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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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Highlight proteins:

0.489 6378172_468_664: with other domain, from Bacteroides cellulosilyticus DSM 14838 0.861 6003860_25_205: with redox domain, from Verrucomicrobium spinosum DSM 4136 7396463_28_209: single domain, from Dyadobacter fermentans DSM 18053 0.5 /site with other domain, from Bacteroides cellulosilyticus DSM 14838 6378172_468_664 with other domain, from Bacteroides cellulosilyticus DSM 14838 with redox domain, from Verrucomicrobium spinosum DSM 4136 6003860_25_205 with redox domain, from Verrucomicrobium spinosum DSM 4136 single domain, from Dyadobacter fermentans DSM 18053 7396463_28_209 single domain, from Dyadobacter fermentans DSM 18053 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory