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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.932 0.920 6004792_562_779: with other domain, from Verrucomicrobium spinosum DSM 4136 0.893 7352115_10_283: single domain, near sugar dehydrogenase, from Arthrobacter chlorophenolicus A6 10307627_52_286: single domain, from Pirellula staleyi DSM 6068 11129631_48_250: single domain, from Aquiflexum balticum BA160, DSM 16537 1 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 with other domain, from Verrucomicrobium spinosum DSM 4136 6004792_562_779 with other domain, from Verrucomicrobium spinosum DSM 4136 6004792_562_779 at #155: G1 6004792_562_779 at #155: G1 G 6004792_562_779 at #156: F2 6004792_562_779 at #156: F2 F 6004792_562_779 at #157: I3 6004792_562_779 at #157: I3 I 6004792_562_779 at #158: S4 6004792_562_779 at #158: S4 S 6004792_562_779 at #159: L5 6004792_562_779 at #159: L5 L 6004792_562_779 at #160: F6 6004792_562_779 at #160: F6 F 6004792_562_779 at #162: D7 6004792_562_779 at #162: D7 D 6004792_562_779 at #164: G8 6004792_562_779 at #164: G8 G 6004792_562_779 at #165: K9 6004792_562_779 at #165: K9 K 6004792_562_779 at #168: T10 6004792_562_779 at #168: T10 T 6004792_562_779 at #169: L11 6004792_562_779 at #169: L11 L 6004792_562_779 at #171: K12 6004792_562_779 at #171: K12 K 6004792_562_779 at #172: G13 6004792_562_779 at #172: G13 G 6004792_562_779 at #180: W14 6004792_562_779 at #180: W14 W 6004792_562_779 at #181: H15 6004792_562_779 at #181: H15 H 6004792_562_779 at #185: V16 6004792_562_779 at #185: V16 V 6004792_562_779 at #186: S17 6004792_562_779 at #186: S17 S 6004792_562_779 at #187: A18 6004792_562_779 at #187: A18 A 6004792_562_779 at #188: K19 6004792_562_779 at #188: K19 K 6004792_562_779 at #189: S20 6004792_562_779 at #189: S20 S 6004792_562_779 at #190: G21 6004792_562_779 at #190: G21 G 6004792_562_779 at #191: H22 6004792_562_779 at #191: H22 H 6004792_562_779 at #195: S23 6004792_562_779 at #195: S23 S 6004792_562_779 at #196: R24 6004792_562_779 at #196: R24 R 6004792_562_779 at #197: T25 6004792_562_779 at #197: T25 T 6004792_562_779 at #198: S26 6004792_562_779 at #198: S26 S 6004792_562_779 at #235: E35 6004792_562_779 at #235: E35 E 6004792_562_779 at #236: V36 6004792_562_779 at #236: V36 V 6004792_562_779 at #237: V37 6004792_562_779 at #237: V37 V 6004792_562_779 at #238: D38 6004792_562_779 at #238: D38 D 6004792_562_779 at #240: G39 6004792_562_779 at #240: G39 G 6004792_562_779 at #268: A40 6004792_562_779 at #268: A40 A 6004792_562_779 at #269: I41 6004792_562_779 at #269: I41 I 6004792_562_779 at #270: T42 6004792_562_779 at #270: T42 T 6004792_562_779 at #294: Q45 6004792_562_779 at #294: Q45 Q 6004792_562_779 at #295: D46 6004792_562_779 at #295: D46 D 6004792_562_779 at #296: V47 6004792_562_779 at #296: V47 V 6004792_562_779 at #297: P48 6004792_562_779 at #297: P48 P 6004792_562_779 at #298: G49 6004792_562_779 at #298: G49 G 6004792_562_779 at #299: N50 6004792_562_779 at #299: N50 N 6004792_562_779 at #300: G51 6004792_562_779 at #300: G51 G 6004792_562_779 at #301: G52 6004792_562_779 at #301: G52 G 6004792_562_779 at #303: L53 6004792_562_779 at #303: L53 L 6004792_562_779 at #304: I54 6004792_562_779 at #304: I54 I 6004792_562_779 at #305: L55 6004792_562_779 at #305: L55 L 6004792_562_779 at #306: T56 6004792_562_779 at #306: T56 T 6004792_562_779 at #312: D57 6004792_562_779 at #312: D57 D 6004792_562_779 at #318: E58 6004792_562_779 at #318: E58 E 6004792_562_779 at #321: K59 6004792_562_779 at #321: K59 K 6004792_562_779 at #322: Y60 6004792_562_779 at #322: Y60 Y 6004792_562_779 at #324: S61 6004792_562_779 at #324: S61 S 6004792_562_779 at #326: Q62 6004792_562_779 at #326: Q62 Q 6004792_562_779 at #327: F63 6004792_562_779 at #327: F63 F 6004792_562_779 at #328: E64 6004792_562_779 at #328: E64 E 6004792_562_779 at #329: V65 6004792_562_779 at #329: V65 V 6004792_562_779 at #330: I66 6004792_562_779 at #330: I66 I 6004792_562_779 at #331: L67 6004792_562_779 at #331: L67 L 6004792_562_779 at #332: E68 6004792_562_779 at #332: E68 E 6004792_562_779 at #333: M69 6004792_562_779 at #333: M69 M 6004792_562_779 at #334: K70 6004792_562_779 at #334: K70 K 6004792_562_779 at #335 6004792_562_779 at #335 - 6004792_562_779 at #351: N71 6004792_562_779 at #351: N71 N 6004792_562_779 at #352: D72 6004792_562_779 at #352: D72 D 6004792_562_779 at #354: F73 6004792_562_779 at #354: F73 F 6004792_562_779 at #355: G74 6004792_562_779 at #355: G74 G 6004792_562_779 at #385: D76 6004792_562_779 at #385: D76 D 6004792_562_779 at #386: S77 6004792_562_779 at #386: S77 S 6004792_562_779 at #387: G78 6004792_562_779 at #387: G78 G 6004792_562_779 at #388: L79 6004792_562_779 at #388: L79 L 6004792_562_779 at #389: F80 6004792_562_779 at #389: F80 F 6004792_562_779 at #390: L81 6004792_562_779 at #390: L81 L 6004792_562_779 at #391: R82 6004792_562_779 at #391: R82 R 6004792_562_779 at #392: S83 6004792_562_779 at #392: S83 S 6004792_562_779 at #393: T84 6004792_562_779 at #393: T84 T 6004792_562_779 at #423 6004792_562_779 at #423 - 6004792_562_779 at #424 6004792_562_779 at #424 - 6004792_562_779 at #425 6004792_562_779 at #425 - 6004792_562_779 at #426 6004792_562_779 at #426 - 6004792_562_779 at #430 6004792_562_779 at #430 - 6004792_562_779 at #431: E85 6004792_562_779 at #431: E85 E 6004792_562_779 at #432: D86 6004792_562_779 at #432: D86 D 6004792_562_779 at #433: G87 6004792_562_779 at #433: G87 G 6004792_562_779 at #434: K88 6004792_562_779 at #434: K88 K 6004792_562_779 at #435: C89 6004792_562_779 at #435: C89 C 6004792_562_779 at #436: Y90 6004792_562_779 at #436: Y90 Y 6004792_562_779 at #438: Q91 6004792_562_779 at #438: Q91 Q 6004792_562_779 at #439: G92 6004792_562_779 at #439: G92 G 6004792_562_779 at #440: L93 6004792_562_779 at #440: L93 L 6004792_562_779 at #441: I94 6004792_562_779 at #441: I94 I 6004792_562_779 at #442: D95 6004792_562_779 at #442: D95 D 6004792_562_779 at #443: F96 6004792_562_779 at #443: F96 F 6004792_562_779 at #450: H97 6004792_562_779 at #450: H97 H 6004792_562_779 at #451: T98 6004792_562_779 at #451: T98 T 6004792_562_779 at #452: G99 6004792_562_779 at #452: G99 G 6004792_562_779 at #453: G100 6004792_562_779 at #453: G100 G 6004792_562_779 at #475 6004792_562_779 at #475 - 6004792_562_779 at #476 6004792_562_779 at #476 - 6004792_562_779 at #477 6004792_562_779 at #477 - 6004792_562_779 at #478 6004792_562_779 at #478 - 6004792_562_779 at #479 6004792_562_779 at #479 - 6004792_562_779 at #480: S101 6004792_562_779 at #480: S101 S 6004792_562_779 at #481: L102 6004792_562_779 at #481: L102 L 6004792_562_779 at #482: M103 6004792_562_779 at #482: M103 M 6004792_562_779 at #483: G104 6004792_562_779 at #483: G104 G 6004792_562_779 at #484: I105 6004792_562_779 at #484: I105 I 6004792_562_779 at #485: Y106 6004792_562_779 at #485: Y106 Y 6004792_562_779 at #486: G107 6004792_562_779 at #486: G107 G 6004792_562_779 at #487: E108 6004792_562_779 at #487: E108 E 6004792_562_779 at #530: P138 6004792_562_779 at #530: P138 P 6004792_562_779 at #532 6004792_562_779 at #532 - 6004792_562_779 at #533 6004792_562_779 at #533 - 6004792_562_779 at #534 6004792_562_779 at #534 - 6004792_562_779 at #535: A140 6004792_562_779 at #535: A140 A 6004792_562_779 at #544: E144 6004792_562_779 at #544: E144 E 6004792_562_779 at #545: Q145 6004792_562_779 at #545: Q145 Q 6004792_562_779 at #548: W146 6004792_562_779 at #548: W146 W 6004792_562_779 at #549: K147 6004792_562_779 at #549: K147 K 6004792_562_779 at #550: T148 6004792_562_779 at #550: T148 T 6004792_562_779 at #551: F149 6004792_562_779 at #551: F149 F 6004792_562_779 at #552: W150 6004792_562_779 at #552: W150 W 6004792_562_779 at #553: K151 6004792_562_779 at #553: K151 K 6004792_562_779 at #554: A152 6004792_562_779 at #554: A152 A 6004792_562_779 at #555: G153 6004792_562_779 at #555: G153 G 6004792_562_779 at #556: Q154 6004792_562_779 at #556: Q154 Q 6004792_562_779 at #557: W155 6004792_562_779 at #557: W155 W 6004792_562_779 at #558: N156 6004792_562_779 at #558: N156 N 6004792_562_779 at #559: E157 6004792_562_779 at #559: E157 E 6004792_562_779 at #560: F158 6004792_562_779 at #560: F158 F 6004792_562_779 at #561: K159 6004792_562_779 at #561: K159 K 6004792_562_779 at #562: M160 6004792_562_779 at #562: M160 M 6004792_562_779 at #565: R161 6004792_562_779 at #565: R161 R 6004792_562_779 at #566: I162 6004792_562_779 at #566: I162 I 6004792_562_779 at #568: T163 6004792_562_779 at #568: T163 T 6004792_562_779 at #570: G164 6004792_562_779 at #570: G164 G 6004792_562_779 at #571: G165 6004792_562_779 at #571: G165 G 6004792_562_779 at #572: D166 6004792_562_779 at #572: D166 D 6004792_562_779 at #588: I170 6004792_562_779 at #588: I170 I 6004792_562_779 at #589: T171 6004792_562_779 at #589: T171 T 6004792_562_779 at #592: T172 6004792_562_779 at #592: T172 T 6004792_562_779 at #594: W173 6004792_562_779 at #594: W173 W 6004792_562_779 at #595: I174 6004792_562_779 at #595: I174 I 6004792_562_779 at #596: N175 6004792_562_779 at #596: N175 N 6004792_562_779 at #598: G176 6004792_562_779 at #598: G176 G 6004792_562_779 at #599: M177 6004792_562_779 at #599: M177 M 6004792_562_779 at #600: K178 6004792_562_779 at #600: K178 K 6004792_562_779 at #601: I179 6004792_562_779 at #601: I179 I 6004792_562_779 at #602: M180 6004792_562_779 at #602: M180 M 6004792_562_779 at #603: E181 6004792_562_779 at #603: E181 E 6004792_562_779 at #604: W182 6004792_562_779 at #604: W182 W 6004792_562_779 at #605: T183 6004792_562_779 at #605: T183 T 6004792_562_779 at #606: E184 6004792_562_779 at #606: E184 E 6004792_562_779 at #607: T185 6004792_562_779 at #607: T185 T 6004792_562_779 at #608: E186 6004792_562_779 at #608: E186 E 6004792_562_779 at #609: A187 6004792_562_779 at #609: A187 A 6004792_562_779 at #610: R188 6004792_562_779 at #610: R188 R 6004792_562_779 at #611: L189 6004792_562_779 at #611: L189 L 6004792_562_779 at #612: P190 6004792_562_779 at #612: P190 P 6004792_562_779 at #613 6004792_562_779 at #613 - 6004792_562_779 at #614 6004792_562_779 at #614 - 6004792_562_779 at #615 6004792_562_779 at #615 - 6004792_562_779 at #616 6004792_562_779 at #616 - 6004792_562_779 at #640 6004792_562_779 at #640 - 6004792_562_779 at #641 6004792_562_779 at #641 - 6004792_562_779 at #642 6004792_562_779 at #642 - 6004792_562_779 at #643: V191 6004792_562_779 at #643: V191 V 6004792_562_779 at #644: A192 6004792_562_779 at #644: A192 A 6004792_562_779 at #645: G193 6004792_562_779 at #645: G193 G 6004792_562_779 at #646: N194 6004792_562_779 at #646: N194 N 6004792_562_779 at #647: I195 6004792_562_779 at #647: I195 I 6004792_562_779 at #648: G196 6004792_562_779 at #648: G196 G 6004792_562_779 at #649: L197 6004792_562_779 at #649: L197 L 6004792_562_779 at #650: Q198 6004792_562_779 at #650: Q198 Q 6004792_562_779 at #653: V199 6004792_562_779 at #653: V199 V 6004792_562_779 at #654: H200 6004792_562_779 at #654: H200 H 6004792_562_779 at #655: G201 6004792_562_779 at #655: G201 G 6004792_562_779 at #668: Q208 6004792_562_779 at #668: Q208 Q 6004792_562_779 at #689: F209 6004792_562_779 at #689: F209 F 6004792_562_779 at #690: V210 6004792_562_779 at #690: V210 V 6004792_562_779 at #691: R211 6004792_562_779 at #691: R211 R 6004792_562_779 at #694: Y212 6004792_562_779 at #694: Y212 Y 6004792_562_779 at #695: R213 6004792_562_779 at #695: R213 R 6004792_562_779 at #696: N214 6004792_562_779 at #696: N214 N 6004792_562_779 at #697: I215 6004792_562_779 at #697: I215 I 6004792_562_779 at #698: R216 6004792_562_779 at #698: R216 R 6004792_562_779 at #699: V217 6004792_562_779 at #699: V217 V 6004792_562_779 at #700: K218 6004792_562_779 at #700: K218 K single domain, near sugar dehydrogenase, from Arthrobacter chlorophenolicus A6 7352115_10_283 single domain, near sugar dehydrogenase, from Arthrobacter chlorophenolicus A6 7352115_10_283 at #155: G1 7352115_10_283 at #155: G1 G 7352115_10_283 at #156: F2 7352115_10_283 at #156: F2 F 7352115_10_283 at #157: V3 7352115_10_283 at #157: V3 V 7352115_10_283 at #158: P4 7352115_10_283 at #158: P4 P 7352115_10_283 at #159: L5 7352115_10_283 at #159: L5 L 7352115_10_283 at #160: F6 7352115_10_283 at #160: F6 F 7352115_10_283 at #162: D7 7352115_10_283 at #162: D7 D 7352115_10_283 at #164: G8 7352115_10_283 at #164: G8 G 7352115_10_283 at #165: S9 7352115_10_283 at #165: S9 S 7352115_10_283 at #168: T10 7352115_10_283 at #168: T10 T 7352115_10_283 at #169: L11 7352115_10_283 at #169: L11 L 7352115_10_283 at #171: A12 7352115_10_283 at #171: A12 A 7352115_10_283 at #172: G13 7352115_10_283 at #172: G13 G 7352115_10_283 at #180: W14 7352115_10_283 at #180: W14 W 7352115_10_283 at #181: Y15 7352115_10_283 at #181: Y15 Y 7352115_10_283 at #185: S16 7352115_10_283 at #185: S16 S 7352115_10_283 at #186: V17 7352115_10_283 at #186: V17 V 7352115_10_283 at #187: P18 7352115_10_283 at #187: P18 P 7352115_10_283 at #188: R19 7352115_10_283 at #188: R19 R 7352115_10_283 at #189: V20 7352115_10_283 at #189: V20 V 7352115_10_283 at #190: Y21 7352115_10_283 at #190: Y21 Y 7352115_10_283 at #191: G22 7352115_10_283 at #191: G22 G 7352115_10_283 at #195: T23 7352115_10_283 at #195: T23 T 7352115_10_283 at #196 7352115_10_283 at #196 - 7352115_10_283 at #197 7352115_10_283 at #197 - 7352115_10_283 at #198: E24 7352115_10_283 at #198: E24 E 7352115_10_283 at #235: F54 7352115_10_283 at #235: F54 F 7352115_10_283 at #236: A55 7352115_10_283 at #236: A55 A 7352115_10_283 at #237: E56 7352115_10_283 at #237: E56 E 7352115_10_283 at #238: D57 7352115_10_283 at #238: D57 D 7352115_10_283 at #240: G58 7352115_10_283 at #240: G58 G 7352115_10_283 at #268: V59 7352115_10_283 at #268: V59 V 7352115_10_283 at #269: L60 7352115_10_283 at #269: L60 L 7352115_10_283 at #270: V61 7352115_10_283 at #270: V61 V 7352115_10_283 at #294: T66 7352115_10_283 at #294: T66 T 7352115_10_283 at #295: P67 7352115_10_283 at #295: P67 P 7352115_10_283 at #296: G68 7352115_10_283 at #296: G68 G 7352115_10_283 at #297: S69 7352115_10_283 at #297: S69 S 7352115_10_283 at #298: G70 7352115_10_283 at #298: G70 G 7352115_10_283 at #299: Y71 7352115_10_283 at #299: Y71 Y 7352115_10_283 at #300: G72 7352115_10_283 at #300: G72 G 7352115_10_283 at #301: G73 7352115_10_283 at #301: G73 G 7352115_10_283 at #303: Y74 7352115_10_283 at #303: Y74 Y 7352115_10_283 at #304: L75 7352115_10_283 at #304: L75 L 7352115_10_283 at #305: V76 7352115_10_283 at #305: V76 V 7352115_10_283 at #306: T77 7352115_10_283 at #306: T77 T 7352115_10_283 at #312: E78 7352115_10_283 at #312: E78 E 7352115_10_283 at #318: R79 7352115_10_283 at #318: R79 R 7352115_10_283 at #321: A80 7352115_10_283 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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory