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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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Highlight proteins:

0.927 0.970 11294790_78_245: tandem domain, from Planctomyces brasiliensis DSM 5305 0.823 558057_88_251: tandem domain, from Pirellula sp. 1 0.829 10357232_410_572: with other domain, from Coraliomargarita akajimensis DSM 45221 0.324 4595334_71_236: tandem domain, from Planctomyces maris DSM 8797 0.125 2760313_39_201: tandem domain, from Blastopirellula marina DSM 3645 10307912_189_353: tandem domain, from Pirellula staleyi DSM 6068 0.968 2767479_46_191: single domain, from Flavobacteriales bacterium HTCC2170 0.813 6890070_31_195: single domain, from Polynucleobacter sp. QLW-P1DMWA-1 10343720_38_183: single domain, from Allochromatium vinosum DSM 180 1 /site tandem domain, from Planctomyces brasiliensis DSM 5305 11294790_78_245 tandem domain, from Planctomyces brasiliensis DSM 5305 tandem domain, from Pirellula sp. 1 558057_88_251 tandem domain, from Pirellula sp. 1 with other domain, from Coraliomargarita akajimensis DSM 45221 10357232_410_572 with other domain, from Coraliomargarita akajimensis DSM 45221 tandem domain, from Planctomyces maris DSM 8797 4595334_71_236 tandem domain, from Planctomyces maris DSM 8797 tandem domain, from Blastopirellula marina DSM 3645 2760313_39_201 tandem domain, from Blastopirellula marina DSM 3645 tandem domain, from Pirellula staleyi DSM 6068 10307912_189_353 tandem domain, from Pirellula staleyi DSM 6068 single domain, from Flavobacteriales bacterium HTCC2170 2767479_46_191 single domain, from Flavobacteriales bacterium HTCC2170 single domain, from Polynucleobacter sp. QLW-P1DMWA-1 6890070_31_195 single domain, from Polynucleobacter sp. QLW-P1DMWA-1 single domain, from Allochromatium vinosum DSM 180 10343720_38_183 single domain, from Allochromatium vinosum DSM 180 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory