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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.974 3722502_28_193: with other domain, from Parabacteroides distasonis ATCC 8503 4262859_41_193: with other domain, from Bacteroides uniformis ATCC 8492 0.5 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 with other domain, from Parabacteroides distasonis ATCC 8503 3722502_28_193 with other domain, from Parabacteroides distasonis ATCC 8503 3722502_28_193 at #155 3722502_28_193 at #155 - 3722502_28_193 at #156 3722502_28_193 at #156 - 3722502_28_193 at #157 3722502_28_193 at #157 - 3722502_28_193 at #158 3722502_28_193 at #158 - 3722502_28_193 at #159 3722502_28_193 at #159 - 3722502_28_193 at #160 3722502_28_193 at #160 - 3722502_28_193 at #162 3722502_28_193 at #162 - 3722502_28_193 at #164 3722502_28_193 at #164 - 3722502_28_193 at #165 3722502_28_193 at #165 - 3722502_28_193 at #168 3722502_28_193 at #168 - 3722502_28_193 at #169 3722502_28_193 at #169 - 3722502_28_193 at #171: N4 3722502_28_193 at #171: N4 N 3722502_28_193 at #172: A5 3722502_28_193 at #172: A5 A 3722502_28_193 at #180: W6 3722502_28_193 at #180: W6 W 3722502_28_193 at #181: K7 3722502_28_193 at #181: K7 K 3722502_28_193 at #185: T8 3722502_28_193 at #185: T8 T 3722502_28_193 at #186: T9 3722502_28_193 at #186: T9 T 3722502_28_193 at #187 3722502_28_193 at #187 - 3722502_28_193 at #188 3722502_28_193 at #188 - 3722502_28_193 at #189 3722502_28_193 at #189 - 3722502_28_193 at #190 3722502_28_193 at #190 - 3722502_28_193 at #191 3722502_28_193 at #191 - 3722502_28_193 at #195 3722502_28_193 at #195 - 3722502_28_193 at #196: G10 3722502_28_193 at #196: G10 G 3722502_28_193 at #197: V11 3722502_28_193 at #197: V11 V 3722502_28_193 at #198: V12 3722502_28_193 at #198: V12 V 3722502_28_193 at #235: V13 3722502_28_193 at #235: V13 V 3722502_28_193 at #236: I14 3722502_28_193 at #236: I14 I 3722502_28_193 at #237: Q15 3722502_28_193 at #237: Q15 Q 3722502_28_193 at #238: N16 3722502_28_193 at #238: N16 N 3722502_28_193 at #240: D17 3722502_28_193 at #240: D17 D 3722502_28_193 at #268: V18 3722502_28_193 at #268: V18 V 3722502_28_193 at #269: L19 3722502_28_193 at #269: L19 L 3722502_28_193 at #270: T20 3722502_28_193 at #270: T20 T 3722502_28_193 at #294 3722502_28_193 at #294 - 3722502_28_193 at #295: L21 3722502_28_193 at #295: L21 L 3722502_28_193 at #296: A22 3722502_28_193 at #296: A22 A 3722502_28_193 at #297: G23 3722502_28_193 at #297: G23 G 3722502_28_193 at #298: S24 3722502_28_193 at #298: S24 S 3722502_28_193 at #299: N25 3722502_28_193 at #299: N25 N 3722502_28_193 at #300: A26 3722502_28_193 at #300: A26 A 3722502_28_193 at #301: R27 3722502_28_193 at #301: R27 R 3722502_28_193 at #303: A28 3722502_28_193 at #303: A28 A 3722502_28_193 at #304: L29 3722502_28_193 at #304: L29 L 3722502_28_193 at #305: L30 3722502_28_193 at #305: L30 L 3722502_28_193 at #306: N31 3722502_28_193 at #306: N31 N 3722502_28_193 at #312: D32 3722502_28_193 at #312: D32 D 3722502_28_193 at #318: K34 3722502_28_193 at #318: K34 K 3722502_28_193 at #321: G35 3722502_28_193 at #321: G35 G 3722502_28_193 at #322: Y36 3722502_28_193 at #322: Y36 Y 3722502_28_193 at #324: T37 3722502_28_193 at #324: T37 T 3722502_28_193 at #326: N38 3722502_28_193 at #326: N38 N 3722502_28_193 at #327: F39 3722502_28_193 at #327: F39 F 3722502_28_193 at #328: E40 3722502_28_193 at #328: E40 E 3722502_28_193 at #329: L41 3722502_28_193 at #329: L41 L 3722502_28_193 at #330: D42 3722502_28_193 at #330: D42 D 3722502_28_193 at #331: M43 3722502_28_193 at #331: M43 M 3722502_28_193 at #332: D44 3722502_28_193 at #332: D44 D 3722502_28_193 at #333: V45 3722502_28_193 at #333: V45 V 3722502_28_193 at #334: R46 3722502_28_193 at #334: R46 R 3722502_28_193 at #335: T47 3722502_28_193 at #335: T47 T 3722502_28_193 at #351: T48 3722502_28_193 at #351: T48 T 3722502_28_193 at #352: T49 3722502_28_193 at #352: T49 T 3722502_28_193 at #354: G50 3722502_28_193 at #354: G50 G 3722502_28_193 at #355: G51 3722502_28_193 at #355: G51 G 3722502_28_193 at #385: K52 3722502_28_193 at #385: K52 K 3722502_28_193 at #386: G53 3722502_28_193 at #386: G53 G 3722502_28_193 at #387: Y54 3722502_28_193 at #387: Y54 Y 3722502_28_193 at #388: I55 3722502_28_193 at #388: I55 I 3722502_28_193 at #389: G56 3722502_28_193 at #389: G56 G 3722502_28_193 at #390: I57 3722502_28_193 at #390: I57 I 3722502_28_193 at #391: H58 3722502_28_193 at #391: H58 H 3722502_28_193 at #392: T59 3722502_28_193 at #392: T59 T 3722502_28_193 at #393: D60 3722502_28_193 at #393: D60 D 3722502_28_193 at #423 3722502_28_193 at #423 - 3722502_28_193 at #424 3722502_28_193 at #424 - 3722502_28_193 at #425 3722502_28_193 at #425 - 3722502_28_193 at #426 3722502_28_193 at #426 - 3722502_28_193 at #430: A61 3722502_28_193 at #430: A61 A 3722502_28_193 at #431: T62 3722502_28_193 at #431: T62 T 3722502_28_193 at #432: D63 3722502_28_193 at #432: D63 D 3722502_28_193 at #433: R64 3722502_28_193 at #433: R64 R 3722502_28_193 at #434: K65 3722502_28_193 at #434: K65 K 3722502_28_193 at #435: G66 3722502_28_193 at #435: G66 G 3722502_28_193 at #436: Y67 3722502_28_193 at #436: Y67 Y 3722502_28_193 at #438: R68 3722502_28_193 at #438: R68 R 3722502_28_193 at #439: I69 3722502_28_193 at #439: I69 I 3722502_28_193 at #440: A70 3722502_28_193 at #440: A70 A 3722502_28_193 at #441: L71 3722502_28_193 at #441: L71 L 3722502_28_193 at #442: N72 3722502_28_193 at #442: N72 N 3722502_28_193 at #443: N73 3722502_28_193 at #443: N73 N 3722502_28_193 at #450: D74 3722502_28_193 at #450: D74 D 3722502_28_193 at #451: R75 3722502_28_193 at #451: R75 R 3722502_28_193 at #452: E76 3722502_28_193 at #452: E76 E 3722502_28_193 at #453: D77 3722502_28_193 at #453: D77 D 3722502_28_193 at #475: P78 3722502_28_193 at #475: P78 P 3722502_28_193 at #476: V79 3722502_28_193 at #476: V79 V 3722502_28_193 at #477: W80 3722502_28_193 at #477: W80 W 3722502_28_193 at #478: W81 3722502_28_193 at #478: W81 W 3722502_28_193 at #479: R82 3722502_28_193 at #479: R82 R 3722502_28_193 at #480: M83 3722502_28_193 at #480: M83 M 3722502_28_193 at #481: T84 3722502_28_193 at #481: T84 T 3722502_28_193 at #482: G85 3722502_28_193 at #482: G85 G 3722502_28_193 at #483: S86 3722502_28_193 at #483: S86 S 3722502_28_193 at #484: L87 3722502_28_193 at #484: L87 L 3722502_28_193 at #485: V88 3722502_28_193 at #485: V88 V 3722502_28_193 at #486 3722502_28_193 at #486 - 3722502_28_193 at #487 3722502_28_193 at #487 - 3722502_28_193 at #530 3722502_28_193 at #530 - 3722502_28_193 at #532 3722502_28_193 at #532 - 3722502_28_193 at #533: S89 3722502_28_193 at #533: S89 S 3722502_28_193 at #534: V90 3722502_28_193 at #534: V90 V 3722502_28_193 at #535: R91 3722502_28_193 at #535: R91 R 3722502_28_193 at #544: N92 3722502_28_193 at #544: N92 N 3722502_28_193 at #545: L93 3722502_28_193 at #545: L93 L 3722502_28_193 at #548: T94 3722502_28_193 at #548: T94 T 3722502_28_193 at #549: K95 3722502_28_193 at #549: K95 K 3722502_28_193 at #550: S96 3722502_28_193 at #550: S96 S 3722502_28_193 at #551: F97 3722502_28_193 at #551: F97 F 3722502_28_193 at #552: V98 3722502_28_193 at #552: V98 V 3722502_28_193 at #553: K99 3722502_28_193 at #553: K99 K 3722502_28_193 at #554: E100 3722502_28_193 at #554: E100 E 3722502_28_193 at #555: N101 3722502_28_193 at #555: N101 N 3722502_28_193 at #556: E102 3722502_28_193 at #556: E102 E 3722502_28_193 at #557: W103 3722502_28_193 at #557: W103 W 3722502_28_193 at #558: F104 3722502_28_193 at #558: F104 F 3722502_28_193 at #559: K105 3722502_28_193 at #559: K105 K 3722502_28_193 at #560: M106 3722502_28_193 at #560: M106 M 3722502_28_193 at #561: N107 3722502_28_193 at #561: N107 N 3722502_28_193 at #562: I108 3722502_28_193 at #562: I108 I 3722502_28_193 at #565: R109 3722502_28_193 at #565: R109 R 3722502_28_193 at #566: V110 3722502_28_193 at #566: V110 V 3722502_28_193 at #568: E111 3722502_28_193 at #568: E111 E 3722502_28_193 at #570: G112 3722502_28_193 at #570: G112 G 3722502_28_193 at #571: R113 3722502_28_193 at #571: R113 R 3722502_28_193 at #572: L114 3722502_28_193 at #572: L114 L 3722502_28_193 at #588: I115 3722502_28_193 at #588: I115 I 3722502_28_193 at #589: R116 3722502_28_193 at #589: R116 R 3722502_28_193 at #592: V117 3722502_28_193 at #592: V117 V 3722502_28_193 at #594: R118 3722502_28_193 at #594: R118 R 3722502_28_193 at #595: I119 3722502_28_193 at #595: I119 I 3722502_28_193 at #596: N120 3722502_28_193 at #596: N120 N 3722502_28_193 at #598: G121 3722502_28_193 at #598: G121 G 3722502_28_193 at #599: E122 3722502_28_193 at #599: E122 E 3722502_28_193 at #600: T123 3722502_28_193 at #600: T123 T 3722502_28_193 at #601: V124 3722502_28_193 at #601: V124 V 3722502_28_193 at #602: V125 3722502_28_193 at #602: V125 V 3722502_28_193 at #603: E126 3722502_28_193 at #603: E126 E 3722502_28_193 at #604: Y127 3722502_28_193 at #604: Y127 Y 3722502_28_193 at #605: I128 3722502_28_193 at #605: I128 I 3722502_28_193 at #606: E129 3722502_28_193 at #606: E129 E 3722502_28_193 at #607: P130 3722502_28_193 at #607: P130 P 3722502_28_193 at #608: S131 3722502_28_193 at #608: S131 S 3722502_28_193 at #609: K132 3722502_28_193 at #609: K132 K 3722502_28_193 at #610: P133 3722502_28_193 at #610: P133 P 3722502_28_193 at #611: F134 3722502_28_193 at #611: F134 F 3722502_28_193 at #612: R135 3722502_28_193 at #612: R135 R 3722502_28_193 at #613: L136 3722502_28_193 at #613: L136 L 3722502_28_193 at #614: K137 3722502_28_193 at #614: K137 K 3722502_28_193 at #615: E138 3722502_28_193 at #615: E138 E 3722502_28_193 at #616: N139 3722502_28_193 at #616: N139 N 3722502_28_193 at #640: A142 3722502_28_193 at #640: A142 A 3722502_28_193 at #641: L143 3722502_28_193 at #641: L143 L 3722502_28_193 at #642: L144 3722502_28_193 at #642: L144 L 3722502_28_193 at #643: S145 3722502_28_193 at #643: S145 S 3722502_28_193 at #644: Q146 3722502_28_193 at #644: Q146 Q 3722502_28_193 at #645: G147 3722502_28_193 at #645: G147 G 3722502_28_193 at #646: T148 3722502_28_193 at #646: T148 T 3722502_28_193 at #647: I149 3722502_28_193 at #647: I149 I 3722502_28_193 at #648: S150 3722502_28_193 at #648: S150 S 3722502_28_193 at #649: L151 3722502_28_193 at #649: L151 L 3722502_28_193 at #650: V152 3722502_28_193 at #650: V152 V 3722502_28_193 at #653: G153 3722502_28_193 at #653: G153 G 3722502_28_193 at #654: T154 3722502_28_193 at #654: T154 T 3722502_28_193 at #655: G155 3722502_28_193 at #655: G155 G 3722502_28_193 at #668: G157 3722502_28_193 at #668: G157 G 3722502_28_193 at #689: N158 3722502_28_193 at #689: N158 N 3722502_28_193 at #690: L159 3722502_28_193 at #690: L159 L 3722502_28_193 at #691: Q160 3722502_28_193 at #691: Q160 Q 3722502_28_193 at #694: F161 3722502_28_193 at #694: F161 F 3722502_28_193 at #695: K162 3722502_28_193 at #695: K162 K 3722502_28_193 at #696: N163 3722502_28_193 at #696: N163 N 3722502_28_193 at #697: I164 3722502_28_193 at #697: I164 I 3722502_28_193 at #698: S165 3722502_28_193 at #698: S165 S 3722502_28_193 at #699 3722502_28_193 at #699 - 3722502_28_193 at #700 3722502_28_193 at #700 - with other domain, from Bacteroides uniformis ATCC 8492 4262859_41_193 with other domain, from Bacteroides uniformis ATCC 8492 4262859_41_193 at #155 4262859_41_193 at #155 - 4262859_41_193 at #156 4262859_41_193 at #156 - 4262859_41_193 at #157 4262859_41_193 at #157 - 4262859_41_193 at #158 4262859_41_193 at #158 - 4262859_41_193 at #159 4262859_41_193 at #159 - 4262859_41_193 at #160 4262859_41_193 at #160 - 4262859_41_193 at #162 4262859_41_193 at #162 - 4262859_41_193 at #164 4262859_41_193 at #164 - 4262859_41_193 at #165 4262859_41_193 at #165 - 4262859_41_193 at #168 4262859_41_193 at #168 - 4262859_41_193 at #169 4262859_41_193 at #169 - 4262859_41_193 at #171 4262859_41_193 at #171 - 4262859_41_193 at #172 4262859_41_193 at #172 - 4262859_41_193 at #180 4262859_41_193 at #180 - 4262859_41_193 at #181 4262859_41_193 at #181 - 4262859_41_193 at #185 4262859_41_193 at #185 - 4262859_41_193 at #186 4262859_41_193 at #186 - 4262859_41_193 at #187 4262859_41_193 at #187 - 4262859_41_193 at #188 4262859_41_193 at #188 - 4262859_41_193 at #189 4262859_41_193 at #189 - 4262859_41_193 at #190 4262859_41_193 at #190 - 4262859_41_193 at #191 4262859_41_193 at #191 - 4262859_41_193 at #195 4262859_41_193 at #195 - 4262859_41_193 at #196 4262859_41_193 at #196 - 4262859_41_193 at #197 4262859_41_193 at #197 - 4262859_41_193 at #198 4262859_41_193 at #198 - 4262859_41_193 at #235 4262859_41_193 at #235 - 4262859_41_193 at #236 4262859_41_193 at #236 - 4262859_41_193 at #237 4262859_41_193 at #237 - 4262859_41_193 at #238: D4 4262859_41_193 at #238: D4 D 4262859_41_193 at #240: G5 4262859_41_193 at #240: G5 G 4262859_41_193 at #268: T6 4262859_41_193 at #268: T6 T 4262859_41_193 at #269: S7 4262859_41_193 at #269: S7 S 4262859_41_193 at #270: T8 4262859_41_193 at #270: T8 T 4262859_41_193 at #294: D13 4262859_41_193 at #294: D13 D 4262859_41_193 at #295: P14 4262859_41_193 at #295: P14 P 4262859_41_193 at #296: V15 4262859_41_193 at #296: V15 V 4262859_41_193 at #297: I16 4262859_41_193 at #297: I16 I 4262859_41_193 at #298: A17 4262859_41_193 at #298: A17 A 4262859_41_193 at #299: E18 4262859_41_193 at #299: E18 E 4262859_41_193 at #300: G19 4262859_41_193 at #300: G19 G 4262859_41_193 at #301: R20 4262859_41_193 at #301: R20 R 4262859_41_193 at #303: K21 4262859_41_193 at #303: K21 K 4262859_41_193 at #304: L22 4262859_41_193 at #304: L22 L 4262859_41_193 at #305: F23 4262859_41_193 at #305: F23 F 4262859_41_193 at #306: N24 4262859_41_193 at #306: N24 N 4262859_41_193 at #312: D25 4262859_41_193 at #312: D25 D 4262859_41_193 at #318: K26 4262859_41_193 at #318: K26 K 4262859_41_193 at #321: E27 4262859_41_193 at #321: E27 E 4262859_41_193 at #322: Y28 4262859_41_193 at #322: Y28 Y 4262859_41_193 at #324: Q29 4262859_41_193 at #324: Q29 Q 4262859_41_193 at #326: N30 4262859_41_193 at #326: N30 N 4262859_41_193 at #327: F31 4262859_41_193 at #327: F31 F 4262859_41_193 at #328: R32 4262859_41_193 at #328: R32 R 4262859_41_193 at #329: L33 4262859_41_193 at #329: L33 L 4262859_41_193 at #330: T34 4262859_41_193 at #330: T34 T 4262859_41_193 at #331: G35 4262859_41_193 at #331: G35 G 4262859_41_193 at #332: E36 4262859_41_193 at #332: E36 E 4262859_41_193 at #333: A37 4262859_41_193 at #333: A37 A 4262859_41_193 at #334: L38 4262859_41_193 at #334: L38 L 4262859_41_193 at #335: T39 4262859_41_193 at #335: T39 T 4262859_41_193 at #351: Q40 4262859_41_193 at #351: Q40 Q 4262859_41_193 at #352: P41 4262859_41_193 at #352: P41 P 4262859_41_193 at #354: G42 4262859_41_193 at #354: G42 G 4262859_41_193 at #355: S43 4262859_41_193 at #355: S43 S 4262859_41_193 at #385: E44 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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory