72 R 554351_85_257 at #426: K73 554351_85_257 at #426: K73 K 554351_85_257 at #430: P74 554351_85_257 at #430: P74 P 554351_85_257 at #431: G75 554351_85_257 at #431: G75 G 554351_85_257 at #432: F76 554351_85_257 at #432: F76 F 554351_85_257 at #433: M77 554351_85_257 at #433: M77 M 554351_85_257 at #434: D78 554351_85_257 at #434: D78 D 554351_85_257 at #435: G79 554351_85_257 at #435: G79 G 554351_85_257 at #436: Y80 554351_85_257 at #436: Y80 Y 554351_85_257 at #438: E81 554351_85_257 at #438: E81 E 554351_85_257 at #439: A82 554351_85_257 at #439: A82 A 554351_85_257 at #440: Q83 554351_85_257 at #440: Q83 Q 554351_85_257 at #441: V84 554351_85_257 at #441: V84 V 554351_85_257 at #442: D85 554351_85_257 at #442: D85 D 554351_85_257 at #443: S86 554351_85_257 at #443: S86 S 554351_85_257 at #450: T87 554351_85_257 at #450: T87 T 554351_85_257 at #451: H88 554351_85_257 at #451: H88 H 554351_85_257 at #452: T89 554351_85_257 at #452: T89 T 554351_85_257 at #453: D90 554351_85_257 at #453: D90 D 554351_85_257 at #475 554351_85_257 at #475 - 554351_85_257 at #476 554351_85_257 at #476 - 554351_85_257 at #477 554351_85_257 at #477 - 554351_85_257 at #478: P91 554351_85_257 at #478: P91 P 554351_85_257 at #479: I92 554351_85_257 at #479: I92 I 554351_85_257 at #480: R93 554351_85_257 at #480: R93 R 554351_85_257 at #481: T94 554351_85_257 at #481: T94 T 554351_85_257 at #482: G95 554351_85_257 at #482: G95 G 554351_85_257 at #483: S96 554351_85_257 at #483: S96 S 554351_85_257 at #484: L97 554351_85_257 at #484: L97 L 554351_85_257 at #485: Y98 554351_85_257 at #485: Y98 Y 554351_85_257 at #486 554351_85_257 at #486 - 554351_85_257 at #487 554351_85_257 at #487 - 554351_85_257 at #530 554351_85_257 at #530 - 554351_85_257 at #532 554351_85_257 at #532 - 554351_85_257 at #533: G99 554351_85_257 at #533: G99 G 554351_85_257 at #534: F100 554351_85_257 at #534: F100 F 554351_85_257 at #535: C101 554351_85_257 at #535: C101 C 554351_85_257 at #544: H102 554351_85_257 at #544: H102 H 554351_85_257 at #545: V103 554351_85_257 at #545: V103 V 554351_85_257 at #548: Y104 554351_85_257 at #548: Y104 Y 554351_85_257 at #549: P105 554351_85_257 at #549: P105 P 554351_85_257 at #550: Q106 554351_85_257 at #550: Q106 Q 554351_85_257 at #551: L107 554351_85_257 at #551: L107 L 554351_85_257 at #552: V108 554351_85_257 at #552: V108 V 554351_85_257 at #553: K109 554351_85_257 at #553: K109 K 554351_85_257 at #554: P110 554351_85_257 at #554: P110 P 554351_85_257 at #555: D111 554351_85_257 at #555: D111 D 554351_85_257 at #556: T112 554351_85_257 at #556: T112 T 554351_85_257 at #557: W113 554351_85_257 at #557: W113 W 554351_85_257 at #558: F114 554351_85_257 at #558: F114 F 554351_85_257 at #559: T115 554351_85_257 at #559: T115 T 554351_85_257 at #560: Y116 554351_85_257 at #560: Y116 Y 554351_85_257 at #561: E117 554351_85_257 at #561: E117 E 554351_85_257 at #562: I118 554351_85_257 at #562: I118 I 554351_85_257 at #565: E119 554351_85_257 at #565: E119 E 554351_85_257 at #566: V120 554351_85_257 at #566: V120 V 554351_85_257 at #568: K121 554351_85_257 at #568: K121 K 554351_85_257 at #570: D122 554351_85_257 at #570: D122 D 554351_85_257 at #571: D123 554351_85_257 at #571: D123 D 554351_85_257 at #572: N124 554351_85_257 at #572: N124 N 554351_85_257 at #588: I133 554351_85_257 at #588: I133 I 554351_85_257 at #589: K134 554351_85_257 at #589: K134 K 554351_85_257 at #592: I135 554351_85_257 at #592: I135 I 554351_85_257 at #594: T136 554351_85_257 at #594: T136 T 554351_85_257 at #595: V137 554351_85_257 at #595: V137 V 554351_85_257 at #596: D138 554351_85_257 at #596: D138 D 554351_85_257 at #598: G139 554351_85_257 at #598: G139 G 554351_85_257 at #599: N140 554351_85_257 at #599: N140 N 554351_85_257 at #600: E141 554351_85_257 at #600: E141 E 554351_85_257 at #601: L142 554351_85_257 at #601: L142 L 554351_85_257 at #602: Y143 554351_85_257 at #602: Y143 Y 554351_85_257 at #603: E144 554351_85_257 at #603: E144 E 554351_85_257 at #604: Y145 554351_85_257 at #604: Y145 Y 554351_85_257 at #605: M146 554351_85_257 at #605: M146 M 554351_85_257 at #606: D147 554351_85_257 at #606: D147 D 554351_85_257 at #607: F148 554351_85_257 at #607: F148 F 554351_85_257 at #608: E149 554351_85_257 at #608: E149 E 554351_85_257 at #609: K150 554351_85_257 at #609: K150 K 554351_85_257 at #610: T151 554351_85_257 at #610: T151 T 554351_85_257 at #611: Y152 554351_85_257 at #611: Y152 Y 554351_85_257 at #612 554351_85_257 at #612 - 554351_85_257 at #613 554351_85_257 at #613 - 554351_85_257 at #614 554351_85_257 at #614 - 554351_85_257 at #615 554351_85_257 at #615 - 554351_85_257 at #616 554351_85_257 at #616 - 554351_85_257 at #640 554351_85_257 at #640 - 554351_85_257 at #641 554351_85_257 at #641 - 554351_85_257 at #642 554351_85_257 at #642 - 554351_85_257 at #643: G153 554351_85_257 at #643: G153 G 554351_85_257 at #644: P154 554351_85_257 at #644: P154 P 554351_85_257 at #645: G155 554351_85_257 at #645: G155 G 554351_85_257 at #646: H156 554351_85_257 at #646: H156 H 554351_85_257 at #647: F157 554351_85_257 at #647: F157 F 554351_85_257 at #648: A158 554351_85_257 at #648: A158 A 554351_85_257 at #649: F159 554351_85_257 at #649: F159 F 554351_85_257 at #650: Q160 554351_85_257 at #650: Q160 Q 554351_85_257 at #653: Q161 554351_85_257 at #653: Q161 Q 554351_85_257 at #654: H162 554351_85_257 at #654: H162 H 554351_85_257 at #655: D163 554351_85_257 at #655: D163 D 554351_85_257 at #668: P164 554351_85_257 at #668: P164 P 554351_85_257 at #689 554351_85_257 at #689 - 554351_85_257 at #690 554351_85_257 at #690 - 554351_85_257 at #691 554351_85_257 at #691 - 554351_85_257 at #694 554351_85_257 at #694 - 554351_85_257 at #695 554351_85_257 at #695 - 554351_85_257 at #696 554351_85_257 at #696 - 554351_85_257 at #697 554351_85_257 at #697 - 554351_85_257 at #698 554351_85_257 at #698 - 554351_85_257 at #699 554351_85_257 at #699 - 554351_85_257 at #700 554351_85_257 at #700 - single domain, from Isosphaera pallida IS1B, ATCC 43644 11269824_44_215 single domain, from Isosphaera pallida IS1B, ATCC 43644 11269824_44_215 at #155: E1 11269824_44_215 at #155: E1 E 11269824_44_215 at #156: W2 11269824_44_215 at #156: W2 W 11269824_44_215 at #157: V3 11269824_44_215 at #157: V3 V 11269824_44_215 at #158: A4 11269824_44_215 at #158: A4 A 11269824_44_215 at #159: L5 11269824_44_215 at #159: L5 L 11269824_44_215 at #160: F6 11269824_44_215 at #160: F6 F 11269824_44_215 at #162: D7 11269824_44_215 at #162: D7 D 11269824_44_215 at #164: G8 11269824_44_215 at #164: G8 G 11269824_44_215 at #165: Q9 11269824_44_215 at #165: Q9 Q 11269824_44_215 at #168: T10 11269824_44_215 at #168: T10 T 11269824_44_215 at #169: L11 11269824_44_215 at #169: L11 L 11269824_44_215 at #171: Q12 11269824_44_215 at #171: Q12 Q 11269824_44_215 at #172: G13 11269824_44_215 at #172: G13 G 11269824_44_215 at #180: W14 11269824_44_215 at #180: W14 W 11269824_44_215 at #181: E15 11269824_44_215 at #181: E15 E 11269824_44_215 at #185: S16 11269824_44_215 at #185: S16 S 11269824_44_215 at #186: W17 11269824_44_215 at #186: W17 W 11269824_44_215 at #187: D18 11269824_44_215 at #187: D18 D 11269824_44_215 at #188: A19 11269824_44_215 at #188: A19 A 11269824_44_215 at #189: K20 11269824_44_215 at #189: K20 K 11269824_44_215 at #190: G21 11269824_44_215 at #190: G21 G 11269824_44_215 at #191: K22 11269824_44_215 at #191: K22 K 11269824_44_215 at #195: A26 11269824_44_215 at #195: A26 A 11269824_44_215 at #196: K27 11269824_44_215 at #196: K27 K 11269824_44_215 at #197: N28 11269824_44_215 at #197: N28 N 11269824_44_215 at #198: W29 11269824_44_215 at #198: W29 W 11269824_44_215 at #235: K30 11269824_44_215 at #235: K30 K 11269824_44_215 at #236: V31 11269824_44_215 at #236: V31 V 11269824_44_215 at #237: E32 11269824_44_215 at #237: E32 E 11269824_44_215 at #238: E33 11269824_44_215 at #238: E33 E 11269824_44_215 at #240: G34 11269824_44_215 at #240: G34 G 11269824_44_215 at #268: A35 11269824_44_215 at #268: A35 A 11269824_44_215 at #269: I36 11269824_44_215 at #269: I36 I 11269824_44_215 at #270: H37 11269824_44_215 at #270: H37 H 11269824_44_215 at #294 11269824_44_215 at #294 - 11269824_44_215 at #295 11269824_44_215 at #295 - 11269824_44_215 at #296: G38 11269824_44_215 at #296: G38 G 11269824_44_215 at #297: F39 11269824_44_215 at #297: F39 F 11269824_44_215 at #298: G40 11269824_44_215 at #298: G40 G 11269824_44_215 at #299: E41 11269824_44_215 at #299: E41 E 11269824_44_215 at #300: V42 11269824_44_215 at #300: V42 V 11269824_44_215 at #301: A43 11269824_44_215 at #301: A43 A 11269824_44_215 at #303: H44 11269824_44_215 at #303: H44 H 11269824_44_215 at #304: L45 11269824_44_215 at #304: L45 L 11269824_44_215 at #305: F46 11269824_44_215 at #305: F46 F 11269824_44_215 at #306: S47 11269824_44_215 at #306: S47 S 11269824_44_215 at #312: E48 11269824_44_215 at #312: E48 E 11269824_44_215 at #318: R49 11269824_44_215 at #318: R49 R 11269824_44_215 at #321: D51 11269824_44_215 at #321: D51 D 11269824_44_215 at #322: Y52 11269824_44_215 at #322: Y52 Y 11269824_44_215 at #324: E53 11269824_44_215 at #324: E53 E 11269824_44_215 at #326: N54 11269824_44_215 at #326: N54 N 11269824_44_215 at #327: F55 11269824_44_215 at #327: F55 F 11269824_44_215 at #328: H56 11269824_44_215 at #328: H56 H 11269824_44_215 at #329: L57 11269824_44_215 at #329: L57 L 11269824_44_215 at #330: R58 11269824_44_215 at #330: R58 R 11269824_44_215 at #331: A59 11269824_44_215 at #331: A59 A 11269824_44_215 at #332: E60 11269824_44_215 at #332: E60 E 11269824_44_215 at #333: I61 11269824_44_215 at #333: I61 I 11269824_44_215 at #334: K62 11269824_44_215 at #334: K62 K 11269824_44_215 at #335: I63 11269824_44_215 at #335: I63 I 11269824_44_215 at #351: A64 11269824_44_215 at #351: A64 A 11269824_44_215 at #352: D65 11269824_44_215 at #352: D65 D 11269824_44_215 at #354: K66 11269824_44_215 at #354: K66 K 11269824_44_215 at #355: G67 11269824_44_215 at #355: G67 G 11269824_44_215 at #385: N68 11269824_44_215 at #385: N68 N 11269824_44_215 at #386: S69 11269824_44_215 at #386: S69 S 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11269824_44_215 at #698: E171 E 11269824_44_215 at #699: I172 11269824_44_215 at #699: I172 I 11269824_44_215 at #700 11269824_44_215 at #700 - download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory