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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.890 4592216_152_332: single domain, from Planctomyces maris DSM 8797 6253284_153_334: single domain, from Chthoniobacter flavus Ellin428 0.2 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 single domain, from Planctomyces maris DSM 8797 4592216_152_332 single domain, from Planctomyces maris DSM 8797 4592216_152_332 at #155 4592216_152_332 at #155 - 4592216_152_332 at #156 4592216_152_332 at #156 - 4592216_152_332 at #157 4592216_152_332 at #157 - 4592216_152_332 at #158 4592216_152_332 at #158 - 4592216_152_332 at #159 4592216_152_332 at #159 - 4592216_152_332 at #160 4592216_152_332 at #160 - 4592216_152_332 at #162 4592216_152_332 at #162 - 4592216_152_332 at #164 4592216_152_332 at #164 - 4592216_152_332 at #165 4592216_152_332 at #165 - 4592216_152_332 at #168 4592216_152_332 at #168 - 4592216_152_332 at #169 4592216_152_332 at #169 - 4592216_152_332 at #171 4592216_152_332 at #171 - 4592216_152_332 at #172 4592216_152_332 at #172 - 4592216_152_332 at #180 4592216_152_332 at #180 - 4592216_152_332 at #181 4592216_152_332 at #181 - 4592216_152_332 at #185 4592216_152_332 at #185 - 4592216_152_332 at #186 4592216_152_332 at #186 - 4592216_152_332 at #187 4592216_152_332 at #187 - 4592216_152_332 at #188 4592216_152_332 at #188 - 4592216_152_332 at #189 4592216_152_332 at #189 - 4592216_152_332 at #190 4592216_152_332 at #190 - 4592216_152_332 at #191 4592216_152_332 at #191 - 4592216_152_332 at #195: Q12 4592216_152_332 at #195: Q12 Q 4592216_152_332 at #196: T13 4592216_152_332 at #196: T13 T 4592216_152_332 at #197: V14 4592216_152_332 at #197: V14 V 4592216_152_332 at #198: K15 4592216_152_332 at #198: K15 K 4592216_152_332 at #235: N16 4592216_152_332 at #235: N16 N 4592216_152_332 at #236: F17 4592216_152_332 at #236: F17 F 4592216_152_332 at #237: E18 4592216_152_332 at #237: E18 E 4592216_152_332 at #238: N19 4592216_152_332 at #238: N19 N 4592216_152_332 at #240: G20 4592216_152_332 at #240: G20 G 4592216_152_332 at #268: Q21 4592216_152_332 at #268: Q21 Q 4592216_152_332 at #269: I22 4592216_152_332 at #269: I22 I 4592216_152_332 at #270: T23 4592216_152_332 at #270: T23 T 4592216_152_332 at #294 4592216_152_332 at #294 - 4592216_152_332 at #295: E24 4592216_152_332 at #295: E24 E 4592216_152_332 at #296: E25 4592216_152_332 at #296: E25 E 4592216_152_332 at #297: G26 4592216_152_332 at #297: G26 G 4592216_152_332 at #298: L27 4592216_152_332 at #298: L27 L 4592216_152_332 at #299: L28 4592216_152_332 at #299: L28 L 4592216_152_332 at #300: K29 4592216_152_332 at #300: K29 K 4592216_152_332 at #301: E30 4592216_152_332 at #301: E30 E 4592216_152_332 at #303: G31 4592216_152_332 at #303: G31 G 4592216_152_332 at #304: V32 4592216_152_332 at #304: V32 V 4592216_152_332 at #305: T33 4592216_152_332 at #305: T33 T 4592216_152_332 at #306: S34 4592216_152_332 at #306: S34 S 4592216_152_332 at #312: K35 4592216_152_332 at #312: K35 K 4592216_152_332 at #318: K36 4592216_152_332 at #318: K36 K 4592216_152_332 at #321: K37 4592216_152_332 at #321: K37 K 4592216_152_332 at #322: F38 4592216_152_332 at #322: F38 F 4592216_152_332 at #324: K39 4592216_152_332 at #324: K39 K 4592216_152_332 at #326: D40 4592216_152_332 at #326: D40 D 4592216_152_332 at #327: G41 4592216_152_332 at #327: G41 G 4592216_152_332 at #328: H42 4592216_152_332 at #328: H42 H 4592216_152_332 at #329: L43 4592216_152_332 at #329: L43 L 4592216_152_332 at #330: H44 4592216_152_332 at #330: H44 H 4592216_152_332 at #331: L45 4592216_152_332 at #331: L45 L 4592216_152_332 at #332: E46 4592216_152_332 at #332: E46 E 4592216_152_332 at #333: F47 4592216_152_332 at #333: F47 F 4592216_152_332 at #334: Q48 4592216_152_332 at #334: Q48 Q 4592216_152_332 at #335: L49 4592216_152_332 at #335: L49 L 4592216_152_332 at #351: R56 4592216_152_332 at #351: R56 R 4592216_152_332 at #352 4592216_152_332 at #352 - 4592216_152_332 at #354 4592216_152_332 at #354 - 4592216_152_332 at #355: G57 4592216_152_332 at #355: G57 G 4592216_152_332 at #385: N62 4592216_152_332 at #385: N62 N 4592216_152_332 at #386: S63 4592216_152_332 at #386: S63 S 4592216_152_332 at #387: G64 4592216_152_332 at #387: G64 G 4592216_152_332 at #388: C65 4592216_152_332 at #388: C65 C 4592216_152_332 at #389: Y66 4592216_152_332 at #389: Y66 Y 4592216_152_332 at #390: V67 4592216_152_332 at #390: V67 V 4592216_152_332 at #391: L68 4592216_152_332 at #391: L68 L 4592216_152_332 at #392: G69 4592216_152_332 at #392: G69 G 4592216_152_332 at #393: R70 4592216_152_332 at #393: R70 R 4592216_152_332 at #423 4592216_152_332 at #423 - 4592216_152_332 at #424 4592216_152_332 at #424 - 4592216_152_332 at #425 4592216_152_332 at #425 - 4592216_152_332 at #426 4592216_152_332 at #426 - 4592216_152_332 at #430 4592216_152_332 at #430 - 4592216_152_332 at #431 4592216_152_332 at #431 - 4592216_152_332 at #432 4592216_152_332 at #432 - 4592216_152_332 at #433 4592216_152_332 at #433 - 4592216_152_332 at #434 4592216_152_332 at #434 - 4592216_152_332 at #435 4592216_152_332 at #435 - 4592216_152_332 at #436: Y71 4592216_152_332 at #436: Y71 Y 4592216_152_332 at #438: E72 4592216_152_332 at #438: E72 E 4592216_152_332 at #439: V73 4592216_152_332 at #439: V73 V 4592216_152_332 at #440: Q74 4592216_152_332 at #440: Q74 Q 4592216_152_332 at #441: I75 4592216_152_332 at #441: I75 I 4592216_152_332 at #442: L76 4592216_152_332 at #442: L76 L 4592216_152_332 at #443: D77 4592216_152_332 at #443: D77 D 4592216_152_332 at #450: S78 4592216_152_332 at #450: S78 S 4592216_152_332 at #451: F79 4592216_152_332 at #451: F79 F 4592216_152_332 at #452: G80 4592216_152_332 at #452: G80 G 4592216_152_332 at #453: L81 4592216_152_332 at #453: L81 L 4592216_152_332 at #475: E82 4592216_152_332 at #475: E82 E 4592216_152_332 at #476: G83 4592216_152_332 at #476: G83 G 4592216_152_332 at #477: K84 4592216_152_332 at #477: K84 K 4592216_152_332 at #478: D85 4592216_152_332 at #478: D85 D 4592216_152_332 at #479: N86 4592216_152_332 at #479: N86 N 4592216_152_332 at #480: E87 4592216_152_332 at #480: E87 E 4592216_152_332 at #481: C88 4592216_152_332 at #481: C88 C 4592216_152_332 at #482: G89 4592216_152_332 at #482: G89 G 4592216_152_332 at #483: G90 4592216_152_332 at #483: G90 G 4592216_152_332 at #484: I91 4592216_152_332 at #484: I91 I 4592216_152_332 at #485: Y92 4592216_152_332 at #485: Y92 Y 4592216_152_332 at #486 4592216_152_332 at #486 - 4592216_152_332 at #487 4592216_152_332 at #487 - 4592216_152_332 at #530 4592216_152_332 at #530 - 4592216_152_332 at #532: K93 4592216_152_332 at #532: K93 K 4592216_152_332 at #533: L94 4592216_152_332 at #533: L94 L 4592216_152_332 at #534: G95 4592216_152_332 at #534: G95 G 4592216_152_332 at #535: A96 4592216_152_332 at #535: A96 A 4592216_152_332 at #544: P97 4592216_152_332 at #544: P97 P 4592216_152_332 at #545: S98 4592216_152_332 at #545: S98 S 4592216_152_332 at #548: V99 4592216_152_332 at #548: V99 V 4592216_152_332 at #549: N100 4592216_152_332 at #549: N100 N 4592216_152_332 at #550: M101 4592216_152_332 at #550: M101 M 4592216_152_332 at #551: C102 4592216_152_332 at #551: C102 C 4592216_152_332 at #552: F103 4592216_152_332 at #552: F103 F 4592216_152_332 at #553: P104 4592216_152_332 at #553: P104 P 4592216_152_332 at #554: P105 4592216_152_332 at #554: P105 P 4592216_152_332 at #555: L106 4592216_152_332 at #555: L106 L 4592216_152_332 at #556: A107 4592216_152_332 at #556: A107 A 4592216_152_332 at #557: W108 4592216_152_332 at #557: W108 W 4592216_152_332 at #558: Q109 4592216_152_332 at #558: Q109 Q 4592216_152_332 at #559: T110 4592216_152_332 at #559: T110 T 4592216_152_332 at #560: Y111 4592216_152_332 at #560: Y111 Y 4592216_152_332 at #561: D112 4592216_152_332 at #561: D112 D 4592216_152_332 at #562: I113 4592216_152_332 at #562: I113 I 4592216_152_332 at #565: D114 4592216_152_332 at #565: D114 D 4592216_152_332 at #566: F115 4592216_152_332 at #566: F115 F 4592216_152_332 at #568: Q116 4592216_152_332 at #568: Q116 Q 4592216_152_332 at #570: S117 4592216_152_332 at #570: S117 S 4592216_152_332 at #571: A118 4592216_152_332 at #571: A118 A 4592216_152_332 at #572: K119 4592216_152_332 at #572: K119 K 4592216_152_332 at #588: I132 4592216_152_332 at #588: I132 I 4592216_152_332 at #589: T133 4592216_152_332 at #589: T133 T 4592216_152_332 at #592: V134 4592216_152_332 at #592: V134 V 4592216_152_332 at #594: K135 4592216_152_332 at #594: K135 K 4592216_152_332 at #595: H136 4592216_152_332 at #595: H136 H 4592216_152_332 at #596: N137 4592216_152_332 at #596: N137 N 4592216_152_332 at #598: G138 4592216_152_332 at #598: G138 G 4592216_152_332 at #599: V139 4592216_152_332 at #599: V139 V 4592216_152_332 at #600: T140 4592216_152_332 at #600: T140 T 4592216_152_332 at #601: V141 4592216_152_332 at #601: V141 V 4592216_152_332 at #602: Q142 4592216_152_332 at #602: Q142 Q 4592216_152_332 at #603: D143 4592216_152_332 at #603: D143 D 4592216_152_332 at #604: D144 4592216_152_332 at #604: D144 D 4592216_152_332 at #605: Q145 4592216_152_332 at #605: Q145 Q 4592216_152_332 at #606: E146 4592216_152_332 at #606: E146 E 4592216_152_332 at #607: I147 4592216_152_332 at #607: I147 I 4592216_152_332 at #608: N148 4592216_152_332 at #608: N148 N 4592216_152_332 at #609: E149 4592216_152_332 at #609: E149 E 4592216_152_332 at #610: P150 4592216_152_332 at #610: P150 P 4592216_152_332 at #611: T151 4592216_152_332 at #611: T151 T 4592216_152_332 at #612: P152 4592216_152_332 at #612: P152 P 4592216_152_332 at #613: G153 4592216_152_332 at #613: G153 G 4592216_152_332 at #614: G154 4592216_152_332 at #614: G154 G 4592216_152_332 at #615: T155 4592216_152_332 at #615: T155 T 4592216_152_332 at #616: N156 4592216_152_332 at #616: N156 N 4592216_152_332 at #640: D158 4592216_152_332 at #640: D158 D 4592216_152_332 at #641: E159 4592216_152_332 at #641: E159 E 4592216_152_332 at #642: S160 4592216_152_332 at #642: S160 S 4592216_152_332 at #643: I161 4592216_152_332 at #643: I161 I 4592216_152_332 at #644: A162 4592216_152_332 at #644: A162 A 4592216_152_332 at #645: G163 4592216_152_332 at #645: G163 G 4592216_152_332 at #646: P164 4592216_152_332 at #646: P164 P 4592216_152_332 at #647: L165 4592216_152_332 at #647: L165 L 4592216_152_332 at #648: F166 4592216_152_332 at #648: F166 F 4592216_152_332 at #649: L167 4592216_152_332 at #649: L167 L 4592216_152_332 at #650: Q168 4592216_152_332 at #650: Q168 Q 4592216_152_332 at #653: N169 4592216_152_332 at #653: N169 N 4592216_152_332 at #654: H170 4592216_152_332 at #654: H170 H 4592216_152_332 at #655: S171 4592216_152_332 at #655: S171 S 4592216_152_332 at #668: N172 4592216_152_332 at #668: N172 N 4592216_152_332 at #689: P173 4592216_152_332 at #689: P173 P 4592216_152_332 at #690: V174 4592216_152_332 at #690: V174 V 4592216_152_332 at #691: R175 4592216_152_332 at #691: R175 R 4592216_152_332 at #694: F176 4592216_152_332 at #694: F176 F 4592216_152_332 at #695: R177 4592216_152_332 at #695: R177 R 4592216_152_332 at #696: N178 4592216_152_332 at #696: N178 N 4592216_152_332 at #697: I179 4592216_152_332 at #697: I179 I 4592216_152_332 at #698: W180 4592216_152_332 at #698: W180 W 4592216_152_332 at #699: V181 4592216_152_332 at #699: V181 V 4592216_152_332 at #700 4592216_152_332 at #700 - single domain, from Chthoniobacter flavus Ellin428 6253284_153_334 single domain, from Chthoniobacter flavus Ellin428 6253284_153_334 at #155: G1 6253284_153_334 at #155: G1 G 6253284_153_334 at #156: A2 6253284_153_334 at #156: A2 A 6253284_153_334 at #157: I3 6253284_153_334 at #157: I3 I 6253284_153_334 at #158: V4 6253284_153_334 at #158: V4 V 6253284_153_334 at #159: L5 6253284_153_334 at #159: L5 L 6253284_153_334 at #160: F6 6253284_153_334 at #160: F6 F 6253284_153_334 at #162: D7 6253284_153_334 at #162: D7 D 6253284_153_334 at #164: G8 6253284_153_334 at #164: G8 G 6253284_153_334 at #165: T9 6253284_153_334 at #165: T9 T 6253284_153_334 at #168: N10 6253284_153_334 at #168: N10 N 6253284_153_334 at #169: L11 6253284_153_334 at #169: L11 L 6253284_153_334 at #171: D12 6253284_153_334 at #171: D12 D 6253284_153_334 at #172: E13 6253284_153_334 at #172: E13 E 6253284_153_334 at #180: W14 6253284_153_334 at #180: W14 W 6253284_153_334 at #181: E15 6253284_153_334 at #181: E15 E 6253284_153_334 at #185: P16 6253284_153_334 at #185: P16 P 6253284_153_334 at #186: G17 6253284_153_334 at #186: G17 G 6253284_153_334 at #187: A18 6253284_153_334 at #187: A18 A 6253284_153_334 at #188: R19 6253284_153_334 at #188: R19 R 6253284_153_334 at #189 6253284_153_334 at #189 - 6253284_153_334 at #190 6253284_153_334 at #190 - 6253284_153_334 at #191 6253284_153_334 at #191 - 6253284_153_334 at #195 6253284_153_334 at #195 - 6253284_153_334 at #196 6253284_153_334 at #196 - 6253284_153_334 at #197 6253284_153_334 at #197 - 6253284_153_334 at #198 6253284_153_334 at #198 - 6253284_153_334 at #235: M20 6253284_153_334 at #235: M20 M 6253284_153_334 at #236: T21 6253284_153_334 at #236: T21 T 6253284_153_334 at #237: E22 6253284_153_334 at #237: E22 E 6253284_153_334 at #238: N23 6253284_153_334 at #238: N23 N 6253284_153_334 at #240: K24 6253284_153_334 at #240: K24 K 6253284_153_334 at #268: W25 6253284_153_334 at #268: W25 W 6253284_153_334 at #269: I26 6253284_153_334 at #269: I26 I 6253284_153_334 at #270: T27 6253284_153_334 at #270: T27 T 6253284_153_334 at #294 6253284_153_334 at #294 - 6253284_153_334 at #295 6253284_153_334 at #295 - 6253284_153_334 at #296 6253284_153_334 at #296 - 6253284_153_334 at #297 6253284_153_334 at #297 - 6253284_153_334 at #298: S28 6253284_153_334 at #298: S28 S 6253284_153_334 at #299: E29 6253284_153_334 at #299: E29 E 6253284_153_334 at #300: G30 6253284_153_334 at #300: G30 G 6253284_153_334 at #301: K31 6253284_153_334 at #301: K31 K 6253284_153_334 at #303: G32 6253284_153_334 at #303: G32 G 6253284_153_334 at #304: A33 6253284_153_334 at #304: A33 A 6253284_153_334 at #305: T34 6253284_153_334 at #305: T34 T 6253284_153_334 at #306: T35 6253284_153_334 at #306: T35 T 6253284_153_334 at #312: K36 6253284_153_334 at #312: K36 K 6253284_153_334 at #318: R37 6253284_153_334 at #318: R37 R 6253284_153_334 at #321: K38 6253284_153_334 at #321: K38 K 6253284_153_334 at #322: F39 6253284_153_334 at #322: F39 F 6253284_153_334 at #324: E40 6253284_153_334 at #324: E40 E 6253284_153_334 at #326: D41 6253284_153_334 at #326: D41 D 6253284_153_334 at #327: F42 6253284_153_334 at #327: F42 F 6253284_153_334 at #328: T43 6253284_153_334 at #328: T43 T 6253284_153_334 at #329: L44 6253284_153_334 at #329: L44 L 6253284_153_334 at #330: H45 6253284_153_334 at #330: H45 H 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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory