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Comment: DUF1080 is a family of hydrolases and includes putative 3-ketoglycoside hydrolases. The putative active site was identified from the structure of BT2157 (PDB:3osd). In the tree, BT2157 and other 3-ketoglycoside hydrolases are colored green, and endoglucanase THTE_1561 is in red. These members of DUF1080 were taken from MicrobesOnline (using hits to PFam PF06439.11 with 80 bits or higher), clustered at 60% identity to reduce the number of sequences, and aligned using hmmalign.

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0.917 11261816_60_268: single domain, from Flexibacter tractuosus DSM 4126 0.355 0.972 3723687_51_268: single domain, from Parabacteroides distasonis ATCC 8503 BT2157: single domain 3-ketoglycoside hydrolase from Bacteroides thetaiotaomicron VPI-5482 3722639_36_242: single domain, from Parabacteroides distasonis ATCC 8503 0.5 /site single domain, from Flexibacter tractuosus DSM 4126 11261816_60_268 single domain, from Flexibacter tractuosus DSM 4126 single domain, from Parabacteroides distasonis ATCC 8503 3723687_51_268 single domain, from Parabacteroides distasonis ATCC 8503 single domain 3-ketoglycoside hydrolase from Bacteroides thetaiotaomicron VPI-5482 BT2157 single domain 3-ketoglycoside hydrolase from Bacteroides thetaiotaomicron VPI-5482 single domain, from Parabacteroides distasonis ATCC 8503 3722639_36_242 single domain, from Parabacteroides distasonis ATCC 8503 download SVG

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory