Searching for up to 100 curated homologs for 14408 FitnessBrowser__Keio:14408 (460 a.a.)
Found high-coverage hits (≥70%) to 29 curated proteins.
Removed hits that are identical to the query, leaving 28
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YicJ / b3657 putative xyloside transporter YicJ from Escherichia coli K-12 substr. MG1655 (see 5 papers)
TC 2.A.2.3.4 / P31435 Probable α-xyloside uptake permease, YicJ from Escherichia coli (see 4 papers)
44% identity, 97% coverage of query (357 bits)
Sama_1401 D-cellobiose transporter (MFS superfamily) from Shewanella amazonensis SB2B
38% identity, 96% coverage of query (297 bits)
TC 2.A.2.3.2 / P94488 Pentoside permease from Bacillus subtilis (see 2 papers)
33% identity, 98% coverage of query (236 bits)
XYLP_LACPE / P96792 Isoprimeverose transporter; Isoprimeverose cation symporter from Lactiplantibacillus pentosus (Lactobacillus pentosus) (see 2 papers)
TC 2.A.2.3.3 / P96792 Isoprimeverose (α-D xylopyranosyl-(1,6)-D-glucopyranose) permease [xylose is not a substrate] from Lactobacillus pentosus (see paper)
xylP xylose transporter from Lactobacillus pentosus (see paper)
33% identity, 97% coverage of query (216 bits)
UIDB2_ECOLI / P0CE45 Glucuronide carrier protein; Glucuronide permease from Escherichia coli (strain K12) (see paper)
TC 2.A.2.3.1 / P0CE45 Glucuronide permease, UidB, GusB, UidP from Escherichia coli (strain K12) (see 2 papers)
31% identity, 98% coverage of query (177 bits)
UidP / b1616 glucuronide:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
uidB / P0CE44 glucuronide:H+ symporter from Escherichia coli (strain K12) (see 3 papers)
31% identity, 98% coverage of query (173 bits)
Build an alignment for 14408 and 6 homologs with ≥ 30% identity
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YihP / b3877 putative 2,3-dihydroxypropane-1-sulfonate export protein from Escherichia coli K-12 substr. MG1655 (see 3 papers)
YIHP_ECOLI / P32137 Putative 2,3-dihydroxypropane-1-sulfonate exporter from Escherichia coli (strain K12) (see paper)
28% identity, 90% coverage of query (173 bits)
MelB / b4120 melibiose:H+/Na+/Li+ symporter from Escherichia coli K-12 substr. MG1655 (see 25 papers)
melB / P02921 melibiose:H+/Na+/Li+ symporter from Escherichia coli (strain K12) (see 28 papers)
MELB_ECOLI / P02921 Melibiose permease; Melibiose carrier; Melibiose transporter; Melibiose/cation symporter; Na+ (Li+)/melibiose symporter; Thiomethylgalactoside permease II from Escherichia coli (strain K12) (see 10 papers)
28% identity, 98% coverage of query (171 bits)
TC 2.A.2.1.1 / A7ZUZ0 Melibiose permease. Catalyzes the coupled stoichiometric symport of a galactoside with a cation (either Na+, Li+, or H+). Based on LacY, a 3-d model has been derived (Yousef and Guan, 2009). Asp55 and Asp59 are essential for Na+ from Escherichia coli O139:H28 (strain E24377A / ETEC) (see paper)
28% identity, 98% coverage of query (170 bits)
MELB_SALTY / P30878 Melibiose permease; Melibiose carrier; Melibiose transporter; Melibiose/cation symporter; Na+ (Li+)/melibiose symporter; Thiomethylgalactoside permease II from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 5 papers)
27% identity, 96% coverage of query (167 bits)
MELB_KLEAE / O07366 Melibiose permease; Melibiose carrier; Melibiose transporter from Klebsiella aerogenes (Enterobacter aerogenes) (see paper)
29% identity, 98% coverage of query (164 bits)
7l16A / P30878 Crystal structure of sugar-bound melibiose permease melb (see paper)
27% identity, 96% coverage of query (164 bits)
7l17A Crystal structure of sugar-bound melibiose permease melb
27% identity, 96% coverage of query (164 bits)
MELB_KLEPN / Q02581 Melibiose permease; Melibiose carrier; Melibiose transporter from Klebsiella pneumoniae (see paper)
melB / AAA25067.1 melibiose carrier from Klebsiella pneumoniae (see paper)
29% identity, 98% coverage of query (163 bits)
SquO / b3876 putative sulfoquinovose transporter from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yihO / P32136 putative sulfoquinovose transporter from Escherichia coli (strain K12) (see 3 papers)
YIHO_ECOLI / P32136 Putative sulfoquinovose importer from Escherichia coli (strain K12) (see paper)
26% identity, 97% coverage of query (145 bits)
lacP / CAA74936.1 lactose permease from Staphylococcus xylosus (see paper)
28% identity, 90% coverage of query (133 bits)
NLS1A_DANRE / Q5U3U7 Sodium-dependent lysophosphatidylcholine symporter 1-A; NLS1-A; Sodium-dependent LPC symporter 1-A; Major facilitator superfamily domain-containing protein 2A-A from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
25% identity, 95% coverage of query (108 bits)
LACY_LACHE / Q7WTB2 Lactose permease; Lactose transport protein; Lactose transporter; Lactose-proton symporter; EC 2.7.1.- from Lactobacillus helveticus (Lactobacillus suntoryeus) (see paper)
24% identity, 88% coverage of query (100 bits)
TC 2.A.2.1.2 / B3W8U5 Probable fucosyl-α-1,6-N-acetylglucosamine uptake porter, AlfD (next to and in an operon with a fucosidase (AlfA) specific for this disaccharide which is present in mammalian glycoproteins, glycolipids and milk from Lactobacillus casei (strain BL23)
25% identity, 95% coverage of query (86.7 bits)
MFS2B_HUMAN / A6NFX1 Sphingosine-1-phosphate transporter MFSD2B; Major facilitator superfamily domain-containing protein 2B; hMfsd2b from Homo sapiens (Human) (see 2 papers)
25% identity, 97% coverage of query (83.6 bits)
NLS1B_DANRE / Q6DEJ6 Sodium-dependent lysophosphatidylcholine symporter 1-B; NLS1-B; Sodium-dependent LPC symporter 1-B; Major facilitator superfamily domain-containing protein 2A-B from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
23% identity, 98% coverage of query (82.8 bits)
NLS1_MOUSE / Q9DA75 Sodium-dependent lysophosphatidylcholine symporter 1; NLS1; Sodium-dependent LPC symporter 1; Major facilitator superfamily domain-containing protein 2A; Mfsd2a from Mus musculus (Mouse) (see 6 papers)
22% identity, 99% coverage of query (82.0 bits)
8d2sA / Q6DEJ6 Zebrafish mfsd2a isoform b in inward open ligand bound conformation (see paper)
23% identity, 96% coverage of query (80.5 bits)
galP / CAB44214.1 galactose permease from Lactococcus lactis (see paper)
25% identity, 96% coverage of query (76.6 bits)
NLS1_CHICK / F1NCD6 Sodium-dependent lysophosphatidylcholine symporter 1; NLS1; Sodium-dependent LPC symporter 1; Major facilitator superfamily domain-containing protein 2A; GgMFSD2A from Gallus gallus (Chicken) (see paper)
22% identity, 96% coverage of query (75.1 bits)
TC 2.A.2.5.1 / Q93KC2 Saturated and unsaturated oligogalacturonide transporter, TogT (transports di- to tetrasaccharide pectin degradation products which consist of D-galacuronate, sometimes with 4-deoxy-L-threo-5- hexosulose uronate at the reducing position) from Erwinia chrysanthemi (see paper)
23% identity, 99% coverage of query (71.6 bits)
TC 2.A.2.2.1 / P23936 Lactose permease, LacS. Mediates uptake of β-galactooligosaccharides, lactitol, and a broad range of prebiotic β-galactosides that selectively stimulate beneficial gut microbiota from Streptococcus thermophilus (see 2 papers)
23% identity, 85% coverage of query (70.1 bits)
NLS1_HUMAN / Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1; NLS1; Sodium-dependent LPC symporter 1; Major facilitator superfamily domain-containing protein 2A; HsMFSD2A; MFSD2a from Homo sapiens (Human) (see 9 papers)
TC 2.A.2.3.8 / Q8NA29 Major Facilitator Superfamily Domain containing 2A, MFSD2A (543aas, 12 TMSs). Plays a role in thermogenesis via β-adrenergic signaling from Homo sapiens (see 8 papers)
21% identity, 99% coverage of query (70.1 bits)
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Lawrence Berkeley National Laboratory