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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.808 10356341_141_326: single domain, from Coraliomargarita akajimensis DSM 45221 0.953 0.882 0.468 0.460 0.115 0.876 7398304_63_256: single domain, from Dyadobacter fermentans DSM 18053 0.886 3723559_59_253: single domain, near sugar dehydrogenase, from Parabacteroides distasonis ATCC 8503 0.992 5848954_85_286: single domain, from Caulobacter crescentus NA1000 0.052 Pedo557__CA265_RS22975: single domain 3-ketotrehalose hydrolase from Pedobacter sp. GW460-11-11-14-LB5 11045354_54_254: single domain, from Hymenobacter roseosalivarius AA-718, DSM 11622 11293044_51_238: single domain, from Planctomyces brasiliensis DSM 5305 4612339_494_704: with other domain, from Lentisphaera araneosa HTCC2155 0.338 6000757_65_257: single domain, from Verrucomicrobium spinosum DSM 4136 6004177_75_267: single domain, from Verrucomicrobium spinosum DSM 4136 0.777 0.633 10356898_71_256: single domain, from Coraliomargarita akajimensis DSM 45221 4614844_78_263: single domain, from Lentisphaera araneosa HTCC2155 2220738_87_285: single domain, from Solibacter usitatus Ellin6076 Korea__Ga0059261_0549: single domain, from Sphingomonas koreensis DSMZ 15582 1 /site single domain, from Coraliomargarita akajimensis DSM 45221 10356341_141_326 single domain, from Coraliomargarita akajimensis DSM 45221 single domain, from Dyadobacter fermentans DSM 18053 7398304_63_256 single domain, from Dyadobacter fermentans DSM 18053 single domain, near sugar dehydrogenase, from Parabacteroides distasonis ATCC 8503 3723559_59_253 single domain, near sugar dehydrogenase, from Parabacteroides distasonis ATCC 8503 single domain, from Caulobacter crescentus NA1000 5848954_85_286 single domain, from Caulobacter crescentus NA1000 single domain 3-ketotrehalose hydrolase from Pedobacter sp. GW460-11-11-14-LB5 Pedo557__CA265_RS22975 single domain 3-ketotrehalose hydrolase from Pedobacter sp. GW460-11-11-14-LB5 single domain, from Hymenobacter roseosalivarius AA-718, DSM 11622 11045354_54_254 single domain, from Hymenobacter roseosalivarius AA-718, DSM 11622 single domain, from Planctomyces brasiliensis DSM 5305 11293044_51_238 single domain, from Planctomyces brasiliensis DSM 5305 with other domain, from Lentisphaera araneosa HTCC2155 4612339_494_704 with other domain, from Lentisphaera araneosa HTCC2155 single domain, from Verrucomicrobium spinosum DSM 4136 6000757_65_257 single domain, from Verrucomicrobium spinosum DSM 4136 single domain, from Verrucomicrobium spinosum DSM 4136 6004177_75_267 single domain, from Verrucomicrobium spinosum DSM 4136 single domain, from Coraliomargarita akajimensis DSM 45221 10356898_71_256 single domain, from Coraliomargarita akajimensis DSM 45221 single domain, from Lentisphaera araneosa HTCC2155 4614844_78_263 single domain, from Lentisphaera araneosa HTCC2155 single domain, from Solibacter usitatus Ellin6076 2220738_87_285 single domain, from Solibacter usitatus Ellin6076 single domain, from Sphingomonas koreensis DSMZ 15582 Korea__Ga0059261_0549 single domain, from Sphingomonas koreensis DSMZ 15582 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory