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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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Highlight proteins:

0.880 0.809 0.707 11227501_33_203: single domain, from Cyclobacterium marinum DSM 745 2761067_1173_1341: with redox domain, from Blastopirellula marina DSM 3645 0.866 4911453_35_208: single domain, from Gemmata obscuriglobus UQM 2246 11272043_27_202: single domain, from Isosphaera pallida IS1B, ATCC 43644 0.811 0.719 0.489 6378172_468_664: with other domain, from Bacteroides cellulosilyticus DSM 14838 0.861 6003860_25_205: with redox domain, from Verrucomicrobium spinosum DSM 4136 7396463_28_209: single domain, from Dyadobacter fermentans DSM 18053 0.910 2761156_23_206: single domain, from Blastopirellula marina DSM 3645 560752_63_281: single domain, from Pirellula sp. 1 0.551 11268538_332_511: with other domain, from Isosphaera pallida IS1B, ATCC 43644 0.513 6250794_21_205: with redox domain, from Chthoniobacter flavus Ellin428 10267460_32_215: single domain, from Spirosoma linguale DSM 74 1 /site single domain, from Cyclobacterium marinum DSM 745 11227501_33_203 single domain, from Cyclobacterium marinum DSM 745 with redox domain, from Blastopirellula marina DSM 3645 2761067_1173_1341 with redox domain, from Blastopirellula marina DSM 3645 single domain, from Gemmata obscuriglobus UQM 2246 4911453_35_208 single domain, from Gemmata obscuriglobus UQM 2246 single domain, from Isosphaera pallida IS1B, ATCC 43644 11272043_27_202 single domain, from Isosphaera pallida IS1B, ATCC 43644 with other domain, from Bacteroides cellulosilyticus DSM 14838 6378172_468_664 with other domain, from Bacteroides cellulosilyticus DSM 14838 with redox domain, from Verrucomicrobium spinosum DSM 4136 6003860_25_205 with redox domain, from Verrucomicrobium spinosum DSM 4136 single domain, from Dyadobacter fermentans DSM 18053 7396463_28_209 single domain, from Dyadobacter fermentans DSM 18053 single domain, from Blastopirellula marina DSM 3645 2761156_23_206 single domain, from Blastopirellula marina DSM 3645 single domain, from Pirellula sp. 1 560752_63_281 single domain, from Pirellula sp. 1 with other domain, from Isosphaera pallida IS1B, ATCC 43644 11268538_332_511 with other domain, from Isosphaera pallida IS1B, ATCC 43644 with redox domain, from Chthoniobacter flavus Ellin428 6250794_21_205 with redox domain, from Chthoniobacter flavus Ellin428 single domain, from Spirosoma linguale DSM 74 10267460_32_215 single domain, from Spirosoma linguale DSM 74 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory