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Showing 186 alignment positions (of 716) that are less than half gaps or lower-case

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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.870 554416_28_225: with redox domain, from Pirellula sp. 1 4611874_988_1186: with redox domain, from Lentisphaera araneosa HTCC2155 0.5 /site amino acids:gapgap-alaninealanineAcysteinecysteineCaspartateaspartateDglutamateglutamateEphenylalaninephenylalanineFglycineglycineGhistidinehistidineHisoleucineisoleucineIlysinelysineKleucineleucineLmethioninemethionineMasparagineasparagineNprolineprolinePglutamineglutamineQargininearginineRserineserineSthreoninethreonineTvalinevalineVtryptophantryptophanWtyrosinetyrosineY Alignment position 560#560 Alignment position 385#385 Alignment position 566#566 Alignment position 387#387 Alignment position 332#332 Alignment position 561#561 Alignment position 533#533 Alignment position 330#330 Alignment position 600#600 Alignment position 610#610 Alignment position 588#588 Alignment position 668#668 Alignment position 191#191 Alignment position 162#162 Alignment position 438#438 Alignment position 299#299 Alignment position 195#195 Alignment position 425#425 Alignment position 535#535 Alignment position 452#452 Alignment position 602#602 Alignment position 164#164 Alignment position 552#552 Alignment position 530#530 Alignment position 612#612 Alignment position 558#558 Alignment position 698#698 Alignment position 696#696 Alignment position 476#476 Alignment position 442#442 Alignment position 435#435 Alignment position 295#295 Alignment position 158#158 Alignment position 326#326 Alignment position 351#351 Alignment position 198#198 Alignment position 443#443 Alignment position 430#430 Alignment position 650#650 Alignment position 607#607 Alignment position 432#432 Alignment position 690#690 Alignment position 649#649 Alignment position 643#643 Alignment position 433#433 Alignment position 322#322 Alignment position 312#312 Alignment position 572#572 Alignment position 390#390 Alignment position 436#436 Alignment position 328#328 Alignment position 549#549 Alignment position 321#321 Alignment position 187#187 Alignment position 334#334 Alignment position 237#237 Alignment position 324#324 Alignment position 532#532 Alignment position 169#169 Alignment position 269#269 Alignment position 185#185 Alignment position 188#188 Alignment position 614#614 Alignment position 589#589 Alignment position 647#647 Alignment position 386#386 Alignment position 235#235 Alignment position 595#595 Alignment position 640#640 Alignment position 155#155 Alignment position 389#389 Alignment position 654#654 Alignment position 554#554 Alignment position 480#480 Alignment position 160#160 Alignment position 487#487 Alignment position 327#327 Alignment position 562#562 Alignment position 570#570 Alignment position 556#556 Alignment position 484#484 Alignment position 699#699 Alignment position 486#486 Alignment position 196#196 Alignment position 644#644 Alignment position 171#171 Alignment position 392#392 Alignment position 555#555 Alignment position 601#601 Alignment position 553#553 Alignment position 181#181 Alignment position 599#599 Alignment position 180#180 Alignment position 697#697 Alignment position 434#434 Alignment position 352#352 Alignment position 648#648 Alignment position 298#298 Alignment position 596#596 Alignment position 335#335 Alignment position 534#534 Alignment position 441#441 Alignment position 691#691 Alignment position 300#300 Alignment position 605#605 Alignment position 431#431 Alignment position 603#603 Alignment position 557#557 Alignment position 478#478 Alignment position 424#424 Alignment position 551#551 Alignment position 190#190 Alignment position 613#613 Alignment position 331#331 Alignment position 453#453 Alignment position 296#296 Alignment position 168#168 Alignment position 481#481 Alignment position 439#439 Alignment position 611#611 Alignment position 475#475 Alignment position 482#482 Alignment position 423#423 Alignment position 616#616 Alignment position 565#565 Alignment position 305#305 Alignment position 477#477 Alignment position 548#548 Alignment position 559#559 Alignment position 689#689 Alignment position 483#483 Alignment position 303#303 Alignment position 450#450 Alignment position 294#294 Alignment position 238#238 Alignment position 694#694 Alignment position 550#550 Alignment position 594#594 Alignment position 189#189 Alignment position 646#646 Alignment position 568#568 Alignment position 354#354 Alignment position 642#642 Alignment position 655#655 Alignment position 571#571 Alignment position 301#301 Alignment position 641#641 Alignment position 157#157 Alignment position 304#304 Alignment position 485#485 Alignment position 306#306 Alignment position 615#615 Alignment position 700#700 Alignment position 393#393 Alignment position 451#451 Alignment position 545#545 Alignment position 606#606 Alignment position 156#156 Alignment position 388#388 Alignment position 329#329 Alignment position 240#240 Alignment position 608#608 Alignment position 268#268 Alignment position 544#544 Alignment position 270#270 Alignment position 159#159 Alignment position 645#645 Alignment position 355#355 Alignment position 236#236 Alignment position 695#695 Alignment position 186#186 Alignment position 598#598 Alignment position 333#333 Alignment position 391#391 Alignment position 426#426 Alignment position 592#592 Alignment position 440#440 Alignment position 653#653 Alignment position 318#318 Alignment position 297#297 Alignment position 609#609 Alignment position 165#165 Alignment position 197#197 Alignment position 604#604 Alignment position 172#172 Alignment position 479#479 with redox domain, from Pirellula sp. 1 554416_28_225 with redox domain, from Pirellula sp. 1 554416_28_225 at #155 554416_28_225 at #155 - 554416_28_225 at #156: F1 554416_28_225 at #156: F1 F 554416_28_225 at #157: E2 554416_28_225 at #157: E2 E 554416_28_225 at #158: N3 554416_28_225 at #158: N3 N 554416_28_225 at #159: L4 554416_28_225 at #159: L4 L 554416_28_225 at #160: F5 554416_28_225 at #160: F5 F 554416_28_225 at #162: N6 554416_28_225 at #162: N6 N 554416_28_225 at #164: G7 554416_28_225 at #164: G7 G 554416_28_225 at #165: K8 554416_28_225 at #165: K8 K 554416_28_225 at #168: D9 554416_28_225 at #168: D9 D 554416_28_225 at #169: L10 554416_28_225 at #169: L10 L 554416_28_225 at #171: S11 554416_28_225 at #171: S11 S 554416_28_225 at #172: G12 554416_28_225 at #172: G12 G 554416_28_225 at #180: W13 554416_28_225 at #180: W13 W 554416_28_225 at #181: A14 554416_28_225 at #181: A14 A 554416_28_225 at #185: G15 554416_28_225 at #185: G15 G 554416_28_225 at #186: N16 554416_28_225 at #186: N16 N 554416_28_225 at #187: D17 554416_28_225 at #187: D17 D 554416_28_225 at #188: S18 554416_28_225 at #188: S18 S 554416_28_225 at #189 554416_28_225 at #189 - 554416_28_225 at #190 554416_28_225 at #190 - 554416_28_225 at #191 554416_28_225 at #191 - 554416_28_225 at #195 554416_28_225 at #195 - 554416_28_225 at #196 554416_28_225 at #196 - 554416_28_225 at #197: F19 554416_28_225 at #197: F19 F 554416_28_225 at #198: W20 554416_28_225 at #198: W20 W 554416_28_225 at #235: S21 554416_28_225 at #235: S21 S 554416_28_225 at #236: V22 554416_28_225 at #236: V22 V 554416_28_225 at #237: R23 554416_28_225 at #237: R23 R 554416_28_225 at #238: D24 554416_28_225 at #238: D24 D 554416_28_225 at #240: G25 554416_28_225 at #240: G25 G 554416_28_225 at #268: V26 554416_28_225 at #268: V26 V 554416_28_225 at #269: I27 554416_28_225 at #269: I27 I 554416_28_225 at #270: H28 554416_28_225 at #270: H28 H 554416_28_225 at #294: E34 554416_28_225 at #294: E34 E 554416_28_225 at #295: N35 554416_28_225 at #295: N35 N 554416_28_225 at #296: P36 554416_28_225 at #296: P36 P 554416_28_225 at #297: T37 554416_28_225 at #297: T37 T 554416_28_225 at #298: K38 554416_28_225 at #298: K38 K 554416_28_225 at #299: G39 554416_28_225 at #299: G39 G 554416_28_225 at #300: N40 554416_28_225 at #300: N40 N 554416_28_225 at #301: T41 554416_28_225 at #301: T41 T 554416_28_225 at #303: F42 554416_28_225 at #303: F42 F 554416_28_225 at #304: L43 554416_28_225 at #304: L43 L 554416_28_225 at #305: V44 554416_28_225 at #305: V44 V 554416_28_225 at #306: W45 554416_28_225 at #306: W45 W 554416_28_225 at #312: Q46 554416_28_225 at #312: Q46 Q 554416_28_225 at #318: G47 554416_28_225 at #318: G47 G 554416_28_225 at #321: E49 554416_28_225 at #321: E49 E 554416_28_225 at #322: V50 554416_28_225 at #322: V50 V 554416_28_225 at #324: G51 554416_28_225 at #324: G51 G 554416_28_225 at #326: D52 554416_28_225 at #326: D52 D 554416_28_225 at #327: F53 554416_28_225 at #327: F53 F 554416_28_225 at #328: V54 554416_28_225 at #328: V54 V 554416_28_225 at #329: F55 554416_28_225 at #329: F55 F 554416_28_225 at #330: K56 554416_28_225 at #330: K56 K 554416_28_225 at #331: T57 554416_28_225 at #331: T57 T 554416_28_225 at #332: K58 554416_28_225 at #332: K58 K 554416_28_225 at #333: V59 554416_28_225 at #333: V59 V 554416_28_225 at #334: R60 554416_28_225 at #334: R60 R 554416_28_225 at #335 554416_28_225 at #335 - 554416_28_225 at #351: F61 554416_28_225 at #351: F61 F 554416_28_225 at #352: R62 554416_28_225 at #352: R62 R 554416_28_225 at #354: G63 554416_28_225 at #354: G63 G 554416_28_225 at #355: N64 554416_28_225 at #355: N64 N 554416_28_225 at #385: N65 554416_28_225 at #385: N65 N 554416_28_225 at #386: S66 554416_28_225 at #386: S66 S 554416_28_225 at #387: G67 554416_28_225 at #387: G67 G 554416_28_225 at #388: V68 554416_28_225 at #388: V68 V 554416_28_225 at #389: Q69 554416_28_225 at #389: Q69 Q 554416_28_225 at #390: Y70 554416_28_225 at #390: Y70 Y 554416_28_225 at #391: R71 554416_28_225 at #391: R71 R 554416_28_225 at #392: S72 554416_28_225 at #392: S72 S 554416_28_225 at #393: E73 554416_28_225 at #393: E73 E 554416_28_225 at #423: I75 554416_28_225 at #423: I75 I 554416_28_225 at #424: D76 554416_28_225 at #424: D76 D 554416_28_225 at #425: P77 554416_28_225 at #425: P77 P 554416_28_225 at #426: K78 554416_28_225 at #426: K78 K 554416_28_225 at #430: E79 554416_28_225 at #430: E79 E 554416_28_225 at #431: F80 554416_28_225 at #431: F80 F 554416_28_225 at #432: V81 554416_28_225 at #432: V81 V 554416_28_225 at #433: V82 554416_28_225 at #433: V82 V 554416_28_225 at #434: K83 554416_28_225 at #434: K83 K 554416_28_225 at #435: G84 554416_28_225 at #435: G84 G 554416_28_225 at #436: Y85 554416_28_225 at #436: Y85 Y 554416_28_225 at #438: Q86 554416_28_225 at #438: Q86 Q 554416_28_225 at #439: A87 554416_28_225 at #439: A87 A 554416_28_225 at #440: D88 554416_28_225 at #440: D88 D 554416_28_225 at #441: L89 554416_28_225 at #441: L89 L 554416_28_225 at #442: H90 554416_28_225 at #442: H90 H 554416_28_225 at #443: K91 554416_28_225 at #443: K91 K 554416_28_225 at #450: S92 554416_28_225 at #450: S92 S 554416_28_225 at #451 554416_28_225 at #451 - 554416_28_225 at #452 554416_28_225 at #452 - 554416_28_225 at #453 554416_28_225 at #453 - 554416_28_225 at #475 554416_28_225 at #475 - 554416_28_225 at #476 554416_28_225 at #476 - 554416_28_225 at #477 554416_28_225 at #477 - 554416_28_225 at #478: P93 554416_28_225 at #478: P93 P 554416_28_225 at #479: D94 554416_28_225 at #479: D94 D 554416_28_225 at #480: F95 554416_28_225 at #480: F95 F 554416_28_225 at #481: F96 554416_28_225 at #481: F96 F 554416_28_225 at #482: G97 554416_28_225 at #482: G97 G 554416_28_225 at #483: M98 554416_28_225 at #483: M98 M 554416_28_225 at #484: L99 554416_28_225 at #484: L99 L 554416_28_225 at #485: Y100 554416_28_225 at #485: Y100 Y 554416_28_225 at #486: A101 554416_28_225 at #486: A101 A 554416_28_225 at #487: E102 554416_28_225 at #487: E102 E 554416_28_225 at #530: K124 554416_28_225 at #530: K124 K 554416_28_225 at #532 554416_28_225 at #532 - 554416_28_225 at #533: V125 554416_28_225 at #533: V125 V 554416_28_225 at #534: V126 554416_28_225 at #534: V126 V 554416_28_225 at #535: G127 554416_28_225 at #535: G127 G 554416_28_225 at #544: G130 554416_28_225 at #544: G130 G 554416_28_225 at #545: D131 554416_28_225 at #545: D131 D 554416_28_225 at #548: R132 554416_28_225 at #548: R132 R 554416_28_225 at #549: S133 554416_28_225 at #549: S133 S 554416_28_225 at #550: Q134 554416_28_225 at #550: Q134 Q 554416_28_225 at #551: K135 554416_28_225 at #551: K135 K 554416_28_225 at #552: L136 554416_28_225 at #552: L136 L 554416_28_225 at #553: V137 554416_28_225 at #553: V137 V 554416_28_225 at #554: D138 554416_28_225 at #554: D138 D 554416_28_225 at #555: W139 554416_28_225 at #555: W139 W 554416_28_225 at #556: E140 554416_28_225 at #556: E140 E 554416_28_225 at #557: W141 554416_28_225 at #557: W141 W 554416_28_225 at #558: N142 554416_28_225 at #558: N142 N 554416_28_225 at #559: E143 554416_28_225 at #559: E143 E 554416_28_225 at #560: L144 554416_28_225 at #560: L144 L 554416_28_225 at #561: T145 554416_28_225 at #561: T145 T 554416_28_225 at #562: I146 554416_28_225 at #562: I146 I 554416_28_225 at #565: I147 554416_28_225 at #565: I147 I 554416_28_225 at #566: A148 554416_28_225 at #566: A148 A 554416_28_225 at #568: V149 554416_28_225 at #568: V149 V 554416_28_225 at #570: G150 554416_28_225 at #570: G150 G 554416_28_225 at #571: D151 554416_28_225 at #571: D151 D 554416_28_225 at #572: R152 554416_28_225 at #572: R152 R 554416_28_225 at #588: Q153 554416_28_225 at #588: Q153 Q 554416_28_225 at #589: I154 554416_28_225 at #589: I154 I 554416_28_225 at #592: H155 554416_28_225 at #592: H155 H 554416_28_225 at #594: Q156 554416_28_225 at #594: Q156 Q 554416_28_225 at #595: V157 554416_28_225 at #595: V157 V 554416_28_225 at #596: N158 554416_28_225 at #596: N158 N 554416_28_225 at #598: G159 554416_28_225 at #598: G159 G 554416_28_225 at #599: V160 554416_28_225 at #599: V160 V 554416_28_225 at #600: T161 554416_28_225 at #600: T161 T 554416_28_225 at #601: T162 554416_28_225 at #601: T162 T 554416_28_225 at #602: M163 554416_28_225 at #602: M163 M 554416_28_225 at #603: D164 554416_28_225 at #603: D164 D 554416_28_225 at #604: L165 554416_28_225 at #604: L165 L 554416_28_225 at #605: T166 554416_28_225 at #605: T166 T 554416_28_225 at #606: D167 554416_28_225 at #606: D167 D 554416_28_225 at #607: N168 554416_28_225 at #607: N168 N 554416_28_225 at #608: H169 554416_28_225 at #608: H169 H 554416_28_225 at #609: P170 554416_28_225 at #609: P170 P 554416_28_225 at #610: E171 554416_28_225 at #610: E171 E 554416_28_225 at #611: A172 554416_28_225 at #611: A172 A 554416_28_225 at #612: R173 554416_28_225 at #612: R173 R 554416_28_225 at #613 554416_28_225 at #613 - 554416_28_225 at #614 554416_28_225 at #614 - 554416_28_225 at #615 554416_28_225 at #615 - 554416_28_225 at #616 554416_28_225 at #616 - 554416_28_225 at #640 554416_28_225 at #640 - 554416_28_225 at #641 554416_28_225 at #641 - 554416_28_225 at #642 554416_28_225 at #642 - 554416_28_225 at #643: R174 554416_28_225 at #643: R174 R 554416_28_225 at #644: S175 554416_28_225 at #644: S175 S 554416_28_225 at #645: G176 554416_28_225 at #645: G176 G 554416_28_225 at #646: I177 554416_28_225 at #646: I177 I 554416_28_225 at #647: L178 554416_28_225 at #647: L178 L 554416_28_225 at #648: A179 554416_28_225 at #648: A179 A 554416_28_225 at #649: L180 554416_28_225 at #649: L180 L 554416_28_225 at #650: Q181 554416_28_225 at #650: Q181 Q 554416_28_225 at #653: L182 554416_28_225 at #653: L182 L 554416_28_225 at #654: H183 554416_28_225 at #654: H183 H 554416_28_225 at #655: A184 554416_28_225 at #655: A184 A 554416_28_225 at #668: M188 554416_28_225 at #668: M188 M 554416_28_225 at #689: T189 554416_28_225 at #689: T189 T 554416_28_225 at #690: C190 554416_28_225 at #690: C190 C 554416_28_225 at #691: E191 554416_28_225 at #691: E191 E 554416_28_225 at #694: F192 554416_28_225 at #694: F192 F 554416_28_225 at #695: K193 554416_28_225 at #695: K193 K 554416_28_225 at #696: D194 554416_28_225 at #696: D194 D 554416_28_225 at #697: V195 554416_28_225 at #697: V195 V 554416_28_225 at #698: Q196 554416_28_225 at #698: Q196 Q 554416_28_225 at #699: L197 554416_28_225 at #699: L197 L 554416_28_225 at #700: R198 554416_28_225 at #700: R198 R with redox domain, from Lentisphaera araneosa HTCC2155 4611874_988_1186 with redox domain, from Lentisphaera araneosa HTCC2155 4611874_988_1186 at #155: G1 4611874_988_1186 at #155: G1 G 4611874_988_1186 at #156: A2 4611874_988_1186 at #156: A2 A 4611874_988_1186 at #157: T3 4611874_988_1186 at #157: T3 T 4611874_988_1186 at #158: S4 4611874_988_1186 at #158: S4 S 4611874_988_1186 at #159: L5 4611874_988_1186 at #159: L5 L 4611874_988_1186 at #160: F6 4611874_988_1186 at #160: F6 F 4611874_988_1186 at #162: N7 4611874_988_1186 at #162: N7 N 4611874_988_1186 at #164: G8 4611874_988_1186 at #164: G8 G 4611874_988_1186 at #165: K9 4611874_988_1186 at #165: K9 K 4611874_988_1186 at #168: D10 4611874_988_1186 at #168: D10 D 4611874_988_1186 at #169: L11 4611874_988_1186 at #169: L11 L 4611874_988_1186 at #171: T12 4611874_988_1186 at #171: T12 T 4611874_988_1186 at #172: G13 4611874_988_1186 at #172: G13 G 4611874_988_1186 at #180: W14 4611874_988_1186 at #180: W14 W 4611874_988_1186 at #181: A15 4611874_988_1186 at #181: A15 A 4611874_988_1186 at #185: G16 4611874_988_1186 at #185: G16 G 4611874_988_1186 at #186: D17 4611874_988_1186 at #186: D17 D 4611874_988_1186 at #187 4611874_988_1186 at #187 - 4611874_988_1186 at #188 4611874_988_1186 at #188 - 4611874_988_1186 at #189 4611874_988_1186 at #189 - 4611874_988_1186 at #190 4611874_988_1186 at #190 - 4611874_988_1186 at #191 4611874_988_1186 at #191 - 4611874_988_1186 at #195: S18 4611874_988_1186 at #195: S18 S 4611874_988_1186 at #196: K19 4611874_988_1186 at #196: K19 K 4611874_988_1186 at #197: L20 4611874_988_1186 at #197: L20 L 4611874_988_1186 at #198: W21 4611874_988_1186 at #198: W21 W 4611874_988_1186 at #235: K22 4611874_988_1186 at #235: K22 K 4611874_988_1186 at #236: V23 4611874_988_1186 at #236: V23 V 4611874_988_1186 at #237: E24 4611874_988_1186 at #237: E24 E 4611874_988_1186 at #238: D25 4611874_988_1186 at #238: D25 D 4611874_988_1186 at #240: G26 4611874_988_1186 at #240: G26 G 4611874_988_1186 at #268: V27 4611874_988_1186 at #268: V27 V 4611874_988_1186 at #269: I28 4611874_988_1186 at #269: I28 I 4611874_988_1186 at #270: Y29 4611874_988_1186 at #270: Y29 Y 4611874_988_1186 at #294: G34 4611874_988_1186 at #294: G34 G 4611874_988_1186 at #295: N35 4611874_988_1186 at #295: N35 N 4611874_988_1186 at #296: K36 4611874_988_1186 at #296: K36 K 4611874_988_1186 at #297: L37 4611874_988_1186 at #297: L37 L 4611874_988_1186 at #298: K38 4611874_988_1186 at #298: K38 K 4611874_988_1186 at #299: A39 4611874_988_1186 at #299: A39 A 4611874_988_1186 at #300: N40 4611874_988_1186 at #300: N40 N 4611874_988_1186 at #301: S41 4611874_988_1186 at #301: S41 S 4611874_988_1186 at #303: F42 4611874_988_1186 at #303: F42 F 4611874_988_1186 at #304: L43 4611874_988_1186 at #304: L43 L 4611874_988_1186 at #305: V44 4611874_988_1186 at #305: V44 V 4611874_988_1186 at #306: W45 4611874_988_1186 at #306: W45 W 4611874_988_1186 at #312: E46 4611874_988_1186 at #312: E46 E 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#689: K190 4611874_988_1186 at #689: K190 K 4611874_988_1186 at #690: A191 4611874_988_1186 at #690: A191 A 4611874_988_1186 at #691: W192 4611874_988_1186 at #691: W192 W 4611874_988_1186 at #694: F193 4611874_988_1186 at #694: F193 F 4611874_988_1186 at #695: K194 4611874_988_1186 at #695: K194 K 4611874_988_1186 at #696: N195 4611874_988_1186 at #696: N195 N 4611874_988_1186 at #697: I196 4611874_988_1186 at #697: I196 I 4611874_988_1186 at #698: Q197 4611874_988_1186 at #698: Q197 Q 4611874_988_1186 at #699: L198 4611874_988_1186 at #699: L198 L 4611874_988_1186 at #700: K199 4611874_988_1186 at #700: K199 K download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory