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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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Highlight proteins:

0.855 11293622_25_202: single domain, from Planctomyces brasiliensis DSM 5305 0.607 0.532 11269564_221_397: tandem domain, from Isosphaera pallida IS1B, ATCC 43644 559162_234_438: tandem domain, from Pirellula sp. 1 556011_250_415: tandem domain, from Pirellula sp. 1 1 /site single domain, from Planctomyces brasiliensis DSM 5305 11293622_25_202 single domain, from Planctomyces brasiliensis DSM 5305 tandem domain, from Isosphaera pallida IS1B, ATCC 43644 11269564_221_397 tandem domain, from Isosphaera pallida IS1B, ATCC 43644 tandem domain, from Pirellula sp. 1 559162_234_438 tandem domain, from Pirellula sp. 1 tandem domain, from Pirellula sp. 1 556011_250_415 tandem domain, from Pirellula sp. 1 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory