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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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Highlight proteins:

0.974 6253341_25_206: single domain, from Chthoniobacter flavus Ellin428 0.905 2764129_27_207: single domain, from Blastopirellula marina DSM 3645 6004371_23_210: single domain, from Verrucomicrobium spinosum DSM 4136 0.5 /site single domain, from Chthoniobacter flavus Ellin428 6253341_25_206 single domain, from Chthoniobacter flavus Ellin428 single domain, from Blastopirellula marina DSM 3645 2764129_27_207 single domain, from Blastopirellula marina DSM 3645 single domain, from Verrucomicrobium spinosum DSM 4136 6004371_23_210 single domain, from Verrucomicrobium spinosum DSM 4136 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory