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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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Highlight proteins:

0.213 0.802 557004_164_355: single domain, near sugar dehydrogenase, from Pirellula sp. 1 4612146_159_339: single domain, from Lentisphaera araneosa HTCC2155 0.880 0.840 10307987_154_329: single domain, from Pirellula staleyi DSM 6068 4616236_34_216: single domain, from Lentisphaera araneosa HTCC2155 557181_269_442: single domain, from Pirellula sp. 1 0.5 /site single domain, near sugar dehydrogenase, from Pirellula sp. 1 557004_164_355 single domain, near sugar dehydrogenase, from Pirellula sp. 1 single domain, from Lentisphaera araneosa HTCC2155 4612146_159_339 single domain, from Lentisphaera araneosa HTCC2155 single domain, from Pirellula staleyi DSM 6068 10307987_154_329 single domain, from Pirellula staleyi DSM 6068 single domain, from Lentisphaera araneosa HTCC2155 4616236_34_216 single domain, from Lentisphaera araneosa HTCC2155 single domain, from Pirellula sp. 1 557181_269_442 single domain, from Pirellula sp. 1 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory