Searching for up to 100 curated homologs for 14149 FitnessBrowser__Keio:14149 (428 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

Removed hits that are identical to the query, leaving 19

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

thrC / CAA43214.1 threonine synthase from Serratia marcescens (see paper)
    84% identity, 99% coverage of query (743 bits)

4f4fA / Q8YFS0 X-ray crystal structure of plp bound threonine synthase from brucella melitensis
    34% identity, 96% coverage of query (246 bits)

Q8YFS0 threonine synthase (EC 4.2.3.1) from Brucella melitensis (see paper)
    34% identity, 96% coverage of query (246 bits)

N515DRAFT_0575 threonine synthase (EC 4.2.3.1) from Dyella japonica UNC79MFTsu3.2
    37% identity, 96% coverage of query (244 bits)

AgTHR4 / CAA62506.1 AgTHR4 from Eremothecium gossypii (see paper)
    34% identity, 92% coverage of query (216 bits)

THRC_YEAST / P16120 Threonine synthase; TS; EC 4.2.3.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P16120 threonine synthase (EC 4.2.3.1) from Saccharomyces cerevisiae (see paper)
    32% identity, 96% coverage of query (213 bits)

1kl7A / P16120 Crystal structure of threonine synthase from yeast (see paper)
    33% identity, 95% coverage of query (209 bits)

thrC / AAF21130.1 threonine synthase from Methylobacillus flagellatus (see paper)
    30% identity, 100% coverage of query (201 bits)

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Build an alignment for 14149 and 8 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

THRC_CORGL / P23669 Threonine synthase; TS; EC 4.2.3.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
    29% identity, 96% coverage of query (196 bits)

thrC / CAA82670.1 THREONINE SYNTHASE from Corynebacterium glutamicum (see paper)
    29% identity, 96% coverage of query (196 bits)

Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    31% identity, 89% coverage of query (196 bits)

PerR / VIMSS78912 PerR regulator of Iron homeostasis; Manganese homeostasis; Oxidative stress response, effector Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide (repressor) from Lactococcus lactis subsp. lactis Il1403
    32% identity, 89% coverage of query (193 bits)

8g1yA / A0A0H2US33 Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
    32% identity, 90% coverage of query (184 bits)

Q2SWH9 threonine synthase (EC 4.2.3.1) from Burkholderia thailandensis (see paper)
    30% identity, 90% coverage of query (183 bits)

THNS2_HUMAN / Q86YJ6 Threonine synthase-like 2; TSH2; Secreted osteoclastogenic factor of activated T-cells; SOFAT; EC 4.2.3.- from Homo sapiens (Human) (see paper)
    31% identity, 91% coverage of query (163 bits)

THNS2_MOUSE / Q80W22 Threonine synthase-like 2; TSH2; mTSH2; EC 4.2.3.- from Mus musculus (Mouse) (see paper)
    30% identity, 91% coverage of query (160 bits)

THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    25% identity, 76% coverage of query (74.3 bits)

2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine
    26% identity, 76% coverage of query (74.3 bits)

2c2gA / Q9S7B5 Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
    24% identity, 76% coverage of query (68.9 bits)

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